Cytogard 20mg
Available Dosages
| SKU | 1158 |
|---|---|
| Generic For | Vastarel |
| Strength | 20mg |
| Active Ingredient | Trimetazidine |
Out Of Stock
Cytogard 20mg (Trimetazidine) – Affordable Vastarel Alternative
Cytogard 20 mg (Trimetazidine)
Cytogard 20 mg consists of an active ingredient Trimetazidine . Trimetazidine is described as the first cytoprotective anti-ischemic agent. It inhibits fatty acid oxidation, and Reactive oxidation species production. Trimetazidine limits oxygen consumption, and preserves mitochondrial functioning during hypoxia. It shows anti-ischemic effects, and vasodilatory effects in vivo.
What is Cytogard 20 mg used for?
Cytogard 20 mg is prescribed as a long-term treatment of angina pectoris. The medicine increases coronary flow reserve, thereby delaying the onset of ischemia related with exercise, limits rapid swings in blood pressure without any specific variations in the heart rate, significantly decreases the number of angina attacks, and leads to significant decrease in the use of nitrates. Trimetazidine also improves the left ventricular function in diabetic patients with CHD. Buy Cytogard 20 mg online to treat conditions that are mentioned above.
How does Cytogard work?
Cytogard is a metabolic drug that improves glucose oxidation, and maintains energy metabolism during ischemia. It stops the β oxidation of fatty acids to enhance the glucose oxidation. The glucose oxidation optimises cellular energy processes, and maintains energy metabolism in ischemia or hypoxia. The medicine maintains the cellular homeostasis by increasing the cell tolerance to hypoxia or ischemia. In this way, Trimetazidine decreases the frequency of angina attacks, and gives symptomatic relief to angina pain.
What are the different doses of Cytogard?
Cytogard is available to order online from premiumrxdrugs.com. You can buy Cytogard 20 mg online at unbeatable price.
How should Cytogard be taken?
- Cytogard is present in the sustained release tablet form. It should be taken twice daily, or as your physician suggests. Swallow the medicine with an adequate amount of water.
- Take the tablet exactly as prescribed by the doctor. Do not alter the dosage plan.
- The dose regimen varies from patient to patient; it depends on the condition of the patients.
- Take Cytogard tablets strictly according to your doctor’s instruction. Do not alter the dosage plan unless your physician advises you to do so.
- Take the medicine regularly to get the best results.
- To help you remember, take the tablets at the same time, each day.
- In some cases, the condition may become worse when the intake of the medicine is stopped suddenly. Your dose may need to be slowly decreased.
- Overdose: Seek medical attention immediately, in the case of an overdose of Trimetazidine.
- Take the tablets for as long as your physician recommends.
Missed dose of Cytogard:
If you have forgotten a dose, take it as soon you remember and go back to your usual dosing schedule. If the time to take the next dose is near, leave the forgotten dose and take the next dose. Do not double the dose to compensate the forgotten one.
What are Side effects of Cytogard?
Like other medicines, Cytogard may cause adverse effects. Seek medical attention, in case the given troubles arise:
- Headache
- Dizziness
- Blurred vision
- Lightheadedness
Some serious and rare adverse effects that need serious consideration are listed below:
- Diarrhea
- Sickness
- Palpitations
- Constipation
- High level of uric acid in the blood
- Muscle cramps
What medications interact with Cytogard?
Avoid consuming Cytogard, if you are taking the medicines that are given below:
- Ketoconazole
- Erythromycin
- Ketoconazole
- Trazodone
- Fluconazole
- Sotalol
- Barbiturates
- Pimozide
- Telithromycin
- Itraconazole
- Trazodone
- Fluconazole
- Phenytoin
- Rifampicin
- Verapamil
- Ritonavir
- Mirtazapine
- Nefazodone
- Nelfinavir
- Bupropion
- Diltiazem
- Mirtazapine
- Josamycin
When should Cytogard not be used?
Avoid taking Cytogard in the following conditions:
- If you are hypersensitive to the drug, or its components.
- If you are a woman of childbearing potential
- Breastfeeding women are advised not to take Trimetazidine as it may pass into the breast milk and harm the nursing baby.
Talk to your doctor, before taking Cytogard if:
- If you have allergies to food, medicines, and other substances.
- If you are suffering from kidney disorders.
- If you are suffering from tremors.
- If you are suffering from hypotension.
- If you have a history of a stroke, or a heart attack.
- If you are suffering from Parkinson’s syndrome.
- If you are an elderly person.
- If you have undergone pacemaker implantation.
- If you are consuming any prescription or non prescription medicines.
- If you are hypersensitive to some food products.
How should Cytogard be stored?
- The drug may cause dizziness. Do not drive or use machinery, while taking Cytogard, as these activities may require a high degree of mental attention.
- Do not forget to see the expiry date of the product.
- Store the tablets in a dry place and out of the direct light.
- It should be stored at a room temperature.
- Place the medicine away from infants.
What is Cytogard 20mg used for?
Cytogard 20mg contains trimetazidine 20mg — a metabolic anti-anginal agent that works differently from nitrates, beta-blockers, and calcium channel blockers. Rather than reducing heart rate or vaSodiumilating coronary arteries, it protects cardiac muscle cells at the metabolic level during ischaemia, improving myocardial energy efficiency. It is used for the prophylaxis of stable angina pectoris, typically as add-on therapy to other anti-anginal medications. Trimetazidine is approved in many countries (excluding the USA) for stable angina.
How does trimetazidine protect the heart from ischaemia?
Trimetazidine inhibits 3-ketoacyl coenzyme A thiolase (3-KAT), the last enzyme in beta-oxidation of fatty acids. During cardiac ischaemia, the heart normally shifts from glucose to fatty acid metabolism, which is less oxygen-efficient and generates more acidosis. Trimetazidine blocks this metabolic shift, forcing the ischaemic heart to continue using glucose — which requires less oxygen per ATP molecule produced. This metabolic optimisation reduces ischaemic cellular damage without haemodynamic effects, allowing the heart to function more efficiently during periods of reduced blood flow.
How should Cytogard 20mg be taken?
Cytogard 20mg (standard-release trimetazidine) is taken three times daily — morning, midday, and evening — ideally with meals to reduce GI side effects. Each dose maintains metabolic cardiac protection throughout the day. Consistent dosing without skipping is important for ongoing anti-ischaemic benefit. Renal dose reduction is required in moderate CKD (eGFR 30–60 ml/min — reduce to 20mg twice daily); trimetazidine is contraindicated in severe renal failure (eGFR <30 ml/min) due to accumulation.
How long does Cytogard 20mg take to reduce angina frequency?
Trimetazidine works through cellular metabolic adaptation rather than immediate haemodynamic changes. Reduction in angina attack frequency and improvements in exercise tolerance typically become apparent after 2–4 weeks of consistent therapy. Maximum benefit is assessed at 8–12 weeks. Clinical trials demonstrate that adding trimetazidine to conventional anti-anginal therapy reduces weekly angina attacks and nitroglycerin consumption, and improves exercise duration on stress testing, without changes in resting heart rate or blood pressure.
Is Cytogard 20mg safe long-term?
Trimetazidine has been used for decades in stable angina with a generally good long-term safety record. The main safety concern identified in 2012 was movement disorders — Parkinson-like symptoms, tremor, and gait instability — particularly in elderly patients and those with CKD. The European Medicines Agency (EMA) reviewed and restricted its use: it should not be used in patients with Parkinson's disease, parkinsonian symptoms, tremor, or restless legs syndrome. Symptoms resolve on discontinuation in most patients.
Who should not use Cytogard 20mg?
Trimetazidine is contraindicated in: Parkinson's disease or symptoms (tremor, muscle rigidity, gait problems), restless legs syndrome, severe renal impairment (eGFR <30 ml/min), and known hypersensitivity to trimetazidine. It is not approved or available in the USA. Use with caution in moderate CKD (dose reduction required). Elderly patients are at higher risk of movement side effects. It is not a substitute for evidence-based therapies (beta-blockers, ACE inhibitors, statins, aspirin) in ischaemic heart disease.
How does Cytogard 20mg compare to Flavedon MR 35mg?
Both contain trimetazidine but differ in dose and release: Cytogard 20mg is standard-release taken three times daily; Flavedon MR 35mg is modified-release taken twice daily. The MR formulation provides more sustained plasma levels with simpler twice-daily dosing, which may improve adherence. Both provide equivalent metabolic anti-anginal benefit. The MR formulation is preferred in many guidelines for the convenience of twice-daily dosing, while standard-release 20mg TID is an appropriate alternative where the MR formulation is not available.
Is Cytogard 20mg the same as Vastarel 20mg?
Yes. Cytogard 20mg and Vastarel 20mg both contain trimetazidine 20mg in standard-release form. Both are bioequivalent with identical metabolic anti-ischaemic mechanisms. Cytogard is the generic formulation available in various markets, providing the same anti-anginal metabolic protection as Vastarel at a more affordable price.
Where can I buy Cytogard 20mg online?
Cytogard 20mg is available at PremiumRxDrugs.com, which ships to the USA, UK, Australia, and worldwide. Our licensed pharmacy provides authentic manufacturer-sourced trimetazidine at competitive prices. Free shipping on qualifying orders, discreet delivery, and easy prescription management make this metabolic anti-anginal therapy accessible internationally.
Can I order Cytogard 20mg from PremiumRxDrugs for international delivery?
Yes. PremiumRxDrugs.com ships Cytogard 20mg to the USA, UK, Australia, and many countries worldwide. Our genuine manufacturer-verified cardiovascular medications, transparent pricing, and free worldwide shipping on qualifying orders make us a reliable international pharmacy for patients requiring trimetazidine therapy for stable angina.
What side effects does Cytogard 20mg cause?
GI side effects (nausea, vomiting, abdominal discomfort) are the most common, generally mild and reduced by taking with meals. Dizziness and headache are occasionally reported. The most clinically significant side effects are movement disorders: Parkinson-like symptoms (rigidity, tremor, bradykinesia), gait instability, and restless legs syndrome — these occur more frequently in elderly patients and those with CKD. These movement effects are reversible on stopping trimetazidine. Report any tremor or walking difficulties to your doctor immediately.
What precautions apply to Cytogard 20mg users?
Assess movement and gait at baseline before starting trimetazidine. Monitor for tremor, muscle stiffness, or balance problems at each follow-up. Stop immediately and seek medical attention if movement disorders develop. Do not use in patients with any pre-existing movement disorders. Reduce dose in moderate CKD. Discontinue if symptoms of restless legs syndrome develop. Do not rely on trimetazidine as the sole anti-anginal medication — it is an add-on to, not a replacement for, evidence-based therapies including beta-blockers, nitrates, and calcium channel blockers.
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