Zycolchin 0.5 mg (Colchicine)

Zycolchin is well established in the treatment of acute flares of gouty arthritis (a condition caused by too much uric acid in the blood). The problem develops when an excess amount of uric acid causes inflammation in joints. The medication dose does not cure gout, but it will prevent acute flares of gout. It is not an ordinary pain reliever and will not relieve most kinds of pain. It may also be prescribed to treat a rare condition called familial Mediterranean fever in adults and children older than four years of age. Its active component Colchicine, an anti-inflammatory agent, is a tricyclic alkaloid prepared from the dried corms and seeds of Colchicum autumnale.

Zycolchin general information

What is Zycolchin used for?

Zycolchin is used for the prevention and treatment of acute attacks of gouty arthritis. It is also useful in treating familial Mediterranean fever. The anti-inflammatory agent improves the patient condition by blocking the movement of white blood cells. Your physician may also prescribe this medicine for purposes not mentioned in this document.

How does Zycolchin work?

Zycolchin comprises of an active ingredient Zycolchin, which works by interfering with the functions of the white blood cells and perpetuating the inflammatory response to monosodium urate crystals. In this way, it decreases pain and inflammation in acute attacks of gout.

Where to buy Zycolchin online?

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What does Zycolchin contain?

Zycolchin 0.5 mg contains the active ingredient colchicine, which is an alkaloid. Each tablet delivers 0.5 mg of the beneficial ingredient to the patient. 

What are the side effects of Zycolchin?

• Gastrointestinal problems: abdominal pain, nausea, diarrhea, vomiting
• Hematological issues: aplastic anemia, thrombocytopenia, agranulocytosis, thrombocytopenia, and leukopenia
• Dermatological problems: alopecia
• Neurological problems: peripheral neuritis

What medications interact with Zycolchin?

• Concurrent use of clarithromycin, indinavir, ritonavir, nefazodone, telithromycin, ketoconazole, tipranavir, darunavir, itraconazole, saquinavir, nelfinavir, atazanavir, or lopinavir may increase the risk of toxicity. 
• Coadministration of glycoprotein inhibitors such as ranolazine and cyclosporine may increase levels and toxicity.
• Moderate CYP3A4 inhibitors including erythromycin, verapamil, aprepitant, fluconazole, or fosamprenavir may also increase the risk of toxicity.
• Rhabdomyolysis may develop with fenofibrate, digoxin, or gemfibrozil.
• The additive bone marrow may develop with the concurrent use of bone marrow depressants or radiotherapy.
• Gastrointestinal problems may occur with concomitant use of NSAIDs.
• Avoid using vitamin B tablet with Zycolchicin as this may cause reversible malabsorption of vitamin B12.

When should Zycolchin not be used?

Zycolchin is not suitable for patients with known hypersensitivity to colchicines and other inactive ingredients of the formulation.

The medicine should be used carefully in the following conditions:

• Elderly patients
• Renal impairment
• Pediatric patients
• Lactating mothers

How should Zycolchin be used?

• The usual initial dose for the treatment of gout is two Zycolchin tablets, followed by one tablet every two to three hours until the complete results are achieved.
• You should immediately stop the treatment and inform your physician if you experience diarrhea
• You are not supposed to exceed 12 Zycolchin tablets a day as a course of treatment.
• It is recommended that a patient should wait for three days before initiating another course of therapy.
• For the prevention of the acute attacks of gout, it is recommended to take two to three tablets daily. Your physician will decide the best dose for you.

How long should you use Zycolchin?

Take Zycochin 0.5 mg as long as it is recommended to you. Try not to stop in between during the treatment as it may take several weeks or longer to see the effects of this anti-inflammatory agent. If your condition still does not improve after the prescribed period, visit your physician.

Missed dose of Zycolchin

If you miss a dose of Zycolchin, take a missed dose as soon as you think about it. If the time to take the next dose is close, skip the missed dose and go back to your normal dosing schedule. Do not compensate the missed one by taking an extra tablet.

How should Zycolchin be stored?

• Store it at controlled room temperature
• Keep the tablets away from the reach and sight of the children
• Store the medicine in its original package to protect from light
• Place it away from heat and moisture