Cardivas 3.13mg
Available Dosages
| SKU | 190 |
|---|---|
| Generic For | Coreg |
| Strength | 3.125mg |
| Active Ingredient | Carvedilol |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.15 | US$ 4.50 | |||
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| 60 Tablet/s | US$ 0.15 | US$ 9.00 | |||
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| 90 Tablet/s | US$ 0.13 | US$ 12.0011%US$ 13.50 | |||
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Cardivas 3.13mg (Carvedilol) – Affordable Coreg Alternative
Cardivas 3.125 mg is an adjunctive therapy for treating patients with moderate to severe stable chronic heart failure. It is also used to manage hypertension (high blood pressure) and prophylactically treat stable angina. The medicine's active ingredient is Carvedilol, which is categorized under the class of medications known as beta blockers. These medications are believed to slow the heart rate, causing the heart to beat normally and reducing blood pressure.
Cardivas 3.13mg is contraindicated in the following conditions/situations.
- Hypersensitivity to Carvedilol or any other ingredients in the medicine.
- Fluid retention
- Obstructive airway disease (breathing problems because of narrowing or obstruction of the airways in conditions like asthma, COPD, and chronic bronchitis), liver dysfunction, unstable decompensated heart failure
- Prinzmetal's angina (Chest pain that happens when an individual is resting)
- Sick sinus syndrome
- Severe hypotension ( too low blood pressure)
- Metabolic acidosis
- Severe bradycardia (heart rate slower than normal)
- Cardiogenic shock
- Alzheimer's s disease
- Alcoholism/drug abuse
- Severe peripheral arterial circulatory disturbances
- Concomitant intravenous therapy with verapamil or diltiazem
- Galactosaemia, Lactose insufficiency, or glucose/galactose malabsorption syndrome
It is not known whether the medication is excreted in breast milk. Therefore, breastfeeding is not recommended while receiving Cardivas 3.125mg. No research studies have been conducted on the effect of medicine on a patient's fitness to drive a vehicle or operate complex machinery.
Furthermore, because of the medicine's reactions, like dizziness and tiredness, a patient's ability to drive or operate complex machines may be affected. This particularly happens during the initial days of the treatment and when used in combination with alcohol. There are insufficient studies on the effects of medicine on pregnancy. Therefore, it should not be used during pregnancy unless the potential benefits outweigh the risks. Cardivas is not meant for use in children below 18 years of age as there is insufficient data available on the effectiveness and safety of this medicine. Older adults may be more susceptible to the effects of this medicine and should be carefully monitored.
Certain medications may interfere with the working of Carvedilol. These may include cimetidine, digoxin, clonidine, diltiazem, verapamil, anti-diabetic drugs, cyclosporine, asthma medications, aspirin, and other pain relivers, fluoxetine, and other medicines to help lower blood pressure, etc. There may be other medications that may interact with Cardivas; consult your doctor if you have any doubts regarding drug interactions.
Like all medications, this medicine can contribute to unwanted effects, although not everybody who uses it gets it. If any of the following occurs, discontinue treatment and visit the emergency department at your nearest hospital:
- An allergic reaction (skin rash or hives; swelling of the skin on the lips, face, or neck, which ultimately leads to trouble breathing
- Inflammatory skin eruptions are a serious condition accompanied by blistering of the skin, eyes, mouth, and genitals.
These are serious but rare side effects. A patient may require immediate medical attention or hospitalization. Adverse effects are less likely to affect patients being treated for angina or hypertension than patients being treated for heart failure.
Side effects that occur in patients being treated for heart failure:
Very common ones include dizziness, headache, low blood pressure, lack of muscle strength and weakness, heart failure, lungs disease, depression, reduced blood cells, increased blood cells, slow heartbeat, problems with your vision, changes in blood sugar levels, abnormal accumulation of fluid in body causing swelling of fingers, ankles, feet or penis, etc.
Side effects that occur in patients being treated for angina or hypertension include breathing problems, dizziness, tiredness, dry eye, tiredness, slow heart rate, asthma, stomach pain, a rapid drop of blood pressure, mild headache, loose stools, feeling unwell, fluid accumulation in lungs, and urinary tract infections, indigestion, pain in hand and feet, pain in tummy, fluid accumulation in lungs, a rapid drop of blood pressure when standing up, feeling unwell, generalized pain, etc.
It is always suggested that medicine be used only under the supervision of a healthcare provider. Cardivas 3.125mg is available for oral use. The tablets should be swallowed, preferably with a glass full of water, without crushing, breaking, or chewing the tablet. It should be taken with food as this helps slow down absorption and reduces the incidence of low blood pressure upon standing.
Liver or kidney problems: Doctors usually prescribe a low dose to patients with liver or kidney problems.
What is carvedilol 3.125 mg used for?
Carvedilol 3.125 mg is the initial starting dose of a combined alpha and beta adrenergic blocker used to treat chronic heart failure, hypertension, and left ventricular dysfunction after a heart attack. Cardivas 3.13mg — the generic for Coreg — blocks both alpha-1 receptors (causing vaSodiumilation) and beta-1 and beta-2 receptors (reducing heart rate and cardiac workload). The 3.125 mg dose allows the body to adjust before gradual dose escalation to therapeutic levels.
How does carvedilol work differently from standard beta-blockers?
Unlike selective beta-blockers, carvedilol blocks both beta-1 and beta-2 adrenergic receptors as well as alpha-1 receptors. The alpha-1 blockade causes peripheral vaSodiumilation, reducing afterload on the heart. This combined blockade reduces heart rate, lowers blood pressure, and decreases myocardial oxygen demand — while also counteracting the vasoconstriction that would occur with beta-blockade alone. This multifaceted action makes carvedilol particularly effective in heart failure management.
When and how should carvedilol 3.125 mg be taken?
Carvedilol 3.125 mg is taken twice daily with food — taking it with meals slows absorption and reduces the risk of dizziness or orthostatic hypotension. Take it consistently morning and evening. Heart failure guidelines recommend starting at this low dose and doubling every 2 weeks as tolerated, up to a target dose of 25 mg twice daily. Never stop carvedilol abruptly — sudden discontinuation can trigger rebound hypertension or worsening angina.
How long does it take carvedilol 3.125 mg to show heart failure benefit?
At the 3.125 mg starting dose, carvedilol's primary goal is tolerability establishment rather than maximum benefit. Blood pressure and heart rate reductions are noticeable within the first 1–2 hours of each dose. Meaningful clinical heart failure benefits — reduced hospitalisation, improved exercise tolerance, and ejection fraction improvement — emerge over 3–6 months as the dose is gradually titrated upward. The starting dose itself provides modest haemodynamic benefit while the body adapts to the medication.
Is carvedilol 3.125 mg safe to start in elderly patients with heart failure?
The 3.125 mg starting dose is specifically designed for cautious initiation in elderly and frail patients with heart failure. Starting low and titrating slowly is essential, as carvedilol can initially worsen fluid retention (which is managed by optimising diuretic therapy) and cause dizziness due to alpha-blockade-mediated vaSodiumilation. Elderly patients should be monitored for orthostatic hypotension, bradycardia, and weight changes during dose escalation. Medical supervision during titration is strongly recommended.
Can carvedilol be taken with ACE inhibitors or ARBs for heart failure?
Yes — carvedilol is routinely combined with ACE inhibitors (like lisinopril) or ARBs (like valsartan) as part of guideline-directed medical therapy for heart failure with reduced ejection fraction. This combination addresses different pathophysiological mechanisms — neurohormonal blockade via beta/alpha blockade plus the renin-angiotensin system — and has been shown to significantly reduce heart failure mortality and hospitalisation. Blood pressure and potassium should be monitored during co-administration.
How does Cardivas 3.13mg compare to Coreg (carvedilol) from a US pharmacy?
Cardivas 3.13mg is a generic version of Coreg (carvedilol 3.125 mg), manufactured to bioequivalence standards. Both contain the same active ingredient at the same dose and deliver identical pharmacological effects. The key difference is price — branded Coreg carries a significantly higher price in US pharmacies than generic carvedilol. Cardivas 3.13mg offers the same heart failure and hypertension management at a fraction of the cost.
Is carvedilol better than metoprolol for heart failure?
Carvedilol and metoprolol succinate (Toprol XL) are both proven to reduce mortality in heart failure, but carvedilol's additional alpha-1 blocking action provides vaSodiumilatory benefit alongside beta-blockade. A landmark trial (COMET) suggested carvedilol may reduce all-cause mortality more than immediate-release metoprolol tartrate, though comparisons with metoprolol succinate extended-release are less clear-cut. Both are recommended in heart failure guidelines; choice often depends on tolerability and comorbidities.
Where can I buy Cardivas 3.13mg online?
Cardivas 3.13mg is available at PremiumRxDrugs.com, a licensed pharmacy delivering to the USA, UK, Australia, and worldwide. They carry authentic manufacturer-sourced carvedilol at highly competitive prices — significantly lower than Coreg — with free shipping on qualifying orders and discreet packaging. Heart failure patients who require regular carvedilol refills benefit from the pharmacy's easy prescription upload and reorder management system.
Can I order carvedilol 3.125 mg from an international pharmacy?
Yes. PremiumRxDrugs.com ships carvedilol — including Cardivas 3.13mg — internationally to the USA, UK, Australia, and many other countries. As a trusted pharmacy for over a decade, they ensure authentic, manufacturer-verified carvedilol reaches patients at competitive prices. Discreet packaging and free worldwide shipping make this a reliable option for heart failure patients seeking cost-effective, continuous access to their cardiac medication.
What side effects should I watch for when starting carvedilol 3.125 mg?
When initiating carvedilol 3.125 mg, the most common side effects are dizziness, fatigue, low blood pressure (particularly postural), and a slowed heart rate. Some patients experience fluid retention or worsening shortness of breath in the first weeks — this often settles with diuretic optimisation rather than stopping carvedilol. Hypoglycaemia may be masked in diabetic patients on insulin. Rise slowly from chairs and beds to minimise dizziness from the alpha-blocking vaSodiumilatory effect.
Who should not take carvedilol?
Carvedilol is contraindicated in patients with bronchial asthma or severe COPD (beta-2 blockade can trigger bronchospasm), decompensated heart failure requiring IV support, second- or third-degree AV block without a pacemaker, severe bradycardia, and cardiogenic shock. Patients with Raynaud's phenomenon or severe peripheral vascular disease should use carvedilol with caution. Always inform your cardiologist of all respiratory conditions before starting this medication.
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