Accuzide Forte 20/12.5 mg
Available Dosages
| Description | |
|---|---|
| SKU | 857 |
| Generic For | Accuzide Forte |
| Strength | 20/12.5 mg |
| Manufacturer | Pfizer (Turkey) |
| Active Ingredient | Quinapril Hydroclroride - Hrdrochlorothiazide |
Out Of Stock
Accuzide Forte 20/12.5 mg – Affordable Accuzide Forte Alternative
Accuzide Fortre 20/12.5mg is a fixed-combination tablet and active ingredients are Quinapril and Hydrochlorothiazide that combines an angiotensin-converting enzyme (ACE) inhibitor, quinapril, and a thiazide diuretic, hydrochlorothiazide. Quinapril lowers the blood pressure and hydrochlorothiazide diuretic stops the body from absorbing too much salt, which can lead to fluid retention. Accuzide Forte is used to treat hypertension.Quinapril is a white to off-white amorphous powder that is readily soluble in aqueous solvents.
Hydrochlorothiazide is a white to off-white, crystalline powder which is slightly soluble in water but readily soluble in sodium hydroxide solution.It is available for oral use as fixed combinational drug (quinapril with hydrochlorothiazide) in the strength of 20/12.5mg.
What is Accuzide used for?
Accuzide Forte contains a combination of quinapril, which makes the group of medicines called ACE inhibitor (ACE inhibitor and hydrochlorothiazide, which belongs to the group of medicines called diuretics. Quinapril dilates blood vessels resulting in the lowering of blood pressure and Hydrochloride helps remove excess fluid from the body. The tablets are used to treat hypertension.
How does Accuzide Forte works?
Accuzide Forte contains the active ingredients Quinapril and Hydrochlorothiazide.
Quinapril:
It belongs to the class of ACE inhibitor. It relaxes the constructed blood vessels and helps heart in pumping the blood more easily. It reduces the post heart attack damage by supplying sufficient oxyegen, nutrient supply. In case of kidney problem, it improves the blood supply in the vessels found in the kidneys and reduces the chances of getting diabetes post effects and hypertension.
Hydrochlorothiazide:
It belongs to the class of diuretics. It remove excess of fluid from the body by increasing the urine production also removes salt, water, and decreases the fluid circulation in blood vessels. This way, pressure in the blood vessels gets decreased and hypertensive effect is achieved.
What are the side effects of Accuzide Forte ?
Like all medicines, Accuzide Forte can cause side effects, although not everybody gets them.
The common side effects are listed below:
- Headache
- Blurred vision
- Dizziness
- Tiredness
- Numbness
- Weakness
- Nervousness
Some serious and rare effects associated with this combination are as follows:
- Impotency
- Change in taste receptor
- Tachycardia
- Depression
- Pancreatitis
- Confusion
When should Accuized Forte not be used?
You should not take Accuizide Forte 20/12.5 mg if you:
- Have heart disease
- Have kidney disease
- Have gout
- Have diabetes and asthma
- Are pregnant or planning to be
- Have allergy to quinapril and hydrochoothiazide
How long Accuzide Forte should be used?
Always take the medicine prescribed by the physician. It is very important to take your medicine as prescribed by the physician. Various factors are observed before a disease. Doctor will prescribe best suitable dose for you treatment.
Missed dose of Accuzide Forte
Take the next medicine as soon as you remember, if time of the nest dose, just take this one: don’t take more tablets to recover the previous missed dose.
How should Accuzide Forte be stored?
- Keep out of the reach and sight of children.
- Store at temperature in the original packaging. Do not freeze the tablets.
What is Accuzide Forte 20/12.5mg used for?
Accuzide Forte contains quinapril 20mg and hydrochlorothiazide (HCTZ) 12.5mg, combining an ACE inhibitor with a thiazide diuretic in a single tablet for hypertension management. Quinapril relaxes blood vessels by blocking angiotensin II formation, while HCTZ promotes Sodiumium and fluid excretion via the kidneys. Together they address blood pressure from two complementary mechanisms, providing greater control than either drug alone in patients with moderate to severe hypertension.
How do quinapril and HCTZ work together to lower blood pressure?
Quinapril blocks ACE to prevent angiotensin II-mediated vasoconstriction and aldosterone-driven fluid retention. Hydrochlorothiazide enhances renal Sodiumium and water excretion, reducing blood volume. HCTZ also activates the renin-angiotensin system — a reactive increase that quinapril simultaneously blocks, making the combination synergistic. This dual mechanism achieves greater blood pressure reduction than either drug at higher single-agent doses, while potentially reducing dose-related side effects.
How should Accuzide Forte 20/12.5mg be taken?
Accuzide Forte is taken once daily, preferably in the morning to align HCTZ's diuretic action with daytime activity (minimising overnight urination). Take with or without food. Consistency of timing is important for stable blood pressure control. Patients should stay well-hydrated, especially in hot weather or during exercise, to minimise the risk of dehydration and electrolyte disturbance from the HCTZ component.
How quickly does Accuzide Forte lower blood pressure?
The combination begins lowering blood pressure within 1–2 hours of the first dose, with measurable reductions evident in the first few days. Consistent control typically develops within 2–4 weeks of once-daily use. Regular blood pressure monitoring at home during the first month helps assess whether the 20/12.5 mg combination is achieving targets or whether dose adjustment is needed.
Is Accuzide Forte safe for long-term use?
Accuzide Forte is approved for long-term hypertension management. Routine monitoring of blood pressure, potassium, Sodiumium, creatinine, and uric acid is recommended, as HCTZ can lower potassium and Sodiumium while raising uric acid. The quinapril component may modestly raise potassium — balancing the HCTZ effect. Regular clinical reviews every 6–12 months ensure electrolyte and renal balance are maintained safely.
Can Accuzide Forte interact with other blood pressure medications?
Adding other antihypertensives to Accuzide Forte increases the risk of excessive blood pressure reduction. NSAIDs reduce the effectiveness of both quinapril and HCTZ. The HCTZ component can interact with lithium (raising lithium toxicity risk) and antidiabetic drugs (HCTZ can raise blood glucose). Potassium supplements or potassium-sparing diuretics must be used cautiously with quinapril to avoid hyperkalaemia.
How does Accuzide Forte compare to Zestoretic (lisinopril/HCTZ)?
Accuzide Forte (quinapril/HCTZ 20/12.5mg) and Zestoretic (lisinopril/HCTZ 10/12.5mg or 20/12.5mg) are both ACE inhibitor-thiazide combinations. Lisinopril is directly active and not affected by hepatic metabolism; quinapril requires liver conversion to quinaprilat but has higher tissue ACE affinity. Both are clinically effective combination antihypertensives; the choice typically depends on prescriber preference, patient tolerance, and cost.
Is Accuzide Forte equivalent to branded Accuretic?
Yes. Accuzide Forte contains the same active ingredients — quinapril 20mg and HCTZ 12.5mg — as Accuretic (branded in the US). Both are manufactured to the same bioequivalence standards and deliver identical blood pressure-lowering effects. Generic Accuzide Forte provides the same dual-mechanism antihypertensive control at a significantly lower cost.
Can I order quinapril/HCTZ online from PremiumRxDrugs?
Yes. PremiumRxDrugs.com ships Accuzide Forte and other combination antihypertensives internationally to the USA, UK, Australia, and many other countries. The prescription upload system, genuine medicines at competitive prices, and free worldwide shipping on qualifying orders make them a trusted pharmacy for patients on long-term combination blood pressure therapy.
What side effects does Accuzide Forte 20/12.5mg cause?
Side effects from Accuzide Forte include dry cough (from quinapril), dizziness, electrolyte disturbances (low potassium and Sodiumium from HCTZ), increased urination, elevated uric acid, mild creatinine rises, and headache. Angioedema from quinapril is rare but serious. Photosensitivity skin reactions can occur with HCTZ — use sunscreen when outdoors. Report any facial or throat swelling immediately.
Who should not take Accuzide Forte?
Accuzide Forte is contraindicated in pregnancy, history of ACE inhibitor angioedema, anuria, severe renal or hepatic impairment, and concurrent aliskiren use in diabetics. Sulphonamide hypersensitivity is a contraindication for the HCTZ component. Patients with gout or hyperuricaemia should be monitored closely, as HCTZ can raise uric acid levels. Breastfeeding women should not use this combination.
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