Seroflo Ciphaler 50/250 mcg

SKU 2433
Generic For Advair
Strength 50/250 mcg
Generic Name Salmeterol Fluticasone Propionate
Manufacturer Cipla

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Seroflo Ciphaler 50/250 MCG

Seroflo Ciphaler 50/250 mcg is an inhaled powdered drug containing both salmeterol 50 and Fluticasone propionate 250 mcg. These two drugs delivered via ciphaler. It is effective as a maintenance treatment in patients 4 years of age and older.  The combination of medicine equally works patients with airflow obstruction; it reduces exacerbations in patients with chronic obstructive pulmonary disease or COPD.

Seroflo contains two medicines:

  • Salmeterol belongs to a class of drugs known as long-acting beta-agonists which cause the muscles in your lungs to stay relaxed, preventing symptoms such as wheezing and shortness of breath.  These symptoms developed when muscles around the airways contracted, making it hard for you to breathe. Sometimes wheezing can be life-threatening as it can stop breathing and cause death if left untreated. The medicine is beneficial for those who have asthma and chronic obstructive disease.
  • Fluticasone propionate - It is an inhaled corticosteroid drug that reduces irritation and swelling of the lungs' airways. Inflammation in the lungs can contribute to asthma symptoms.

By inhaling the combination drug, the doses directly reach the target site, i.e., airways in the lungs—also, this way the amount of inhaled drug doses can be used as small as possible. Therefore, unwanted effects can be reduced, and drug response can be easily detected.

Usage Information

For maintenance treatment of asthma in patients aged 12 years and above- one inhalation twice daily. The initial dose of the drug depends on asthma severity. For maintenance treatment of asthma in patients 4 to 11 years and COPD- one inhalation twice daily. Use the drug as advised by your doctor. Sudden discontinuation of this asthma medicine may cause trouble for you; your symptoms may come back and lead to severe complications. Seroflo should not treat acute asthma episodes or COPD that needs intensive measures. Patients with severe hypersensitivity to milk proteins should not use it without the doctor’s permission.


The medicine does not relieve sudden symptoms. To treat sudden asthma episodes, it is important always to carry short-acting beta-agonist medicine to treat a sudden onset of wheezing and shortness of breath. If you do not have a short-acting bronchodilator, speak to your doctor to have one prescribed for you. Do not stop using it unless instructed by your doctor because your breathing pattern might worsen. It should only be used under the supervision of a doctor. Your doctor will prescribe this combination medicine a single strength asthma controller medicine that does not control your asthma symptoms or needs a combination dose to suppress your condition. Call your doctor straight away if your symptoms worsen while using Seroflo ciphaler. You may need a different asthma treatment.  Long-acting beta-agonists may increase the risk of asthma-related deaths, hence only prescribe to the recommended patient population. Do not use to treat acute symptoms.

Side Effects of Seroflo Ciphaler 50/250 mcg

Most common side effects of Seroflo 50/250 mcg in asthma patients are upper respiratory tract inflammation, bronchitis, nausea, vomiting, cough, headache, oral candidiasis, and pharyngitis. People suffering from COPD may experience throat irritation, viral respiratory infections. Musculoskeletal pain, oral candidiasis, headaches, dysphonia, and pneumonia. There is an increased risk of pneumonia in patients with COPD. Patients should monitor the signs and symptoms of asthma.  Do not use this combination medicine with additional long-acting beta-agonist as it may increase the risk of overdose. The medicine may also affect the growth of paediatric patients.

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