Cyclophil Me 100mg

$2.90

Available Dosages

SKU 285
Generic For Cyclosporin
Strength 100 mg
Manufacturer Biocin Ltd
Active Ingredient Cyclosporine
Pack Size Qty Price Per Pill or Unit Price Cart
30 Capsules US$ 2.90 US$ 86.90
60 Capsules US$ 2.90 US$ 173.80
90 Capsules US$ 2.90 US$ 260.70
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Cyclophil Me 100mg (Cyclosporine) – Affordable Cyclosporin Alternative

Cyclophil Me 100mg is a powerful immunosuprersant medication which has been formulated for the prevention of organ transplant. It is also successful in treating patients with rheumatoid arthritis as well as autoimmune diseases of the blood vessels, muscles, skin, eyes, and lungs.  The medication is manufactured as a capsule for oral adminstration. It is suitable for patients who are hepatitis C positive. The drug is safe and effective for long term therapy in inflammatory disease.

What is Cyclophil Me 100mg used for?

It is indicated for:

  • Prevention of organ transplant rejection
  • Treatment of rheumatoid arthritis
  • Treatment of autoimmune disorders

How does Cyclophil Me 100mg work?

Cyclophil me 100mg contains the active component Cyclosporine works by inhibiting immune response, which in turn inhibits a factor important for initiation of T-cell activity. In this way it prevents rejection reactions and also slowed progression of rheumatoid arthritis or psoriasis.

Effects of grape juice on Cyclophil Me 100mg

Concurrent ingestion of grapefruit or grapefruit juice may increase serum levels and should be avoided during the treatment of Cyclophil Me.

What medications interact with Cyclophil Me 100mg?

Inform your physicians about the following medications:

  • Amiodarone
  • Clarithromycin
  • Colchicines
  • Fluoroquinolones
  • Danazal
  • Erythromycin
  • Allopurinol
  • Azithromycin
  • Metochlopramide
  • Nicardipine
  • Imatinib
  • Diltiazem
  • Fluoconazole
  • Digoxin
  • Bromocriptine
  • Nefazodone
  • Telaprevir
  • Hormonal contraceptives
  • Cyclophosphamide
  • Azathioprine
  • Verapamil
  • Boceprevir
  • Dalfopristin
  • Methylprednisolone
  • Phenobarbital
  • Bosentan
  • Corticosteroids
  • Rifampin
  • Ticlopidine
  • Rifampin
  • Octreotide
  • Nafcillin
  • Carbamazepine
  • Orlistat
  • Potassium sparing diuretics
  • ACE inhibitors
  • Potassium supplements
  • Repaglinide
  • Sirolimus
  • Nifedipine
  • HMG-coa reductase inhibitors
  • Ambrisentan
  • Etoposide
  • Aliskeran
  • Colchicines
  • Nsaids
  • Ranitidine
  • Ketoconazole
  • Vacomycin
  • Melphalan
  • Amphoterecin B
  • Ciprofloxacin
  • Sulfamethoxazole
  • Fibric acid derivative
  • Aminoglycosides

When should Cyclophil Me not be taken?

The use of Cyclophil Me is contraindicated in the following conditions:

  • Uncontrolled hypertension
  • Uncontrolled infection
  • Hypersensitivity to Cyclosporine
  • Abnormal kidney function
  • Gout
  • Primary or secondary immunodeficiency excluding autoimmune disease
  • Abnormal liver function
  • Malignancy within the last five years

The medicine should be used with caution in the following patients:

  • Undergoing radiation therapy
  • With controlled hypertension
  • Obese patients
  • Who are pregnant or contemplating pregnancy
  • With a background infection
  • Geriatrics who are at greater risk for renal insufficiency or hypertension

What are the side effects of Cyclophil Me 100mg?

  • Gastrointestinal issues- diarrhea, vomiting, anorexia, pancreatitis, abdominal discomfort, hepatotoxicity
  • Central nervous system- seizures, tremor, flushing, psychiatric problems, posterior reversible encephalopathy syndrome, confusion, leukoencephalopathy
  • Genitouterine disorders- nephrotoxicity
  • Metabolic disorders- hyperurecemia, hyperlipidemia
  • Cardiovascular system disorders- hypertension
  • Neurological issues- paresthesia, hyperparesthesia
  • F and E disorder- hypomagnesemia, hyperkalemia
  • Hematological problems- leukopenia, anemia, thrombocytopenia
  • Dermatological issues- psoriasis, acne, hirsutism
  • Miscellaneous issues- hypersensitivity reactions, infections, gingival hyperplasia, malignancy

How should Cyclophil Me 100mg be taken?

  • For severe psoriasis- 2.5 mg/kg/day given in two divided doses, for at least two weeks. The dose may increase by 0.5 mg/kg/day for two weeks, up to 4 mg/kg/day. In case adverse reactions reported, the dose may decrease by 25-50%.
  • For autoimmune disorders- the recommended dose is 1 to 3 mg per kg daily.
  • For prevention of transplant rejection, patients should be assessed for symptoms of organ rejection.
  • For arthritis, patients should be assessed pain and limitations of movement before and after during administration.
  • The medication must be taken exactly as directed by your health care specialist. Never increase, decrease, or stop taking it without first checking with your health care professional. Do not break or chew the capsule. You must take the capsule just after eating a meal to avoid gastrointestinal disorders.
  • The health care specialist will check blood tests on a regular basis to monitor for significant changes.

How long should you take Cyclophil Me 100mg?

The medicine should be taken for as long as recommended by your health care specialist.

Missed dose of Cyclophil Me 100

If you forget or miss a dose of Cyclophil Me 100mg, do not try to make it up by taking an extra dose. Instead, go back to your normal dosing schedule as soon as you can and inform your health care specialist about the dose that you have missed.

How should Cyclophil Me 100mg be stored?

  • The medicine should be stored in the original package at controlled temperature
  • Store it in a place where children and pets cannot reach
  • Place it away from moisture, heat, and direct light
Cyclophil Me 100mg

What is Cyclophil Me 100mg and what is cyclosporine used for?

Cyclophil Me 100mg contains Cyclosporine 100mg (modified), a potent calcineurin inhibitor (immunosuppressant) used for organ transplant rejection prevention, rheumatoid arthritis, severe psoriasis, and nephrotic syndrome. It works by inhibiting T-lymphocyte activation, suppressing the immune response that would otherwise attack transplanted organs or drive autoimmune conditions. Cyclophil Me is the generic equivalent of Neoral 100mg soft-gel capsule. The 100mg strength is typically used for transplant maintenance dosing or serious autoimmune conditions requiring higher immunosuppression.

How long does Cyclophil Me 100mg (cyclosporine) take to work for autoimmune conditions?

For autoimmune conditions like rheumatoid arthritis or psoriasis, measurable improvement with Cyclophil Me 100mg (cyclosporine) typically begins within 4 to 8 weeks of achieving therapeutic blood levels. Full clinical benefit — significant joint inflammation reduction or skin clearance — may take 3 to 6 months. For organ transplant rejection prevention, cyclosporine begins working immediately with appropriate blood level establishment. Blood cyclosporine levels are monitored regularly to ensure therapeutic concentrations are maintained throughout treatment.

Is Cyclophil Me 100mg the same as Neoral 100mg?

Yes. Cyclophil Me 100mg is the generic equivalent of Neoral 100mg, both containing Cyclosporine (modified) 100mg as a microemulsion formulation. The microemulsion (modified) formulation of both products provides more consistent absorption than the original Sandimmune formulation. Both produce the same pharmacokinetic profile and therapeutic outcomes. Cyclophil Me is significantly more affordable than Neoral. However, due to the narrow therapeutic index of cyclosporine, any change between formulations must be made under physician supervision with blood level monitoring.

What is the correct dosage of Cyclophil Me 100mg for organ transplant patients?

Cyclosporine (Cyclophil Me) dosing for transplant is highly individualised. In kidney, liver, or heart transplant patients, total daily doses typically range from 2 to 15 mg/kg/day in two divided doses, gradually reduced to maintenance levels based on blood cyclosporine levels (trough monitoring). The 100mg capsule is useful for patients requiring higher single-dose components. Your transplant specialist will determine and adjust your specific dose based on drug blood levels, organ function, and rejection risk. Never self-adjust cyclosporine dosing.

What are the serious side effects of Cyclophil Me 100mg (cyclosporine)?

Cyclosporine (Cyclophil Me) carries significant side effect risks including nephrotoxicity (kidney damage), hypertension, hypertrichosis (excessive hair growth), gingival hyperplasia (gum overgrowth), tremor, headache, and elevated liver enzymes. Long-term use increases the risk of infection, malignancies (particularly skin cancers and lymphomas), and metabolic disturbances. Regular monitoring of kidney function, blood pressure, blood counts, and cyclosporine trough levels is mandatory. Report any signs of kidney problems, severe infection, or unusual skin lesions to your specialist immediately.

Is Cyclophil Me 100mg (cyclosporine) safe to take long-term?

Cyclophil Me 100mg can be used long-term under close specialist supervision in transplant and autoimmune patients, but it requires rigorous ongoing monitoring due to cumulative nephrotoxicity and other risks. Regular blood cyclosporine level testing, kidney function tests, blood pressure checks, and skin surveillance for malignancy are essential with long-term use. For autoimmune indications, cyclosporine is often used for defined treatment courses (typically up to 1 year) rather than indefinitely, to minimise cumulative toxicity risk.

What drug interactions does Cyclophil Me 100mg (cyclosporine) have?

Cyclosporine has extensive, clinically significant drug interactions. CYP3A4 inhibitors (ketoconazole, clarithromycin, verapamil, grapefruit juice) increase cyclosporine blood levels and toxicity risk. CYP3A4 inducers (rifampicin, phenytoin, carbamazepine, St John's Wort) decrease levels and risk rejection. Combining cyclosporine with nephrotoxic drugs (NSAIDs, aminoglycosides, amphotericin B) increases kidney damage risk. Statins taken with cyclosporine carry myopathy risk. Always inform all treating doctors and pharmacists of cyclosporine use before any new medication is started.

Cyclophil Me (cyclosporine) vs tacrolimus for organ transplant: Which is better?

Both cyclosporine (Cyclophil Me) and tacrolimus are calcineurin inhibitors for transplant immunosuppression, but tacrolimus is generally preferred as the primary agent in modern transplant protocols due to superior rejection rates and lower acute rejection incidence. Cyclosporine has a longer clinical track record and may have some advantages in specific patient populations. Both require blood level monitoring and carry nephrotoxicity risk. Tacrolimus is associated with higher rates of post-transplant diabetes; cyclosporine with hypertension and gingival overgrowth. Your transplant team will determine the optimal agent.

Does Cyclophil Me 100mg need to be taken with food?

Cyclophil Me 100mg (cyclosporine modified capsules, equivalent to Neoral) should be taken consistently with respect to meals — either always with food or always without, at the same time each day. The microemulsion formulation has more consistent absorption than earlier formulations, but meal content (particularly high-fat meals) can still affect drug levels. Avoid grapefruit and grapefruit juice entirely, as they significantly increase cyclosporine blood levels. Maintain strict consistency in dosing time and food intake to keep blood levels stable.

Can Cyclophil Me 100mg be used for severe psoriasis treatment?

Yes. Cyclosporine (Cyclophil Me 100mg) is an established treatment for severe, recalcitrant plaque psoriasis that has not responded adequately to topical treatments or phototherapy. It produces rapid, effective clearance of psoriatic plaques through T-cell suppression. For psoriasis, cyclosporine is typically used for short courses of 3 to 6 months at the lowest effective dose to minimise cumulative toxicity. Long-term continuous use is avoided in psoriasis due to nephrotoxicity risk. Dermatologist supervision with regular kidney function and blood pressure monitoring is mandatory.

Why should I buy Cyclophil Me 100mg from PremiumRxDrugs.com?

PremiumRxDrugs.com provides genuine Cyclophil Me 100mg (cyclosporine modified) from certified manufacturers at prices significantly below branded Neoral. For transplant patients and those with autoimmune conditions on sustained cyclosporine therapy, the cost savings are significant. Customers in the USA, UK, and Australia receive discreet packaging, reliable delivery, and secure checkout. Consistent stock, verified product quality, and responsive customer support make PremiumRxDrugs.com a trusted, affordable source for this critical immunosuppressant medication.

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