|Generic Name||Amlodipine Besilate|
|Pack Size||Qty||Price Per Pill or Unit||Price||Cart|
|30 Tablet/s||US$ 0.13||US$ 3.78|
|60 Tablet/s||US$ 0.13||US$ 7.56|
|90 Tablet/s||US$ 0.13||US$ 11.34|
Amlopres 5mg is a drug that contains Amlodipine Besilate as the main active ingredient. Amlodipine Besilate belongs to category of drug known as calcium channel blockers. It is the most common drug used in the case of hypertension and chest pain. It prevents the influx of calcium in the smooth muscles and helps in supplying adequate amount of blood to the heart.
What is Amlopres used for?
Amlopres 5 mg is used to treat high blood pressure (hypertension) or chest pain (angina) and other conditions caused by coronary artery disease. This medication is for use in adults and children who are at least 6 years old.
How Amlopres does works?
Amlodipine decreases arterial smooth muscle contractility and subsequent vasoconstriction by inhibiting the influx of calcium ions through L-type calcium channels. Calcium ions entering the cell through these channels bind to calmodulin. Calcium-bound calmodulin then binds to and activates myosin light chain kinase (MLCK). Activated MLCK catalyses the phosphorylation of the regulatory light chain subunit of myosin, a key step in muscle contraction. Signal amplification is achieved by calcium-induced calcium release from the sarcoplasmic reticulum through ryanodine receptors. Inhibition of the initial influx of calcium decreases the contractile activity of arterial smooth muscle cells and results in vasodilation. The vasodilatory effects of amlodipine result in an overall decrease in blood pressure. Amlodipine is a long-acting CCB that may be used to treat mild to moderate essential hypertension and exertion-related angina (chronic stable angina). Another possible mechanism is that amlodipine inhibits vascular smooth muscle carbonic anhydrase I activity causing cellular pH increases which may be involved in regulating intracelluar calcium influx through calcium channels.
What are the side effects of Amlopres?
Amlopres 5 mg has significant side effects which are nausea and vomiting, dizziness, tired feeling, stomach pain, flushing, swelling of legs or ankles, lightheadedness, fast heartbeat, chest pain, pain in arms or shoulders, and fatigue, etc.
What medications interact with Amlopres?
It is important that you make known to your physician of all the medications you use as there are several medicines which are found to interact with this drug and are given below:
When should Amlopres not be used?
You should avoid Amlopres 5 mg if you are:
- Allergic to the drug
- Already pregnant or are planning to conceive
- Lactating mother
- Have other heart related problems
- Serious liver problem
- Severe nasal problems
- Having porphyria
- Have congestive heart failure
Please consult your physician before taking Amlopres.
How should Amlopres be used?
The medicine should be taken as prescribed by your physician. If possible, take the dose at a particular time each day; this will minimize the probability of a missed dose. Generally, one or two tablets are efficient to relieve you from the symptoms. Never overdose or under-dose, instead, take the prescribed dosage.
How long should you use Amlopres?
The medicine should be taken for as long as the doctor has recommended. It should taken orally. It is advised to use this medication exactly as per your doctor’s instructions.
Missed dose of Amlopres.
If you miss one dose of Amlopres 5 mg, you should not attempt to double your next dose. Just do follow the regular dosing schedule.
How should Amlopres be used?
Amlopres should be stored at controlled room temperature away from heat, moisture and temperature and in an airtight container with.