Arthrotec 50mg/200mcg
Available Dosages
| Description | Diclofenac sodium - misoprostol |
|---|---|
| SKU | 318 |
| Generic For | Arthrotec |
| Strength | 50mg/200mcg |
| Manufacturer | Pharmacia, UK |
| Active Ingredient | Diclofenac Sodium - Misoprostol |
Out Of Stock
Arthrotec 50mg/200mcg (Diclofenac Sodium - Misoprostol)
Diclofenac sodium - misoprostol
What is Arthrotec 50mg/200mcg used for?
Arthrotec 50mg/200mcg combines diclofenac Sodiumium 50mg, a nonsteroidal anti-inflammatory drug (NSAID), with misoprostol 200mcg, a prostaglandin that protects the stomach lining. It is prescribed to relieve pain, swelling, and stiffness from osteoarthritis and rheumatoid arthritis in patients who need an NSAID but are at high risk of developing gastric ulcers. The misoprostol component significantly reduces the risk of stomach and duodenal ulcers that can occur with NSAID use. Available from PremiumRxDrugs.com at competitive prices.
How does misoprostol in Arthrotec protect the stomach?
Misoprostol in Arthrotec works by binding to prostaglandin receptors in the stomach lining, stimulating mucus and bicarbonate secretion while reducing acid production. NSAIDs like diclofenac inhibit prostaglandins throughout the body, which relieves pain but also strips the stomach of its natural protective layer. The misoprostol in Arthrotec replenishes gastric prostaglandins locally, maintaining the protective mucus barrier even while diclofenac reduces prostaglandins elsewhere. This combination makes Arthrotec safer for the digestive tract than plain diclofenac alone.
What is the correct dosage of Arthrotec 50mg for arthritis?
The standard adult dose of Arthrotec 50mg/200mcg for osteoarthritis and rheumatoid arthritis is one tablet taken three or four times daily with food. Swallow the tablet whole—do not crush, break, or chew it, as this can release misoprostol too quickly and increase side effects. Your doctor may adjust the frequency based on how well you tolerate it. Never exceed the prescribed dose, and take it with food to further reduce any stomach upset. Always follow your physician's specific instructions for your condition.
Can Arthrotec 50mg cause diarrhea and stomach cramps?
Yes, diarrhea and abdominal cramping are among the most common side effects of Arthrotec, occurring in roughly 10–20% of users. These effects are caused primarily by the misoprostol component stimulating intestinal contractions and increasing fluid secretion. Taking Arthrotec with food and avoiding antacids containing magnesium can help reduce GI symptoms. Diarrhea usually appears early in treatment and often improves after the first few weeks. If diarrhea is severe or persistent, contact your doctor—a dose adjustment or alternative medication may be considered.
Is Arthrotec safe during pregnancy?
Arthrotec is strictly contraindicated in pregnancy. Misoprostol stimulates uterine contractions and can cause premature labor, birth defects, or miscarriage. Diclofenac can also harm fetal kidney development and cause premature closure of the ductus arteriosus, especially after 20 weeks of pregnancy. Women of childbearing age must use reliable contraception during Arthrotec therapy and should have a negative pregnancy test before starting. If pregnancy occurs while taking Arthrotec, stop the medication immediately and seek urgent medical advice.
How does Arthrotec 50mg compare to plain diclofenac 50mg for joint pain?
Both Arthrotec 50mg and plain diclofenac 50mg provide equivalent anti-inflammatory and analgesic relief for arthritis, as both contain the same 50mg dose of diclofenac Sodiumium. The key difference is gastrointestinal safety: studies show Arthrotec reduces the incidence of endoscopic gastric and duodenal ulcers by 65–80% compared to plain diclofenac, thanks to the built-in misoprostol. Arthrotec is specifically recommended for patients with a history of peptic ulcer disease, the elderly, or those on corticosteroids. Plain diclofenac is appropriate for lower-risk patients who want a simpler regimen.
Who should not take Arthrotec 50mg/200mcg?
Arthrotec is contraindicated in pregnant women (risk of miscarriage and fetal harm), patients with active peptic ulcer bleeding, those with severe kidney or liver disease, and individuals with a known allergy to diclofenac, aspirin, other NSAIDs, or misoprostol. It should also be avoided in patients with inflammatory bowel disease such as Crohn's disease or ulcerative colitis due to the misoprostol component. Caution is required in patients with cardiovascular disease, as diclofenac increases the risk of heart attack and stroke with long-term use.
Can I take Arthrotec with blood thinners or aspirin?
Combining Arthrotec with blood thinners like warfarin or antiplatelet drugs like aspirin significantly increases the risk of gastrointestinal bleeding and hemorrhage. Diclofenac inhibits platelet aggregation and the combination can be dangerous. Low-dose aspirin (for cardiovascular protection) may reduce Arthrotec's anti-inflammatory effectiveness. If you require both an anticoagulant and an NSAID, your doctor may prescribe a proton pump inhibitor or consider alternative pain management. Always inform your doctor about all medications before starting Arthrotec, including over-the-counter drugs.
How long does it take for Arthrotec 50mg to relieve joint pain?
Many patients notice an improvement in joint pain and morning stiffness within the first few days of starting Arthrotec 50mg. However, the full anti-inflammatory effect typically develops over 1–2 weeks of consistent use. Misoprostol's stomach-protective effects begin almost immediately. For chronic arthritis management, Arthrotec works best as a long-term treatment taken regularly rather than on an as-needed basis. Do not stop taking it abruptly without consulting your doctor, even if you feel better, as arthritis symptoms are likely to return.
What should I do if I miss a dose of Arthrotec?
If you miss a dose of Arthrotec, take it as soon as you remember—unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Never double up doses to compensate for a missed one, as this increases the risk of side effects including stomach irritation, cramping, and diarrhea. If you frequently forget doses, try setting a phone reminder or linking doses to a consistent daily activity like meals to improve adherence.
Is Arthrotec 50mg available without a prescription?
No, Arthrotec 50mg/200mcg is a prescription-only medication in the USA, UK, Australia, and most countries. It contains diclofenac, a regulated NSAID, and misoprostol, a drug that is tightly controlled due to its potential to cause abortion and uterine contractions. A physician's prescription is required to confirm appropriate use, screen for contraindications, and monitor for side effects such as cardiovascular events and gastrointestinal complications. PremiumRxDrugs.com requires a valid prescription for all orders of Arthrotec.
Why buy Arthrotec 50mg from PremiumRxDrugs.com?
PremiumRxDrugs.com offers genuine Arthrotec 50mg/200mcg sourced directly from licensed pharmaceutical manufacturers, with significant savings over local pharmacy prices in the USA, UK, and Australia. Customers benefit from secure ordering, discreet packaging, and reliable international shipping. The platform is trusted by thousands of arthritis patients managing long-term NSAID therapy. Dedicated customer support is available to assist with prescriptions, order tracking, and any product queries. Ordering from PremiumRxDrugs.com ensures you receive authentic medication at affordable prices without compromising quality.
Login
Sign Up
Login
Sign Up