Glizid 80mg
Available Dosages
| SKU | 484 |
|---|---|
| Generic For | DIAPREL |
| Strength | 80mg |
| Manufacturer | Panacea (India). |
| Active Ingredient | Gliclazide |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.38 | US$ 11.50 | |||
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| 60 Tablet/s | US$ 0.31 | US$ 18.5020%US$ 23.00 | |||
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| 90 Tablet/s | US$ 0.27 | US$ 24.0030%US$ 34.50 | |||
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Glizid 80mg – Affordable DIAPREL Alternative for Type 2 Diabetes
Glizid 80mg is a medicine used to control blood glucose in people with type 2 diabetes. It is given as an adjunct with diet and exercise to keep control over high blood sugar levels in type 2 diabetes mellitus. This significantly reduces the effects of the body's chronically elevated sugar levels. It helps in reducing the risk associated with cardiovascular diseases, stroke and kidney-related problems.
The active ingredient of the medicine is Gliclazide, an oral antihyperglycemic agent specifically formulated to treat non-insulin-dependent diabetes mellitus (type 2 diabetes) in adults when dietary and physical measures, and weight loss alone, are not adequate to control blood glucose. The hypoglycaemic action of the antidiabetic medicine is related to increased insulin secretion from functioning beta cells in the pancreas. It increases insulin release and improves insulin dynamics. Gliclazide is believed to be rapidly absorbed from the gastrointestinal tract.
Precautions and warnings
Disturbance in blood sugar levels (sometimes high and sometimes low) can occur when Glizid 80 mg is prescribed alongside antibiotics, including Fluoroquinolones, especially in elderly patients. In such a case, you may be asked to pay attention to regular monitoring of blood glucose. If you have a family history or know you are suffering from a hereditary condition related to abnormality in red blood cells (glucose-6-phosphate dehydrogenase deficiency), contact your healthcare specialist before taking this medication. Avoid the consumption of alcohol while using this medication. Let your healthcare specialist know if you are taking certain medications during Glizid treatment. The blood glucose-lowering effect of Gliclazide may be greater, and symptoms of low blood sugar levels may occur when any of the following medications are taken:
- Antibiotics (sulphonamides, clarithromycin)
- Antifungal medications (fluconazole, miconazole)
- Antidiabetic agents (oral antidiabetics, GLP-1 receptor inhibitors or insulin)
- Medicines to treat high blood pressure or heart failure (antiarrhythmias, beta blockers, ACE inhibitors).
- Medicines to treat ulcers in the stomach or duodenum (H2 receptor antagonists)
- Antirheumatics or pain killers (ibuprofen, phenylbutazone)
- Medications to treat depression (monoamine oxidase inhibitors).
- Medications containing alcohol
You should not take Glizid 80 mg if you have:
- Liver-related problems
- Type 1 diabetes
- Pregnancy or planning to become pregnant
- Breastfeeding
- Kidney-related problems
- Have diabetes ketoacidosis
- Allergic to sulfonylurea/sulfonamides or any other inactive components of the medication.
The antidiabetic medicine is not recommended for use in children.
What are the side effects of Glizid 80mg?
Glizid 80 mg is very effective and potent antidiabetic drug. Every drug possesses some side effects, same goes with the Gliclazide. Following are the associated side effects:
- Gastrointestinal disturbances such as diarrhea, nausea, constipation and vomiting
- Bloating (intense feeling of full and tight abdomen)
- Skin reactions like urticaria, pruritis, rashes, hives and flushing
- Headache and dizziness
- Bleeding associated problems like bruising, Sore throat and paleness
- Yellowing of eyes and skin
- Vision problems
Changes in external factors, such as lifestyle, weight reduction, stress, or improvements in blood sugar levels, may require adjustments to gliclazide doses. This usually depends on the response to treatment. Only a healthcare specialist can determine the most suitable dose for you. It is not possible to fix the dose. A person's body weight, health status, disease severity, and age are among the factors considered when recommending a dose. Glizid is generally taken once a day. When the total daily dose exceeds 2 tablets, it should be divided into 2 equal doses, taken in the morning and evening, under the supervision of a healthcare specialist. Swallow your tablet whole with a glass of water. Avoid chewing them. You must always eat a meal before taking this antidiabetic medicine. If you notice your blood sugar levels are high despite taking the medicine as prescribed by your healthcare specialist. While taking this antidiabetic medication, it is important to eat regular meals, including breakfast, and never miss or delay a meal, especially breakfast. Keep a close eye on your blood glucose regularly as recommended by yoru healthcare provider.
If an overdose occurs, immediately consult with your concerned healthcare specialist. Take medical help as soon as possible if you encounter a hypoglycemia state. Perform gastric lavage immediately and administer intravenous glucose to counteract hypoglycemia. Try to take the medicine at the same time each day; this reduces the chances of missing a dose. Consult your healthcare specialist if you miss a dose. Don't double the dose to make up for the missed one.
What is Glizid 80mg used for?
Glizid 80mg contains gliclazide 80mg — the standard single-dose strength of this second-generation sulfonylurea for type 2 diabetes. At 80mg, it provides greater insulin secretory stimulation and HbA1c reduction than the 40mg starting dose. It may be prescribed once or twice daily (up to 160mg/day) based on glycaemic response. Gliclazide 80mg is particularly valued for its antioxidant properties, cardiovascular safety record from the ADVANCE trial, and relatively favourable hypoglycaemia profile compared to older sulfonylureas.
How effective is Glizid 80mg at lowering HbA1c?
Gliclazide 80mg taken twice daily (160mg/day) typically reduces HbA1c by 1.0–2.0% from baseline, depending on initial glucose levels and residual beta-cell function. The ADVANCE trial demonstrated that intensive glycaemic control with gliclazide MR-based therapy (targeting HbA1c ≤6.5%) significantly reduced microvascular complications (nephropathy, retinopathy). Standard-release gliclazide 80mg twice daily provides similar overall glucose control to gliclazide MR 30–60mg once daily.
How should Glizid 80mg be taken correctly?
Glizid 80mg (standard-release) is taken once or twice daily with meals. The most common regimen: 80mg with breakfast, 80mg with the evening meal (160mg total daily dose). Maximum dose is 160–320mg/day in divided doses. Take consistently with the same meal each day. Never take on an empty stomach. If blood glucose targets are not achieved at 80mg twice daily, dose escalation or adding a second agent (metformin) is preferred over exceeding 320mg/day. Monitor fasting and post-prandial glucose to assess adequacy.
Is gliclazide 80mg suitable for patients with mild kidney disease?
Gliclazide is among the safer sulfonylureas in mild-to-moderate CKD. Unlike glibenclamide, gliclazide is inactivated by the liver to inactive metabolites, reducing accumulation risk in CKD. At eGFR 30–60 ml/min (mild-moderate CKD), gliclazide can generally be used with careful monitoring. Below eGFR 30 ml/min, the risk of hypoglycaemia increases and most guidelines recommend avoiding sulfonylureas, switching to DPP-4 inhibitors or insulin. Regular eGFR monitoring is essential in all CKD patients on sulfonylureas.
How does gliclazide 80mg compare to gliclazide MR 60mg?
Gliclazide 80mg (standard-release, twice daily) and gliclazide MR 60mg (modified-release, once daily) provide similar overall glycaemic control. The MR formulation offers the significant practical advantage of once-daily dosing — improving adherence. Modified-release also produces a more sustained, lower-peak insulin secretion pattern, which may slightly reduce hypoglycaemia risk. Many guidelines prefer gliclazide MR over standard-release for this reason. Where gliclazide MR is not available or is more expensive, standard-release 80mg twice daily remains an effective alternative.
What should I do if I miss a Glizid 80mg dose?
If you miss a Glizid 80mg dose with a meal and you are still within an hour of that meal, take the dose immediately with food. If the meal time has already passed significantly, skip the missed dose and take the next scheduled dose with the next meal — never double dose. Doubling the dose increases hypoglycaemia risk for the following hours. Blood glucose monitoring after a missed dose helps assess whether any correction is needed. Regular adherence is critical — missed doses lead to glucose fluctuations and suboptimal HbA1c control.
How does Glizid 80mg compare to metformin 500mg for newly diagnosed type 2 diabetes?
Metformin is the universally recommended first-line agent for type 2 diabetes in most international guidelines — it is weight-neutral, has cardiovascular benefit (UKPDS), and does not cause hypoglycaemia. Gliclazide 80mg is a second-line addition when metformin alone is insufficient, or a first-line alternative when metformin is contraindicated or not tolerated. Both produce similar HbA1c reductions (1.0–2.0%), but the superior safety and metabolic profile of metformin makes it the preferred starting point in new diagnoses.
Is Glizid 80mg the same as Diamicron 80mg?
Yes. Glizid 80mg contains gliclazide 80mg — the same active ingredient and dose as branded Diamicron 80mg. Both provide equivalent insulin secretory stimulation and HbA1c reduction. Glizid is the generic formulation at a substantially lower cost than branded Diamicron — making consistent, long-term diabetes therapy affordable.
Can I order Glizid 80mg from PremiumRxDrugs with delivery to Australia?
Yes. PremiumRxDrugs.com ships Glizid 80mg and other diabetes medications to Australia, the USA, UK, and many other countries. Their genuine manufacturer-verified medicines, transparent pricing, and free worldwide shipping on qualifying orders make them a trusted international source for patients managing type 2 diabetes with sulfonylurea therapy.
What are the side effects of Glizid 80mg?
Hypoglycaemia is the main concern — at 80mg (and especially 160mg/day), blood glucose can fall too low if meals are delayed or skipped. Symptoms: sweating, shakiness, hunger, confusion. Weight gain (1–3 kg) is typical with consistent sulfonylurea use. GI effects (nausea, heartburn) are occasional. Skin rash, photosensitivity, and rarely, blood count changes and liver enzyme elevations have been reported. Hypoglycaemia requiring third-party assistance should be reported to your doctor — dose reduction may be needed.
What precautions are important with Glizid 80mg?
Always eat with or just after taking the dose. Carry glucose tablets. Monitor blood glucose regularly. Avoid alcohol excess. Reduce or hold dose during illness with poor food intake. Inform your doctor of any new medications — many common drugs (fluconazole, clarithromycin, NSAIDs, ACE inhibitors) can potentiate gliclazide's effect. Annual eGFR, liver function, and HbA1c review. In the elderly, use the lowest effective dose and consider switching to gliclazide MR for simpler once-daily dosing.
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