Fluka 150mg
Available Dosages
| SKU | 429 |
|---|---|
| Generic For | Diflucan |
| Strength | 150 mg |
| Active Ingredient | Fluconazole |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 1.50 | US$ 45.0037%US$ 72.00 | |||
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| 60 Tablet/s | US$ 1.50 | US$ 90.0037%US$ 144.00 | |||
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| 90 Tablet/s | US$ 1.44 | US$ 130.0040%US$ 216.00 | |||
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Fluka 150mg – Affordable Diflucan Alternative for Fungal & Yeast Infections
Fluka 150mg is a well-established antifungal medication used to prevent and treat candidiasis and other fungal infections. Fluka contains Fluconazole as its active ingredient and is available as a prescription oral tablet. It is relied upon by physicians worldwide for its potent, broad-spectrum antifungal activity and its convenient dosing schedule, which often requires only a single tablet for uncomplicated vaginal yeast infections.
What is Fluka 150mg?
Fluka 150mg is an oral antifungal tablet containing 150mg of Fluconazole. It belongs to the triazole class of antifungals and is particularly effective against Candida species, the most common cause of fungal infections in humans. Candidiasis can affect the vagina (vaginal thrush), mouth and throat (oral thrush), oesophagus, lungs, blood, and other organ systems in immunocompromised individuals. Fluka is also effective against Cryptococcus neoformans, the causative agent of cryptococcal meningitis, a life-threatening infection in patients with HIV.
Manufacturer: Cipla is one of the world's most respected generic pharmaceutical manufacturers, and its Fluka 150 mg and fluconazole products meet stringent quality standards.
Fluconazole – The active ingredient & how does it work?
The active ingredient in Fluka 150mg is Fluconazole, used for fungal infections. It works by selectively inhibiting the fungal enzyme lanosterol 14-alpha-demethylase, which is essential for ergosterol biosynthesis, a critical component of the fungal cell membrane. Without adequate ergosterol, the fungal cell membrane becomes structurally compromised, leading to increased permeability, cell dysfunction, and ultimately cell death. Fluconazole is fungistatic at lower concentrations and fungicidal at higher concentrations. Because ergosterol is specific to fungal cells (human cells use cholesterol instead), Fluconazole exerts targeted action against fungi with minimal impact on human cell membranes.
Clinical uses of Fluconazole
Fluka 150mg is indicated for the treatment and prevention of a wide range of fungal infections, including vaginal candidiasis (vaginal yeast infection), oropharyngeal and oesophageal candidiasis (oral thrush), systemic candidiasis including candidaemia, peritonitis, and pneumonia, cryptococcal meningitis, and tinea infections of the body or scalp caused by dermatophytes. It is also used as prophylaxis in immunocompromised patients, such as those who have undergone bone marrow transplants, who are at high risk of developing serious fungal infections. The drug is effective for both short-term and long-term antifungal therapy.
Brand vs generic differences
Fluka 150mg is the generic equivalent of Diflucan, the original branded fluconazole product developed by Pfizer. Both products contain the same active ingredient, Fluconazole 150mg, and are bioequivalent. The clinical outcomes with Fluka are identical to those with Diflucan. The primary distinction is price: Diflucan carries a significant brand premium, whereas Fluka from Cipla is available at a substantially reduced cost. Patients who have previously used Diflucan can switch to Fluka with confidence.
Related strengths & products: Similar antifungal products include Forcan 200mg, Zocon DT 50mg and Zocon DT 100mg.
Key benefits of Fluka 150mg
Fluka 150mg offers several distinct advantages in antifungal therapy. Its once-weekly or single-dose regimen for vaginal candidiasis provides excellent patient compliance compared to topical creams that require daily application for days. Fluconazole is highly bioavailable after oral administration, achieving effective tissue concentration throughout the body, including tissues that are difficult to penetrate with other antifungals. It is effective against both vaginal and systemic forms of candidiasis. The drug has a well-documented safety record and is listed on the WHO Model List of Essential Medicines.
Precautions, warnings and drug interactions of Fluconazole pills
Fluka or Diflucan should not be taken by patients who are allergic to Fluconazole or other azole antifungals. There is limited evidence on its safety in pregnancy, and it should only be used when the potential benefit clearly outweighs the risk; inform your doctor if you are pregnant or planning to become pregnant. Fluconazole is excreted in breast milk and may cause side effects in nursing infants; breastfeeding mothers should discuss this risk with their doctor. The drug is not recommended for children under six months of age. Patients with pre-existing liver disease, diabetes, cardiac arrhythmias, or conditions that weaken the immune system should inform their doctor before starting treatment, as adjustments or additional monitoring may be needed. Fluconazole has a significant number of drug interactions, particularly with medications metabolised by the CYP450 enzyme system. Notable interactions include warfarin (increased bleeding risk), phenytoin, cyclosporine, rifampicin, terfenadine, and cisapride. A comprehensive medication review with your doctor is essential before starting Fluka.
Side effects of Fluconazole pills
Fluka 150mg or Diflucan is generally well tolerated when taken at standard doses. The most common side effects include headache, nausea, abdominal pain, stomach discomfort, diarrhoea, flatulence, and altered taste perception. These effects are typically mild and transient. Some patients may notice changes in how food tastes during treatment, which resolve once therapy is completed. Serious but rare side effects include hepatotoxicity (liver damage), which may present as dark urine, pale stools, jaundice (yellowing of the skin or eyes), or persistent nausea and vomiting; these symptoms require immediate medical evaluation. Severe dermatological reactions, such as Stevens-Johnson syndrome or toxic epidermal necrolysis, are extremely rare but serious and necessitate prompt discontinuation of the drug and emergency medical care. A rash during treatment, even if mild, should be reported to a doctor.
Benefits of buying Fluka 150mg online
Purchasing Fluka 150mg online is both convenient and cost-effective. Online prices are significantly lower than those at local pharmacies for the same Cipla-manufactured product. For women managing recurrent vaginal candidiasis, ordering online provides a discreet and private way to obtain medication without repeated visits to a pharmacy. PremiumRxDrugs offers genuine Cipla products, ensuring quality and efficacy. Larger pack sizes are available for patients requiring prophylactic or long-term antifungal therapy, with additional savings for bulk orders. Prescription uploads are straightforward, and doorstep delivery ensures treatment is never interrupted by pharmacy availability.
Dosage, administration & storage information for Fluconazole pills
The dosing of Fluka or Diflucan varies depending on the type and severity of the fungal infection. For uncomplicated vaginal candidiasis, a single 150mg tablet is typically sufficient. For oropharyngeal candidiasis, the usual dose is 200mg on the first day, followed by 100mg once daily for at least 14 days. For systemic infections, higher doses and longer treatment durations may be required, as determined by the treating physician. Fluconazole pills are taken orally, with or without food. It should be swallowed whole with a glass of water. In older patients, the kidneys may not clear the medication efficiently, prolonging its half-life and increasing the risk of side effects. Doctors may therefore prescribe a lower dose for elderly patients. Do not alter the prescribed dose without medical advice. Missed doses should be taken as soon as they are remembered, unless the next dose is imminent.
Store Fluka at room temperature (below 30°C), away from direct sunlight and moisture. Keep out of reach of children.
What is Fluka 150mg used for?
Fluka 150mg contains fluconazole 150mg — the single-dose formulation for vaginal candidiasis (thrush). A single oral 150mg tablet is the standard treatment for uncomplicated acute vaginal candidiasis — convenient, highly effective (85–90% cure rate), and eliminates the need for intravaginal preparations. It is also used for recurrent vaginal candidiasis as maintenance therapy (150mg weekly for 6 months reduces recurrence from 50–70% to <10%). The 150mg single-dose treatment is one of the most widely prescribed antifungal regimens globally due to its simplicity and effectiveness.
How does a single dose of Fluka 150mg treat vaginal thrush?
A single 150mg fluconazole dose achieves peak plasma concentrations of ~2.5 micrograms/mL within 1–2 hours, with vaginal tissue concentrations remaining above the MIC for Candida albicans for 72–96 hours due to fluconazole's 30-hour plasma half-life and excellent tissue penetration. This sustained exposure eliminates the majority of vaginal Candida over 3–4 days. Clinical response is usually apparent within 24–48 hours of the single dose. Complete symptom resolution (itch, discharge, discomfort) typically occurs within 3–7 days. For severe or recurrent infection, a second 150mg dose 3 days after the first improves cure rates.
How should Fluka 150mg be taken for vaginal thrush?
Uncomplicated vaginal candidiasis: take one Fluka 150mg tablet as a single dose — at any time of day, with or without food. No follow-up doses are needed for uncomplicated infection. Severe vaginal candidiasis: repeat a second 150mg dose after 72 hours. Recurrent vaginal candidiasis (4+ epiSodiumes/year): 150mg weekly for 6 months as maintenance suppressive therapy — dramatically reduces recurrence frequency. Partners of women with vaginal candidiasis generally do not require treatment unless they have symptomatic penile candidiasis (balanitis). Pregnancy: fluconazole single dose should be avoided in the first trimester — use intravaginal clotrimazole instead.
Is Fluka 150mg safe during pregnancy for vaginal thrush?
Single-dose fluconazole 150mg should be avoided during pregnancy — particularly in the first trimester. Recent epidemiological studies report a possible association between repeated high-dose oral fluconazole in pregnancy and increased risk of spontaneous abortion and rare foetal cardiac defects (tetralogy of Fallot). A single 150mg dose is lower risk but most guidelines recommend using intravaginal azole therapy (clotrimazole, miconazole pessaries for 7 days) as the safer first-line treatment for vaginal candidiasis in pregnancy — avoiding oral fluconazole entirely. For systemic or refractory fungal infections in pregnancy, specialist infectious disease advice is essential.
What drug interactions affect Fluka 150mg single dose?
Even a single 150mg dose has clinically meaningful CYP2C9/3A4 inhibitory effects lasting 2–3 days. Key interactions: warfarin — single-dose fluconazole can increase INR significantly; recheck INR 3–4 days after single dose; sulfonylureas — hypoglycaemia risk for 2–3 days after dose; phenytoin — levels transiently increase; statins (simvastatin) — transient increase; QT-prolonging drugs — monitor ECG if combined; tacrolimus/ciclosporin — transient level increases. For a single dose in most patients with no major interacting drugs, significant adverse effects from interactions are uncommon — but prescribers must be aware, especially in anticoagulated patients.
How does Fluka 150mg compare to topical clotrimazole for vaginal thrush?
Oral fluconazole 150mg single dose and topical clotrimazole (1% cream or 500mg pessary single application) treat uncomplicated vaginal candidiasis with equivalent 85–90% cure rates. The oral route is preferred by most women for convenience and simplicity — one tablet vs. intravaginal application. Clotrimazole is preferred in: pregnancy (safer), patients on multiple interacting medications, and those who prefer topical therapy. Both approaches are appropriate first-line choices. For recurrent or severe infection, oral fluconazole maintenance therapy (weekly for 6 months) is more practical than weekly topical courses.
Is Fluka 150mg equivalent to Diflucan 150mg?
Yes. Fluka 150mg and branded Diflucan 150mg both contain fluconazole 150mg in bioequivalent formulations. Fluka is the generic alternative providing the same single-dose vaginal thrush treatment as Diflucan at significantly lower cost.
Can I order Fluka 150mg from PremiumRxDrugs for international delivery?
Yes. PremiumRxDrugs.com ships Fluka 150mg to the USA, UK, Australia, and many other countries. Our genuine manufacturer-verified antifungal medications, competitive pricing, and free worldwide shipping on qualifying orders make us a reliable international source for fluconazole single-dose therapy.
What side effects does Fluka 150mg cause with single-dose use?
Single 150mg dose is very well tolerated. Common: mild headache, nausea, and abdominal discomfort — typically lasting only hours. Metallic taste and dizziness occasionally. Rash rarely. Serious reactions (hepatotoxicity, severe rash) are extremely rare with single-dose therapy. The side effect profile is substantially milder than multi-day fluconazole courses. If symptoms of thrush worsen or do not improve within 7 days, a second fluconazole dose or specialist gynaecological assessment is warranted. In HIV-positive women or diabetic women, single-dose therapy may be less effective — a 3-day or weekly course may be needed.
Can Fluka 150mg cause vaginal thrush resistance over time?
Repeated fluconazole use for vaginal candidiasis can select for resistant Candida species — particularly Candida glabrata (inherently less susceptible to fluconazole) and acquired resistance in Candida albicans. Risk is higher with recurrent use and lower with infrequent single-dose epiSodiumic treatment. Signs of fluconazole resistance: recurrent treatment failure (symptoms not resolving after standard doses). If suspected, Candida speciation and sensitivity testing by vaginal swab is warranted. Resistant candidiasis is managed with: higher-dose extended fluconazole courses, boric acid intravaginal (locally available), or alternative triazoles/echinocandins under specialist guidance.
How soon after Fluka 150mg will vaginal thrush symptoms improve?
Most women notice significant symptom improvement (reduced itch, discharge, and discomfort) within 24–48 hours of taking a single Fluka 150mg tablet. Complete symptom resolution typically occurs within 3–7 days. Vulval soreness and skin inflammation may take a few additional days to fully resolve after the infection is treated. If symptoms are not significantly better within 7 days, a second 150mg dose 3 days after the first may be needed, or reassessment by a gynaecologist to confirm Candida diagnosis (other infections can cause similar symptoms — bacterial vaginosis and sexually transmitted infections may require different treatments).
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