Diane 35mg
Available Dosages
| SKU | 291 |
|---|---|
| Generic For | Diane |
| Strength | 35mg |
| Active Ingredient | Cyproterone Acetate+ Ethyl Estradiol |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 21 Tablet/s | US$ 0.57 | US$ 12.01 | |||
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| 42 Tablet/s | US$ 0.57 | US$ 24.02 | |||
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| 84 Tablet/s | US$ 0.57 | US$ 48.05 | |||
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Diane 35mg (Cyproterone Acetate+ Ethyl Estradiol)
Diane 35 mg tablets contain two active therapeutic ingredients cyproterone acetate ethylestradiol. It is used to treat women with severe signs of androgenisation (over-production of androgen), that can produce conditions like unwanted hair (hirsutism) and hair loss (androgenic alopecia) both caused by excess androgen production. These conditions are often accompanied by acne, inflammation and greasy skin from too much sebum (seborrhoea). Diane 35mg tablets decrease the symptoms of androgen-dependent conditions where oral antibiotic or local treatment alone has not been successful. It can also be used for oral contraception at the same time as they are being used to treat androgen-dependent conditions, however, \this medication should not be used for contraception alone. Diane 35 mg tablets can be used for the treatment of polycystic ovary syndrome, which is also caused by excess amount of androgen and is usually accompanied by acne and hirsutism.
What is Diane 35 used for?
The tablets have several uses:
- Severe acne in women that has not responded to treatment with oral antibiotics.
- Unusual hair growth in women body as a outcome of excessive production of male sex hormones (hirsutism).
- This medicine will also provide contracertion for women taking it for acne or hirsutism, but it should not be used solely as a contraceptive.
How does Diane works?
Diane 35 mg tablets contains two active ingredient first is ethinyloestradiol, a synthetic estrogen, and cyproterone acetate, which is a derivative of progestagen and is also an anti-androgen. These two hormones work together to undo the effects of too much androgen, while at the same point in time protecting against pregnancy. Although androgens, one of which is testosterone, are considered mainly as male hormones, women also produce androgens, although in much lesser amounts. Androgens have several functions in the female body, including puberty related changes like pubic hair development, preventing bone loss, libido and for the production of estrogen. However, some women produce a lot of androgen and this can cause hirsutism (unwanted hair) and other unwanted symptoms of androgen overproduction like acne and/or seborrhoea (greasy skin from too much sebum) and androgen-dependent alopecia (hair loss). Cyproterone in Diane 35 mg tablets blocks the production of androgens by the ovaries and binds to the androgen receptors on specific cells in the pilosebaceous unit in the skin (contains sebum-producing sebaceous glands and hair follicles), blocking the androgen-dependent over stimulation of sebum and over development of hair in body. The ethinyloestradiol component enhances the effect of cyproterone by reducing the amount of androgens in the circulation, relieving symptoms like acne and hirsutism. The combination of a cyproterone and ethinyloestradiol provides effective contraception, by blocking ovulation, preventing growth of the endometrium so that a fertilised egg would not be able to implant and grow, and preventing the thinning of cervical secretions so that sperm cannot get through.
What medications interact with Diane 35?
It is important to tell your health care specialist what medicines you are already taking including those bought with prescription or without a prescription and herbal medicines, before you begin taking this medicine. Similarly, check with your health care specialist before taking any new medicines while using this one, to make sure that the combination drug is safe for your health.
When should Diane not be used?
You should not take Diane 35 mg if you:
- are allergic to ethinyloestradiol or cyproterone or any of the ingredients in Diane 35 tablets
- are pregnant or planning to become pregnant
- are taking another form of oral contraception
- have a past or family history of endometrial carcinoma or liver disease, carcinoma of the breast
- have high blood pressure, migrane
- have had deep venous thrombosis, heart attack or stroke
- have diabetes with changes to the blood vessels
- are taking other medications that may interact with Diane 35, such as anticonvulsants like carbamazepin and phenytoin, barbiturates, anti-infectives like rifabutin, nevirapine, rifampicin, the antifungal griseofulvin, antibiotics like penicillin, preparations containing St John's Wort
What are the side effects of Diane?
The most frequently reported side effects when taking Diane – 35 mg tablets are:
- Headache
- Breast pain
- Breast tenderness
- Nausea
- Skin rash and itching
- Abdominal pain
- Insomnia and depression.
Less common side effects include:
- Changes in body weight
- Changes in libido.
- Migraine
- Fluid retention
How should Diane 35mg be used?
You should take your Diane 35 swallowed whole with a glass of water once daily at the same time each day and follow the instructions provided. For information about administration of medicines please consult your health care specialist.
How long you should use Diane?
You should take Diane 35 mg continually to ensure effective contraception and for as long as your health care specialist recommends. You should expect your acne to clear up entirely within a few months, but in particularly severe cases treatment for longer may be necessary before the full benefit is seen. You may be advised to keep taking your Diane 35 mg tablets for a few more months after the acne has disappeared and you should then change to another oral contraceptive.
Missed dose of Diane
In case if you miss a dose, consume a dose as soon as you notice. If you are close to the time for your next dose, wait until then and then consume your medicine. Never consume extra medicine to make up for a dosage that you have missed. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your health care specialist to discuss changes in schedule or a new schedule to make up for missed medicines, if you have missed too many doses in the recent pastime.
How should Diane 35mg be stored?
- Store at 25 C
- Keep Diane tablets in their calendar pack until use
- Keep medicines away from the sight of children’s and pets
- Away from sun – light, heat, and moisture
What is Cyproterone Acetate and Ethyl Estradiol and what condition does it treat?
Cyproterone Acetate combined with Ethyl Estradiol is a hormonal medication commonly sold under the brand name Diane 35mg. This combination therapy is primarily prescribed to treat moderate to severe acne in women, particularly when related to hormonal imbalances or androgen sensitivity. The medication also addresses symptoms of androgenization such as excessive facial or body hair growth. Additionally, this oral contraceptive pill provides effective birth control protection. The anti-androgen properties of cyproterone acetate work alongside the estrogen component to regulate hormone levels, making it particularly effective for hormonally-driven skin conditions in women of reproductive age.
How does Cyproterone Acetate and Ethyl Estradiol work in the body?
Diane 35mg works through a dual-action mechanism combining anti-androgen and hormonal effects. Cyproterone Acetate blocks androgen receptors, preventing male hormones like testosterone from binding to skin cells and sebaceous glands. This reduces oil production and inflammation that trigger acne breakouts. Meanwhile, Ethyl Estradiol, a synthetic estrogen, suppresses the natural production of androgens by the ovaries while regulating the menstrual cycle. Together, these active ingredients rebalance hormone levels, diminish sebum secretion, and prevent ovulation. The combined hormonal contraceptive also thickens cervical mucus, providing reliable birth control alongside dermatological benefits for hormonally-influenced skin conditions.
How long does Diane 35mg take to work for acne and hormonal symptoms?
Diane 35mg typically requires patience, as hormonal acne treatments work gradually. Most women notice initial improvements in skin condition within six to eight weeks of starting treatment, though visible acne reduction may take three to four months. Maximum therapeutic benefits for moderate to severe acne usually appear after six months of consistent use. The contraceptive effect begins immediately if started on the first day of menstruation, or after seven days if started mid-cycle. Symptoms like excess hair growth respond more slowly, often requiring six to twelve months. Individual response times vary based on acne severity and hormonal balance, so continued use as prescribed yields the best outcomes.
When and how should I take Diane 35mg for best results?
Take one Diane 35mg tablet daily at the same time each day for 21 consecutive days, followed by a seven-day break during which withdrawal bleeding occurs. Start your next blister pack after the pill-free week, even if bleeding continues. Swallow the tablet whole with water, with or without food. Begin the first pack on day one of your menstrual period for immediate contraceptive protection. Taking tablets at a consistent time improves effectiveness and helps establish routine. Missing doses reduces both acne control and contraceptive reliability. Always consult your healthcare provider regarding your specific treatment schedule and discuss any medications you currently take to avoid potential interactions.
Is Diane 35mg safe for long-term use or should it be limited?
Diane 35mg is typically prescribed for treating acne rather than long-term contraception alone. Medical guidelines generally recommend discontinuing this anti-androgen hormonal therapy three to four cycles after acne clears completely. Prolonged use beyond what's medically necessary may increase risks associated with combined hormonal contraceptives, including blood clots, particularly in women with additional risk factors like smoking or obesity. Your doctor will regularly assess whether continued treatment remains appropriate based on symptom improvement and your individual health profile. Some women may use it longer under medical supervision if acne returns after discontinuation or if benefits outweigh potential risks in their specific situation.
Can I take Diane 35mg with other medicines or supplements?
Certain medications can interact with Diane 35mg, potentially reducing its effectiveness or increasing side effects. Antibiotics like rifampicin, some antifungals, anticonvulsants, and HIV medications may decrease the contraceptive and therapeutic efficacy of this hormonal treatment. St John's Wort, a herbal supplement, significantly reduces hormone levels in the blood. Conversely, Diane 35mg may affect how other medicines work, including some diabetes medications and immunosuppressants. Grapefruit juice can increase estrogen levels. Always inform healthcare providers and pharmacists about all prescription drugs, over-the-counter medicines, vitamins, and herbal supplements you're taking before starting cyproterone acetate with ethyl estradiol to ensure safe concurrent use.
How does Diane 35mg compare to other acne treatments and birth control pills?
Diane 35mg stands apart from standard birth control pills due to its anti-androgen component, making it specifically effective for hormonal acne and androgenization symptoms. Regular contraceptive pills lack cyproterone acetate's androgen-blocking properties. Compared to topical acne treatments or antibiotics, this systemic hormonal therapy addresses root hormonal causes rather than surface symptoms, making it more effective for persistent hormonally-driven breakouts. Unlike spironolactone, another anti-androgen medication, Diane 35mg provides simultaneous contraception. However, it carries slightly higher thrombosis risks than some modern low-dose contraceptives, so doctors prescribe it specifically when anti-androgen effects are therapeutically necessary rather than for contraception alone.
Is generic Cyproterone Acetate plus Ethyl Estradiol as effective as branded Diane 35mg?
Generic versions containing cyproterone acetate and ethyl estradiol are therapeutically equivalent to branded Diane 35mg, delivering the same active ingredients in identical strengths. Regulatory authorities in the USA, UK, Australia, and Canada require generic hormonal medications to demonstrate bioequivalence, meaning they work in your body the same way as branded versions. The anti-androgen and contraceptive effects remain equally effective whether you choose generic or branded formulations. Generic options typically cost significantly less while maintaining the same quality standards and clinical outcomes. The main differences lie in inactive ingredients, packaging, and price rather than therapeutic performance, making generics a cost-effective choice for acne treatment and birth control.
Why do patients choose PremiumRxDrugs for Diane 35mg prescriptions?
Patients trust PremiumRxDrugs for Diane 35mg supply because of transparent,competitive pricing that makes ongoing hormonal acne treatment more affordable. The pharmacy stocks only genuine manufacturer-sourced medications, eliminating concerns about counterfeit pills common with unlicensed sellers. Convenient features include straightforward prescription management, easy reordering systems, and discreet packaging that protects privacy. With reliable worldwide shipping covering the USA, UK, Australia, Canada, and beyond, plus free shipping options, patients receive their contraceptive and anti-androgen medication consistently without pharmacy trips. Over ten years of trusted service demonstrates commitment to customer care. This combination of authenticity assurance, affordability, convenience, and established reputation makes PremiumRxDrugs a preferred choice for women managing hormonal acne.
What are the common side effects of Cyproterone Acetate and Ethyl Estradiol?
Common side effects when taking cyproterone acetate combined with ethyl estradiol include nausea, headaches, breast tenderness, mood changes, and weight fluctuation. Some women experience breakthrough bleeding or spotting between periods, particularly during initial treatment months. Decreased libido occasionally occurs due to the anti-androgen effect. Mild fluid retention and bloating are reported. Most side effects diminish as your body adjusts to the hormonal medication over two to three cycles. Serious but rare risks include blood clots, particularly in smokers or those with clotting disorders. Contact your healthcare provider if you experience severe headaches, vision changes, chest pain, leg swelling, or persistent abdominal pain, as these may indicate complications requiring immediate medical attention.
Who should avoid taking Cyproterone Acetate and Ethyl Estradiol?
Cyproterone acetate with ethyl estradiol is contraindicated for women with history of blood clots, stroke, heart disease, or conditions increasing thrombosis risk. Avoid this hormonal treatment if you have liver disease, liver tumors, or unexplained vaginal bleeding. Women with breast cancer or other hormone-sensitive cancers should not use this anti-androgen contraceptive. Smokers over 35 face significantly elevated stroke and clot risks. Those with severe diabetes complications, migraines with aura, or uncontrolled high blood pressure should choose alternative acne treatments. Pregnant or breastfeeding women cannot take this medication. Men should not use this formulation due to feminizing effects. Always disclose your complete medical history to ensure this combined hormonal therapy is appropriate for your individual health circumstances.
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