SKU	248
Generic For	Dycip TZ
Strength	500 mg + 600 mg
Active Ingredient	Ciprofloxacin Tinidazole

Ciplox TZ 500/600 mg – Affordable Dycip TZ Alternative

Ciplox TZ 500 mg 600 mg

Ciplox TZ 500 mg 600 mg is indicated for treating many infections. It contains the active ingredients-Ciprofloxacin and Tinidazole. Ciprofloxacin is a synthetic broad-spectrum antimicrobial agent, and Tinidazole is a nitroimidazole antimicrobial agent. Both effectively treat gynaecological infections, teeth and urine infections, and diarrhoea in adult patients.

How to use Ciplox TZ 500 mg 600 mg?

Ciplox TZ should be taken an hour or two hours after meals with a glass of water.

For adults, the usual recommended dose is one tablet twice daily for 5 to 10 days, depending on severity and response. It is not recommended for children. Any calcium you take as part of a meal will not seriously affect uptake, so your diet cannot interfere with the absorption of Ciplox TZ. However, dairy products or calcium-fortified orange juice are the exceptions.

If you have further questions, please ask your doctor.

What are the Precautions for Ciplox TZ?

Concurrent usage with Tizanidine is contraindicated.
Ciplox TZ is contraindicated in patients with hypersensitivity to Ciprofloxacin, Tizanidine, or any product’s components.
The medicine should not be used in patients with a previous history of hypersensitivity to Tinidazole or another nitroimidazole.
It should not be used during the first trimester of pregnancy and in nursing mothers.

Before you take Ciplox TZ 500 mg 600 mg:

If you are hypersensitive to Ciprofloxacin, Tinidazole, or any other ingredients of the medicine. Signs and symptoms of an allergic reaction include a rash, breathing problems, wheezing, lips, face, throat, or tongue swelling.
If you have central nervous system disorder, including epilepsy
If you have a blood disorder or a history of blood disorders
If you are initially thirteen weeks pregnant, trying to become pregnant, or breastfeeding.

Speak to your doctor before taking Ciplox TZ if any of the following applies to you:

If you have epilepsy or are at risk of fits
If you have ever had kidney problems. Your doctor may need to be adjusted
If, during the treatment, you develop neurological signs such as vertigo, dizziness, and difficulty in controlling movements
If you have a history of tendon problems at the time of previous treatment with an antibiotic drug like Ciprofloxacin.
If you have diabetes because you may experience a risk of hypoglycemia with Ciplox TZ
If you have a muscle weakness called myasthenia gravis, symptoms may worsen.
If you have heart disease, exercise caution when using the medicine if you have a salt imbalance in the blood, have a weak heart, have a history of heart attack, you are female or elderly.

Also, let your doctor know if you are taking any of the following medicines:

Metoclopramide
Probenecid
Methotrexate
Theophylline
Tizanidine
Olanzapine
Cyclosporin
Ropinirole
Phenytoin
Other medicines can alter heart rhythm.

What are the Side effects of Ciplox TZ ?

The common side effects of Ciplox TZ include nausea, loss of appetite, vomiting, diarrhoea, stomach pain, cramps, headache, vertigo, skin rash, or itching. Most of these side effects are mild and do not cause any problems. If you get any side effects other than those mentioned in this information guide, immediately contact your doctor.

Precautions

Dosage Instructions

Side Effects

How to Use

Infographics

FAQ

What is Ciplox TZ 500/600mg used for?

Ciplox TZ is a combination tablet containing ciprofloxacin (500mg) and tinidazole (600mg). It combines a broad-spectrum antibiotic (ciprofloxacin) that covers a wide range of bacteria with an antiprotozoal and anti-anaerobic medicine (tinidazole) that treats infections caused by anaerobic bacteria (bacteria that live without oxygen) and parasites. It is used for mixed bacterial and protozoal infections, including gastrointestinal infections, abdominal infections, pelvic inflammatory disease (PID), and complicated urinary or gynaecological infections where both aerobic and anaerobic organisms may be involved.

Who should not take Ciplox TZ?

Ciplox TZ should not be taken by anyone allergic to ciprofloxacin, other fluoroquinolones, tinidazole, metronidazole, or related medicines. It should be avoided in people with epilepsy, severe liver disease, significant kidney disease, blood disorders, or a history of central nervous system (CNS) disease. It is contraindicated in pregnancy — particularly during the first trimester — and in breastfeeding women. Children and teenagers should not use this combination tablet. Always provide your complete medical and allergy history to your doctor before starting this medicine.

What is the usual dose of Ciplox TZ for adults?

The standard adult dose is one tablet taken twice daily, with or after a meal. Treatment typically lasts 5 to 7 days for most infections, though your doctor may prescribe a different duration based on the infection type and severity. This combination tablet is generally used for short courses — long-term use is not recommended. Always complete the full prescribed course and do not stop early because symptoms have improved. Follow your doctor's instructions precisely and report any side effects promptly.

Should Ciplox TZ be taken with or without food?

Ciplox TZ should be taken with or after a meal. The tinidazole component in particular can cause significant nausea and stomach upset when taken on an empty stomach, and food substantially reduces this. Taking the tablet with a full glass of water is recommended. As with all ciprofloxacin-containing products, avoid taking it at the same time as dairy products, antacids, or iron and mineral supplements — these reduce ciprofloxacin absorption. Separate these by at least 2 hours before or 6 hours after your dose.

Is Ciplox TZ safe during pregnancy or breastfeeding?

No — Ciplox TZ is not recommended during pregnancy, particularly in the first trimester. Both ciprofloxacin (due to potential effects on foetal cartilage development) and tinidazole (due to potential effects on developing cells in early pregnancy) are generally avoided. If you are pregnant and develop an infection requiring treatment, your doctor will choose a pregnancy-safe antibiotic combination. Ciplox TZ should also not be used while breastfeeding, as both components pass into breast milk. If taking this medicine, breastfeeding must be interrupted during treatment and for at least 3 days after the last dose.

Can I drink alcohol while taking Ciplox TZ?

Absolutely not — alcohol must be strictly avoided while taking Ciplox TZ and for at least 72 hours (3 days) after the last tablet. The tinidazole component causes a severe reaction when combined with alcohol — known as a disulfiram-like reaction. This can cause intense flushing (a hot, red face), severe headache, rapid heartbeat, nausea, vomiting, and in severe cases, a significant drop in blood pressure. This reaction can be very distressing and potentially dangerous. Avoid all alcohol-containing products including alcoholic drinks, mouthwashes, and some cough syrups during this period.

How does Ciplox TZ work, and why use a combination tablet?

Ciprofloxacin kills a broad range of bacteria by disrupting their ability to replicate their DNA. Tinidazole targets anaerobic bacteria (which thrive in low-oxygen environments like the gut, pelvis, and abdominal cavity) and protozoa (microscopic parasites). Many gastrointestinal, pelvic, and abdominal infections involve a mixture of aerobic bacteria (which ciprofloxacin covers) and anaerobic bacteria or protozoa (which tinidazole covers). The combination in a single tablet provides comprehensive coverage against this mixed microbiological environment, making treatment more effective and convenient than taking two separate medicines.

Does Ciplox TZ interact with other medicines?

Ciplox TZ has a complex interaction profile. Ciprofloxacin raises theophylline (asthma medicine) to toxic levels — avoid this combination. It enhances the effect of warfarin (bleeding risk). NSAIDs increase seizure risk when combined with ciprofloxacin. Tinidazole interacts with alcohol (severe reaction), warfarin (increased anticoagulant effect), lithium (raised lithium levels), and disulfiram (risk of psychotic reactions). Always give your doctor and pharmacist a complete list of every medicine, supplement, and herbal product you are taking before starting Ciplox TZ.

What should I do if I miss a dose of Ciplox TZ?

Take the missed dose as soon as you remember, with food. If the next dose is nearly due, skip the missed tablet and continue your normal schedule. Do not take two tablets together. Ciplox TZ is typically prescribed for short courses of 5–7 days, so consistent dosing throughout the full course is particularly important. Missing a dose in a short course can meaningfully affect the overall antibiotic coverage achieved. Setting twice-daily phone reminders linked to your main meals is a practical way to ensure you do not miss any doses.

Can Ciplox TZ be used for intestinal infections?

Yes — Ciplox TZ is often prescribed for gastrointestinal infections where both aerobic bacteria and anaerobic organisms or protozoa may be involved. Ciprofloxacin covers common intestinal bacteria like E. coli, Salmonella, Shigella, and Campylobacter. Tinidazole covers Giardia (a protozoal parasite causing giardiasis), Entamoeba histolytica (which causes amoebiasis), and anaerobic bacteria. This broad combined coverage makes Ciplox TZ useful for traveller's diarrhoea, dysentery, and complicated gut infections, particularly in regions where mixed infections are common.

What are the common side effects of ciprofloxacin-tinidazole combination?

Common side effects of the ciprofloxacin and tinidazole combination include nausea, vomiting, diarrhoea, and stomach discomfort — particularly if taken without food. A metallic or bitter taste in the mouth is very commonly reported with tinidazole. Headache, dizziness, and a dry mouth are also reported. Ciprofloxacin can increase sensitivity to sunlight, so sun protection is important. As with all antibiotics, oral or vaginal thrush (yeast overgrowth) can occur. Most side effects are mild and resolve once the short course is completed.

What side effects of ciprofloxacin-tinidazole need urgent medical attention?

Seek emergency care for signs of a serious allergic reaction (hives, facial swelling, breathing difficulty, or collapse). If you accidentally consume alcohol while on Ciplox TZ and develop severe flushing, vomiting, rapid heartbeat, or feel faint, seek medical help immediately — this is a tinidazole-alcohol reaction. Neurological symptoms — seizures, severe confusion, or numbness and tingling in the hands or feet — need urgent review. Heart rhythm changes (palpitations) or tendon pain (especially in the heel) should be reported to your doctor without delay. Severe watery or bloody diarrhoea requires prompt medical assessment.

Ciplox TZ 500 mg 600 mg