Cyproterone Acetate Ethyl Estradiol
|Generic Name||Cyproterone Acetate+ Ethyl Estradiol|
Diane 35 mg ( Cyproterone Acetate Ethyl Estradiol)
Diane tablets contain two active therapeutic ingredients cyproterone acetate ethylestradiol. It is used to treat women with severe signs of androgenisation (over-production of androgen), that can produce conditions like unwanted hair (hirsutism) and hair loss (androgenic alopecia) both caused by excess androgen production. These conditions are often accompanied by acne, inflammation and greasy skin from too much sebum (seborrhoea). Diane 35mg tablets decrease the symptoms of androgen-dependent conditions where oral antibiotic or local treatment alone has not been successful. It can also be used for oral contraception at the same time as they are being used to treat androgen-dependent conditions, however, \this medication should not be used for contraception alone. Diane 35 mg tablets can be used for the treatment of polycystic ovary syndrome, which is also caused by excess amount of androgen and is usually accompanied by acne and hirsutism.
Diane general information
What is Diane used for?
The tablets have several uses:
- Severe acne in women that has not responded to treatment with oral antibiotics.
- Unusual hair growth in women body as a outcome of excessive production of male sex hormones (hirsutism).
- This medicine will also provide contracertion for women taking it for acne or hirsutism, but it should not be used solely as a contraceptive.
How does Diane works?
Diane – 35mg tablets contains two active ingredient first is ethinyloestradiol, a synthetic estrogen, and cyproterone acetate, which is a derivative of progestagen and is also an anti-androgen. These two hormones work together to undo the effects of too much androgen, while at the same point in time protecting against pregnancy. Although androgens, one of which is testosterone, are considered mainly as male hormones, women also produce androgens, although in much lesser amounts. Androgens have several functions in the female body, including puberty related changes like pubic hair development, preventing bone loss, libido and for the production of estrogen. However, some women produce a lot of androgen and this can cause hirsutism (unwanted hair) and other unwanted symptoms of androgen overproduction like acne and/or seborrhoea (greasy skin from too much sebum) and androgen-dependent alopecia (hair loss). Cyproterone in Diane 35 mg tablets blocks the production of androgens by the ovaries and binds to the androgen receptors on specific cells in the pilosebaceous unit in the skin (contains sebum-producing sebaceous glands and hair follicles), blocking the androgen-dependent over stimulation of sebum and over development of hair in body. The ethinyloestradiol component enhances the effect of cyproterone by reducing the amount of androgens in the circulation, relieving symptoms like acne and hirsutism. The combination of a cyproterone and ethinyloestradiol provides effective contraception, by blocking ovulation, preventing growth of the endometrium so that a fertilised egg would not be able to implant and grow, and preventing the thinning of cervical secretions so that sperm cannot get through.
Where to buy Diane online?
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What does Diane contains?
Diane 35 contain active ingredients consisting of a combination of ethinyloestradiol, a synthetic oestrogen, and cyproterone acetate, which is a progestagen and also an anti-androgen, that work together to undo the effects of too much androgen, while at the same point in time protecting against pregnancy.
What are the side effects of Diane?
The most frequently reported side effects when taking Diane – 35 mg tablets are:
- Breast pain
- Breast tenderness
- Skin rash and itching
- Abdominal pain
- Insomnia and depression.
Less common side effects include:
- Changes in body weight
- Changes in libido.
- Fluid retention
What medications interact with Diane?
It is important to tell your health care specialist what medicines you are already taking including those bought with prescription or without a prescription and herbal medicines, before you begin taking this medicine. Similarly, check with your health care specialist before taking any new medicines while using this one, to make sure that the combination drug is safe for your health.
When should Diane not be used?
You should not take Diane 35 mg if you:
- are allergic to ethinyloestradiol or cyproterone or any of the ingredients in Diane 35 tablets
- are pregnant or planning to become pregnant
- are taking another form of oral contraception
- have a past or family history of endometrial carcinoma or liver disease, carcinoma of the breast
- have high blood pressure, migrane
- have had deep venous thrombosis, heart attack or stroke
- have diabetes with changes to the blood vessels
- are taking other medications that may interact with Diane 35, such as anticonvulsants like carbamazepin and phenytoin, barbiturates, anti-infectives like rifabutin, nevirapine, rifampicin, the antifungal griseofulvin, antibiotics like penicillin, preparations containing St John's Wort
How should Diane – 35mg be used?
You should take your Diane 35 swallowed whole with a glass of water once daily at the same time each day and follow the instructions provided. For information about administration of medicines please consult your health care specialist.
How long you should use Diane?
You should take Diane 35 mg continually to ensure effective contraception and for as long as your health care specialist recommends. You should expect your acne to clear up entirely within a few months, but in particularly severe cases treatment for longer may be necessary before the full benefit is seen. You may be advised to keep taking your Diane 35 mg tablets for a few more months after the acne has disappeared and you should then change to another oral contraceptive.
Missed dose of Diane
In case if you miss a dose, consume a dose as soon as you notice. If you are close to the time for your next dose, wait until then and then consume your medicine. Never consume extra medicine to make up for a dosage that you have missed. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your health care specialist to discuss changes in schedule or a new schedule to make up for missed medicines, if you have missed too many doses in the recent pastime.
How should Diane- 35mg be stored?
- Store at 25 C
- Keep Diane tablets in their calendar pack until use
- Keep medicines away from the sight of children’s and pets
- Away from sun – light, heat, and moisture