Cyclophil Me 25mg
Available Dosages
| SKU | 286 |
|---|---|
| Generic For | Cyclosporin |
| Strength | 25mg |
| Manufacturer | Biocin Ltd |
| Active Ingredient | Cyclosporine |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 10 Capsules | US$ 1.00 | US$ 10.00 | |||
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| 30 Capsules | US$ 1.00 | US$ 30.00 | |||
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| 60 Capsules | US$ 0.89 | US$ 53.4011%US$ 60.00 | |||
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| 90 Capsules | US$ 0.82 | US$ 73.8018%US$ 90.00 | |||
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Cyclophil Me 25mg (Cyclosporine) – Affordable Cyclosporin Alternative
Cyclophil Me 25 mg is prescribed with other medications to prevent the body from rejecting a transplanted organ (liver, kidney, or heart). It contains the active ingredient Cyclosporine, categorized under the class of medications known as immunosuppressants. It may also be given to treat rheumatoid arthritis and psoriasis.
To prevent organ rejection in transplant patients- It suppresses your body's immune response to help accept newly transplanted organs (kidney, liver, or heart). Cylophil Me may also be prescribed to treat severe rheumatoid arthritis, nephrotic syndrome, and psoriasis.
In rheumatoid arthritis- This is an autoimmune condition, where your body's immune system attacks your body's cells. Cyclosporine stops that from happening and helps relieve the symptoms of this condition, such as swelling, pain, and stiffness in your joints. It also slows down joint damage, reduces disability, and makes you active for as long as possible. It may take up to several weeks or months to notice the effect of the medicine.
Cyclosporine may be prescribed in psoriasis to treat severe psoriasis when other therapies fail to work. In psoriasis patients, skin cells are replaced more quickly than usual. The immunosuppressant medicine can improve your skin and symptoms of redness, rash, and pain.
Precautions of Cyclophil Me 25 mg
Before taking Cyclophil Me 25mg, one should inform your doctor if you have kidney problems, liver issues, gout, high blood pressure, or epilepsy. Also, please inform your doctor about all the medicines you are taking, as they may affect the mechanism of action of Cyclosporine. The immunosuppressant drug should only be used in pregnancy if required. However, it is not recommended while breastfeeding. Cyclosporine should be used with caution in patients with liver and kidney disease. Regular monitoring of kidney function is required.
Side effects of Cyclophil Me 25mg
Common side effects of Cyclophil Me 25mg include diarrhoea, headache, tremors, high blood pressure, and gingival hyperplasia. Because this medicine may interfere with the system's function, you may also catch more infections than usual. Tell your doctor right away if you develop an infection. Because of the same reason, you may have a high risk of developing skin cancer. Limit your exposure to the sun.
How to use Cyclophil Me 25 mg
Take Cyclophil Me 25mg exactly as prescribed by your doctor. Do not take more or less than the prescribed amount. Excessive usage may increase the chance of side effects while using too little can cause you to reject your transplanted organ. Generally, the capsule may be taken before or after consuming food. Stopping the medicine may increase the risk of your transplanted organ being rejected.
What is Cyclophil Me 25mg and what conditions does cyclosporine treat?
Cyclophil Me 25mg contains Cyclosporine 25mg (modified), a calcineurin inhibitor immunosuppressant. It is used to prevent organ transplant rejection, treat severe rheumatoid arthritis, recalcitrant psoriasis, and idiopathic nephrotic syndrome. The 25mg capsule is the smallest strength in the Cyclophil Me range and is particularly useful for precise dose titration in paediatric patients, dose reduction during toxicity management, or as part of complex transplant dosing regimens. It is the generic equivalent of Neoral 25mg soft-gel capsule.
Why is Cyclophil Me 25mg used instead of higher-dose cyclosporine capsules?
Cyclophil Me 25mg is used when small dose increments or reductions are required — such as during initial transplant dose titration, management of mild nephrotoxicity or hypertension, dose adjustment in paediatric patients, or maintenance therapy where lower total daily cyclosporine is appropriate. It allows greater dose flexibility than using only 50mg or 100mg capsules. Because cyclosporine has a narrow therapeutic index, fine dose adjustments based on blood level monitoring are essential, and the 25mg strength enables precise individualised dosing.
Is Cyclophil Me 25mg the same as Neoral 25mg?
Yes. Cyclophil Me 25mg is the generic equivalent of Neoral 25mg, both containing Cyclosporine (modified) 25mg in a microemulsion formulation. Both provide the same pharmacokinetic profile and therapeutic efficacy. The modified microemulsion formulation ensures more consistent absorption than older Sandimmune formulations. Cyclophil Me 25mg is significantly more cost-effective than Neoral. Any switch between cyclosporine formulations must be made under physician supervision with blood level monitoring, as interchangeability requires careful oversight.
How is the dose of Cyclophil Me 25mg determined for a transplant patient?
Cyclosporine dosing (including via Cyclophil Me 25mg) for transplant is strictly individualised and based on blood trough level monitoring, organ type, and rejection risk. Typical initial doses range from 4 to 15 mg/kg/day in two divided doses, with gradual reduction over time. The 25mg capsule enables precise dosing increments. Your transplant specialist uses cyclosporine blood level results (C0 trough or C2 levels) to guide dosing adjustments. Never alter your cyclosporine dose independently — even small changes can lead to rejection or toxicity.
What monitoring is required when taking Cyclophil Me 25mg (cyclosporine)?
Regular monitoring is essential for safe cyclosporine use. This includes blood cyclosporine trough levels (before next dose), serum creatinine and kidney function tests, liver function tests, blood pressure measurement, blood glucose, and lipid profile. Frequency of monitoring is highest in the early post-transplant period and reduces over time as stable levels are established. Skin surveillance for malignancy (especially squamous cell carcinoma) is important for long-term users. Your transplant or specialist team will set your individual monitoring schedule.
Is Cyclophil Me 25mg (cyclosporine) safe during pregnancy?
Cyclosporine (Cyclophil Me) is classified as FDA Pregnancy Category C. It crosses the placenta and is associated with premature birth and low birth weight. However, in organ transplant recipients, cyclosporine is considered relatively safer than alternatives and is often continued in pregnancy under close specialist supervision, as uncontrolled rejection poses greater risk. For autoimmune indications, the risk-benefit balance in pregnancy should be carefully discussed with a specialist. Breastfeeding is not recommended during cyclosporine therapy.
What are the side effects of Cyclophil Me 25mg (low-dose cyclosporine)?
Even at lower cyclosporine doses (25mg range), side effects including nephrotoxicity, hypertension, tremor, hypertrichosis, gingival hyperplasia, and headache can occur. The risk increases cumulatively with dose and duration. Kidney function and blood pressure must be monitored regularly. Drug interactions are a major concern at all doses — CYP3A4 inhibitors increase blood levels and toxicity risk, while inducers decrease therapeutic levels. Always inform all healthcare providers of cyclosporine use before starting any new medication.
Cyclosporine (Cyclophil Me) vs mycophenolate mofetil for transplant: What is the difference?
Cyclosporine (Cyclophil Me) and mycophenolate mofetil (MMF/CellCept) are both immunosuppressants used in transplant management but with different mechanisms and roles. Cyclosporine is a calcineurin inhibitor that suppresses T-cell activation; MMF inhibits lymphocyte proliferation via purine synthesis blockade. Modern transplant protocols typically combine both agents (plus a steroid) for synergistic immunosuppression. Cyclosporine is monitored via blood levels; MMF by clinical response. The combination allows lower individual doses of each, reducing cumulative side effects.
Can Cyclophil Me 25mg be used for nephrotic syndrome in children?
Cyclosporine (Cyclophil Me 25mg) is used for steroid-resistant or steroid-dependent idiopathic nephrotic syndrome in children, under paediatric nephrology supervision. The 25mg strength allows precise weight-based dosing in younger children. Regular kidney function monitoring, urinary protein assessment, and blood pressure measurement are essential during therapy. Cyclosporine achieves proteinuria remission in a significant proportion of children with focal segmental glomerulosclerosis (FSGS) and minimal change disease. Treatment duration and dose are individually tailored by the paediatric nephrologist.
How should I store Cyclophil Me 25mg capsules?
Cyclophil Me 25mg (cyclosporine modified capsules) should be stored at room temperature between 15°C and 30°C (59°F and 86°F), away from moisture and direct light. Do not refrigerate unless specifically instructed, as cold can cause the capsule formulation to change. Keep in the original blister or container until use. Once opened, use promptly. Keep out of reach of children. If the capsule appears discoloured, leaking, or abnormal, discard it and contact your pharmacist. Do not use capsules past their expiry date.
Why should I buy Cyclophil Me 25mg from PremiumRxDrugs.com?
PremiumRxDrugs.com provides genuine Cyclophil Me 25mg (cyclosporine modified) from certified pharmaceutical manufacturers at a fraction of Neoral's branded cost. For patients on sustained immunosuppression requiring precise low-dose or titration flexibility, the 25mg strength and affordable pricing are significant advantages. Customers in the USA, UK, and Australia receive discreet packaging, reliable international delivery, and secure payment. Consistent stock and dedicated customer support make PremiumRxDrugs.com a trusted source for quality cyclosporine therapy.
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