Asacol 400mg
Available Dosages
| SKU | 652 |
|---|---|
| Generic For | Asacol |
| Strength | 400 mg |
| Manufacturer | Tillots Pharma |
| Active Ingredient | Mesalamine |
Out Of Stock
Asacol 400mg (Mesalamine)
Asacol 400mg contains Mesalamine as an active ingredient. This medication inhibits the function of chemical compound in the body that result in inflammation, damage of tissues, and diarrhea. Asacol is also prescribed to prevent the symptoms of ulcerative colitis from recurring.
What is Asacol 400mg used for?
Asacol 400mg is used for the treatment of mildly to moderately active ulcerative colitis in patients 5 years of age and older. Asacol is proven scientifically that its effective in reducing flares of moderately active active ulcerative colitis.
How does Asacol 400mg work?
Asacol 400mg contain active ingredient mesalazine. It is an anti-inflammatory chemical that inhibits the synthesis, by the walls of the intestine, of several chemicals that results inflammation, including prostaglandins and leukotrienes. Asacol tablets 400mg hinder the action of the enzymes cyclo-oxygenase, which synthesize prostaglandins, and lipoxygenase, which produces leukotrienes. It also stops the migration of inflammatory cells like macrophages into wall of intestine and performing the role of antioxidant, thus protecting the walls of the intestine from cell damage. Asacol tablets 400mg are coated specially with a resin to delay the release of mesalazine until it reaches the furthest part of the small intestine, so that it can act effectively the site of inflammation.
What does Asacol 400mg contain?
Asacol 400mg contains Mesalamine as main ingredient.
What are the side effects of Asacol 400mg?
As like other medications there are few side effects, which have been reported by patients after intake of Asacol 400mg includes:
- Mild stomach discomfort, gas
- Flu symptoms, runny nose
- Diarrhea, constipation
- Headache, dizziness
- Weakness
- Joint pain
This is not list of all side effects and others may occur. Please call your physician as soon as possible as any of the side effects persist longer.
What medications interact with Asacol 400mg?
The possible drug interactions with Asacol 400mg are:
- Amphotericin B
- Azathioprine or Mercaptopurine
- Pentamidine
- Tacrolimus
- An antibiotic - Capreomycin, Rifampin, Vancomycin
- Antiviral Drugs - Acyclovir, Adefovir, Cidofovir, Foscarnet
- Cancer medications - Aldesleukin, Carmustine, Cisplatin, Ifosfamide, Oxaliplatin, Streptozocin, Tretinoin
- NSAIDs (non-steroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
When should Asacol 400mg not be used?
Asacol 400mg should be avoided if you are allergic to the ingredients present in the medication. In such case you must consult with a certified physician. This medicine is not suggested to the people who are allergic to the composition of the medicine.
How should Asacol 400mg be taken?
It is advisable that patients take Asacol 400mg as prescribed by your physician. Do not alter the dose without consulting your physician, even if your condition seems to have improved. If you stop intake of this medication incorrectly there is a risk of dangerous withdrawal symptoms.
How long should you take Asacol 400mg?
Please continue taking Asacol 400mg for as long as your physician recommends.
Missed dose of Asacol 400mg
If you have missed to take a dose of Asacol 400mg, take it as soon as you remember. If it's almost time near your next dose, then skip the missed dose and go back to your regular schedule prescribed by physician. Never overdoses by taking two doses at same time.
How should Asacol 400mg be stored?
Keep Asacol 400mg out of the reach of children and pets. Keep the tablets in its original packet. Store it at room temperature away from moisture and heat.
What is Mesalamine and what condition does it treat?
Mesalamine is an anti-inflammatory medication used to treat ulcerative colitis, a chronic inflammatory bowel disease affecting the colon and rectum. Asacol 400mg contains mesalamine as its active ingredient and belongs to a class of drugs called aminosalicylates. This bowel disease treatment works by reducing inflammation in the intestinal lining, helping to control symptoms like abdominal pain, rectal bleeding, and diarrhea. The medication is also prescribed to maintain remission in patients who have previously experienced flare-ups of ulcerative colitis.
How does Mesalamine work in the body?
Mesalamine works locally in the gastrointestinal tract by blocking the production of certain chemicals that cause inflammation in the bowel lining. Asacol 400mg uses a special delayed-release coating that allows the mesalamine to reach the colon intact, where it's needed most. This aminosalicylate medication inhibits prostaglandins and leukotrienes, substances that trigger inflammatory responses. By reducing inflammation directly at the site of ulcerative colitis, this IBD treatment helps heal damaged intestinal tissue and prevents further flare-ups without suppressing your entire immune system like some other medications.
How long does Asacol 400mg take to work?
Asacol 400mg typically begins working within three to six weeks of starting treatment, though some patients notice improvement in ulcerative colitis symptoms earlier. The mesalamine in this delayed-release medication needs time to reduce inflammation gradually in the intestinal lining. For acute flare-ups, you might see reduced bleeding and diarrhea within two weeks, but complete healing often requires two to three months of consistent use. Response times vary based on disease severity and individual factors. Patience is important with this inflammatory bowel disease medication, as gradual healing produces more sustainable results.
When and how should I take Asacol 400mg?
Take Asacol 400mg exactly as prescribed, typically three times daily with or without food. Swallow the tablets whole—never crush, chew, or break them, as the delayed-release coating ensures mesalamine reaches your colon effectively. Taking this ulcerative colitis medication at evenly spaced intervals throughout the day maintains consistent anti-inflammatory levels. Most patients take doses morning, afternoon, and evening. Stay well-hydrated while using this aminosalicylate treatment. Always follow your healthcare provider's specific dosing instructions, as they may adjust based on your condition severity and response to treatment.
Is Asacol 400mg safe for long-term use?
Asacol 400mg is generally considered safe for long-term maintenance therapy in ulcerative colitis patients. Many people take mesalamine for years to keep their inflammatory bowel disease in remission with minimal side effects. This aminosalicylate has a well-established safety profile compared to stronger immunosuppressants. However, ongoing monitoring through periodic blood tests and kidney function checks helps ensure continued safety during extended use. Long-term mesalamine treatment significantly reduces flare-up frequency and helps prevent colorectal complications associated with chronic ulcerative colitis, making the benefits substantial for most patients requiring ongoing IBD management.
Can I take Asacol 400mg with other medicines?
Asacol 400mg can typically be taken alongside many common medications, but certain drug interactions require caution. Mesalamine may interact with azathioprine, 6-mercaptopurine, and some nonsteroidal anti-inflammatory drugs that could worsen ulcerative colitis symptoms. Antacids may affect how this delayed-release formulation dissolves, so separate doses by at least two hours. This aminosalicylate generally works well with other inflammatory bowel disease treatments when medically supervised. Always inform your healthcare provider about all medications, supplements, and vitamins you're taking to avoid potential interactions and ensure optimal effectiveness of your ulcerative colitis therapy.
How does Asacol 400mg compare to similar medicines in its class?
Asacol 400mg stands out among mesalamine formulations due to its pH-dependent delayed-release coating that dissolves at pH 7 or higher, targeting the terminal ileum and colon. Compared to Pentasa, which releases throughout the digestive tract, or Lialda, a once-daily option, Asacol offers targeted delivery for ulcerative colitis specifically affecting the lower bowel. All aminosalicylate medications share the same active ingredient but differ in release mechanisms and dosing frequency. Your gastroenterologist will recommend the best mesalamine formulation based on where inflammation occurs in your inflammatory bowel disease and your lifestyle preferences.
Is generic Mesalamine as effective as branded Asacol 400mg?
Generic mesalamine contains the same active ingredient and therapeutic strength as branded Asacol 400mg, meeting strict regulatory standards for bioequivalence and effectiveness in treating ulcerative colitis. Both versions deliver the aminosalicylate to your colon using delayed-release technology. The main differences lie in cost and sometimes inactive ingredients. Many patients successfully manage their inflammatory bowel disease with generic formulations at significantly lower prices. However, some individuals respond differently to specific coatings or excipients. Most healthcare providers consider generic mesalamine an equally effective and more affordable option for long-term ulcerative colitis management.
Why do patients choose PremiumRxDrugs for Asacol 400mg?
Patients choose PremiumRxDrugs for Asacol 400mg for the combination of competitive pricing, medication authenticity, and convenience. As a licensed pharmacy, we are committed to stocking mesalamine directly from manufacturers to ensure quality for your ulcerative colitis treatment. The easy reorder system helps patients maintain consistent inflammatory bowel disease management without interruption. Discreet worldwide shipping protects your privacy, while multiple delivery options, including free shipping choices, provide flexibility. With over a decade of service to customers across the USA, UK, Australia, Canada, and beyond, PremiumRxDrugs has built trust through reliable service and authentic aminosalicylate medications at prices that make long-term treatment affordable.
What are the common side effects of Mesalamine?
Common side effects of mesalamine include headache, nausea, abdominal cramping, gas, and occasionally diarrhea—ironically similar to ulcerative colitis symptoms themselves. Some patients experience mild hair loss or dizziness while taking this aminosalicylate medication. Most side effects are temporary and resolve as your body adjusts to the inflammatory bowel disease treatment. Less common but important reactions include rash, fever, or worsening abdominal pain, which warrant medical attention. Serious side effects like kidney problems or allergic reactions are rare. The majority of people tolerate mesalamine well, experiencing minimal issues during their ulcerative colitis therapy.
Who should avoid taking Mesalamine?
People with known allergies to mesalamine, salicylates (like aspirin), or sulfasalazine should avoid this aminosalicylate medication. Those with severe kidney or liver disease require careful evaluation before starting this ulcerative colitis treatment, as mesalamine is processed through these organs. Patients with certain heart conditions, including myocarditis or pericarditis potentially linked to previous mesalamine use, should not take this inflammatory bowel disease medication. Children under two years typically shouldn't use this treatment. Pregnant or breastfeeding women need medical guidance, though mesalamine is often considered relatively safe. Always disclose your complete medical history before beginning any ulcerative colitis therapy.
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