Bactrim DS (800 160) mg or Septran DS
| SKU | 2003 |
|---|---|
| Generic For | Septra DS |
| Strength | 160mg |
| Manufacturer | Piramal Enterprises Ltd. |
| Active Ingredient | Sulphamethoxazole + Trimethoprim |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.27 | US$ 8.00 | |||
|
|||||
| 60 Tablet/s | US$ 0.20 | US$ 12.0025%US$ 16.00 | |||
|
|||||
| 90 Tablet/s | US$ 0.17 | US$ 15.0037%US$ 24.00 | |||
|
|||||
Bactrim DS (800 160) mg or Septran DS – Affordable Septra DS Alternative
Bactrim DS is a combination drug that contains two active ingredients namely Sulphamethoxazole and Trimethoprim. The medication is specially formulated for treating certain infections caused by the bacteria. Sulphamethoxazole belongs to a category of drugs known as sulfa drugs. The combination medication is an antibiotic medication, which is useful in treating a variety of infections including urinary tract infections.
What is Bactrim DS used for?
Bactrim DS is indicated for the treatment of following health conditions:
- Bronchitis
- Otitis media
- Urinary tract infections
- Pneumocystis jirovecii pneumonia (PCP)
- Traveler’s diarrhea
It is also useful in preventing PCP in HIV-positive patients.
How does Bactrim DS work?
The combination drug exerts bactericidal against susceptible bacteria and works by inhibiting the metabolism of folic acid in bacteria at two different points.
What does Bactrim DS contain?
Bactrim DS comprise of Sulphamethoxazole and Trimethoprim, which works straight away; reduces symptoms of bacterial infections. However, the medicine is not used for treating viral infections like cold and flu.
What medications interact with Bactrim DS?
Please inform your health care specialist about the following medications:
- Phenytoin
- Sulfonylureas
- Pioglitazone
- Digoxin
- Warfarin
- Thiazide diuretics
- Methotrexate
- Repaglinide
- Rosiglitazone
- Cyclosporine
- ACE inhibitors
- Leucovorin
- Tricyclic antidepressants
What are the side effects of Bactrim DS?
- Genitouterine disorders- crystalluria
- Gastrointestinal issues- nausea, stomatitis, hepatic necrosis, hepatitis, cholestatic jaundice, pseudomembranous colitis, vomiting, diarrhea
- Hematological issues- Aplastic anemia, leukopenia, thrombocytopenia, megaloblastic anemia, haemolytic anemia, agranulocytosis
- F and E disorders- hyponatremia, hyperkalemia
- Central nervous system disorders- hallucinations, insomnia, kernicterus in neonates, headache, fatigue, mental depression
- Dermatological issues- toxic epidermal necrolysis, photosensitivity, stevens-johnson syndrome, erythema multiforme
- Endoskeletal disorders- hypoglycemia
- Cardiovascular system disorders- hypotension
- Miscellaneous issues- fever
How should Bactrim DS be used
The combination drug is supplied in the form of tablets for oral administration. Depending on the condition of the patient, the health care specialist will determine the dose. Avoid exceeding the suggested dose.
A patient is not supposed to give the medicine to anyone else who is suffering from the same symptoms. If the condition does not improve till the prescribed period, please contact your healthcare specialist.
When should Bactrim DS not be used?
- Bactrim DS should not be used in patients who are allergic to any of the ingredients of the medication.
- It is not suitable for patients with a background of drug-induced immune thrombocytopenia due to Trimethoprim or Sulphonamide.
- The use of the medicine is contraindicated in patients with renal and hepatic insufficiency.
- It should not be used during pregnancy.
- Lactating mothers are advised not to take the medicine.
- The medicine should not be given to children less than two years of age.
Exercise caution while using this medication in the following conditions:
- Mild to moderate renal and hepatic impairment
- Glucose-6 dehydrogenase deficiency.
- HIV positive patients
How long should Bactrim DS be used?
Treatment with Bactrim DS may be continued indefinitely as long as it is effective and as long as no unwanted effects develop. Your health care specialist will tell you how long you need to take this medicine. Follow his/her instructions if you want to get the most out of it.
Missed dose of Bactrim DS
If you missed a dose of Bactrim DS, take it as soon you remember and go back to your regular dosing regimen. If the time to take the next dose is close enough, leave the missed dose and take the next dose on time. Avoid compensating by taking two doses at the same time.
How should Bactrim DS be stored?
Keep the tablets in its original packet to protect from light. Store it at controlled room temperature. Place it at a place where children cannot reach.
What is Sulphamethoxazole + Trimethoprim and what condition does it treat?
Sulphamethoxazole + Trimethoprim is a combination antibiotic medication sold under brand names like Bactrim DS (800 160) mg and Septran DS. This dual-action antimicrobial drug treats bacterial infections including urinary tract infections (UTIs), respiratory tract infections, ear infections, traveller's diarrhea, and certain types of pneumonia. The combination works as a sulfonamide antibiotic that targets bacteria causing infection throughout the body. Doctors commonly prescribe this antibacterial medicine for both acute infections and prevention of recurring UTIs in susceptible patients.
How does Sulphamethoxazole + Trimethoprim work in the body?
Sulphamethoxazole + Trimethoprim works through a synergistic dual-blocking mechanism that stops bacterial growth and reproduction. Sulphamethoxazole inhibits bacterial production of dihydrofolic acid, while Trimethoprim blocks the next step by preventing conversion to tetrahydrofolic acid. Bacteria need folic acid to produce DNA and multiply. By blocking two sequential steps in this metabolic pathway, Bactrim DS (800 160) mg or Septran DS effectively starves bacteria of essential nutrients. This combination antibiotic therapy proves more effective than either component alone, reducing bacterial resistance and improving infection clearance rates.
How long does Bactrim DS (800 160) mg or Septran DS take to work?
Bactrim DS (800 160) mg or Septran DS typically begins working within one to four hours after the first dose, with peak blood concentration of the active ingredients Sulphamethoxazole and Trimethoprim reached in this timeframe. However, noticeable symptom improvement for infections like UTIs usually occurs within 24 to 48 hours of starting treatment. Complete infection resolution requires finishing the full antibiotic course, typically five to fourteen days depending on infection severity and type. For respiratory or more serious bacterial infections, symptom relief may take three to five days while the antimicrobial medication eliminates pathogens.
When and how should I take Bactrim DS (800 160) mg or Septran DS?
Take Bactrim DS (800 160) mg or Septran DS exactly as prescribed, typically one tablet twice daily (every 12 hours) with a full glass of water. This antibiotic combination can be taken with or without food, though taking it with meals may reduce stomach upset. Drink plenty of fluids throughout treatment to prevent crystal formation in urine. Swallow tablets whole without crushing. Maintain consistent timing to keep steady blood levels of Sulphamethoxazole and Trimethoprim. Complete the entire prescribed course even if symptoms improve early, as stopping prematurely can lead to antibiotic resistance and infection recurrence.
Is Bactrim DS (800 160) mg or Septran DS safe for long-term use?
Bactrim DS (800 160) mg or Septran DS is generally prescribed for short-term infection treatment lasting five to fourteen days. Long-term or prophylactic use may be appropriate for specific conditions like preventing recurring urinary tract infections or Pneumocystis pneumonia in immunocompromised patients. Extended use of this sulfonamide antibiotic requires regular medical monitoring including blood tests to check for blood cell changes, liver function, and kidney health. Prolonged Sulphamethoxazole + Trimethoprim therapy carries increased risks of side effects and potential bacterial resistance development, so healthcare providers carefully weigh benefits against risks for ongoing treatment protocols.
Can I take Bactrim DS (800 160) mg or Septran DS with other medicines?
Bactrim DS (800 160) mg or Septran DS can interact with several medications including warfarin (increasing bleeding risk), methotrexate, diabetes medications, diuretics, phenytoin, and certain antidepressants. This antibiotic combination may also interact with blood pressure medicines and potassium supplements. Always inform your healthcare provider about all prescription drugs, over-the-counter medicines, vitamins, and herbal supplements you're taking before starting Sulphamethoxazole + Trimethoprim therapy. Your doctor may adjust dosages or monitor you more closely for adverse interactions. Avoid combining this antimicrobial with other sulfonamide antibiotics to prevent compounded side effects.
How does Bactrim DS (800 160) mg or Septran DS compare to similar medicines in its class?
Bactrim DS (800 160) mg or Septran DS offers unique advantages compared to single-agent antibiotics like amoxicillin or ciprofloxacin. The dual-action combination of Sulphamethoxazole and Trimethoprim provides broader bacterial coverage and reduced resistance development. Unlike fluoroquinolone antibiotics, this sulfonamide combination has fewer musculoskeletal side effects. Compared to nitrofurantoin for UTIs, Bactrim covers more infection types including respiratory and skin infections. The medication's twice-daily dosing and cost-effectiveness make it preferable to some newer antimicrobials. However, allergy rates are higher with sulfa-based antibiotics, making alternatives necessary for sulfa-sensitive patients.
Is the generic Sulphamethoxazole + Trimethoprim as effective as branded versions?
Generic Sulphamethoxazole + Trimethoprim is therapeutically equivalent to branded versions like Bactrim DS (800 160) mg or Septran DS, containing identical active ingredients in the same strengths. Regulatory agencies in the USA, UK, Canada, and Australia require generics to meet strict bioequivalence standards, ensuring they work identically in the body. The same antimicrobial effectiveness, absorption rates, and infection-fighting capabilities apply to both generic and brand-name versions. The primary differences are inactive ingredients, appearance, and cost—generic antibiotic combinations typically cost significantly less while delivering the same clinical outcomes for bacterial infections.
Why do patients choose PremiumRxDrugs for Bactrim DS (800 160) mg or Septran DS?
Patients trust PremiumRxDrugs for Bactrim DS (800 160) mg or Septran DS because of our decade-plus reputation for reliability and authenticity. The licensed pharmacy offers competitive pricing on this essential antibiotic while guaranteeing manufacturer-sourced Sulphamethoxazole + Trimethoprim medications only. Discreet packaging protects privacy, while worldwide shipping efficiently serves customers across the USA, the UK, Australia, and Canada. Our easy prescription management and reorder system simplifies ongoing antimicrobial treatment needs. Customers appreciate transparent pricing, responsive support, and the convenience of having quality infection-fighting medications delivered reliably without compromising on pharmaceutical standards or service quality.
What are the common side effects of Sulphamethoxazole + Trimethoprim?
Common side effects of Sulphamethoxazole + Trimethoprim include nausea, vomiting, loss of appetite, and mild diarrhea as your body adjusts to this antibiotic combination. Some patients experience skin sensitivity to sunlight, requiring sun protection during treatment. Headache, dizziness, and mild skin rash may occur occasionally. Less common but more serious reactions include severe allergic responses, blood disorders, liver problems, or severe skin reactions like Stevens-Johnson syndrome. Contact your healthcare provider immediately if you develop fever, sore throat, unusual bruising, yellowing skin, severe rash, or persistent diarrhea while taking this antimicrobial medication.
Who should avoid taking Sulphamethoxazole + Trimethoprim?
Individuals with known sulfa drug allergies should avoid Sulphamethoxazole + Trimethoprim as allergic reactions can be severe. This antibiotic combination is contraindicated for people with severe kidney disease, liver damage, certain blood disorders like megaloblastic anemia, or folate deficiency. Pregnant women near term, nursing mothers, and infants under two months shouldn't use this medication due to potential complications. Patients with glucose-6-phosphate dehydrogenase deficiency face increased hemolytic anemia risk. Those taking specific medications like dofetilide should avoid this antimicrobial due to dangerous interactions. Always disclose your complete medical history before starting any sulfonamide antibiotic therapy.




Login
Sign Up
Login
Sign Up