Graniset 1 mg (Granisetron)
Graniset is supplied in the form of tablets for oral administration. It effectively eliminates retching and vomiting evoked by cytotoxic chemotherapy agents. Its active component is Granisetron, which functions by inhibiting the natural substance called serotonin in the body that is responsible for nausea and vomiting. It falls into the category of drugs known as antiemetics. This medicine is only recommended for use in adults.
What is Graniset used for?
Graniset is formulated to prevent nausea and vomiting due to emetogenic radiotherapy and chemotherapy. It effectively prevents and treats postoperative nausea and vomiting. It can also be prescribed to you for some other purposes not mentioned in this document. In the case of any doubt, please consult with your physician.
How does Granite work?
Graniset comprises of an active component Granisetron, which exerts its properties by blocking the effects of serotonin receptor sites present in vagal nerve terminals and the chemoreceptor trigger zone in the central nervous system. The activity decreases incidence and severity of nausea and vomiting following radiation therapy, emetogenic chemotherapy or surgery.
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What does Graniset contain?
Graniset contains the active ingredient Granisetron, which is a 5-HT3 receptor antagonist. Each tablet delivers 1 mg of the beneficial ingredient to the patients.
What are the side effects of Graniset?
Side effects that need to be reported to your physician as soon as possible are as follows:
- Trouble breathing
- Low balance of coordination
- Fast or irregular heartbeat
- Unusually weak or tired
The unwanted effects that do not require medical help include a headache, diarrhea, and constipation.
What medications interact with Graniset?
Avoid consuming Graniset with the following medications:
- Certain medicines to treat fungal infections like posaconazole, fluconazole, ketoconazole, voriconazole, itraconazole.
This drug may interact with some other drugs also and may affect the pharmacokinetics of many drugs. Some of them are given below.
- Methylene blue
- Monoamine oxidase inhibitors such as Nardil, Marplan, carbex, Parnate, and Eldepryl
- Other medications that can cause an abnormal heart rhythm.
When should Graniset not be used?
- Use of Graniset is not recommended for patients who are allergic to Granisetron or other inactive ingredients of the formulation.
- It is not suitable for neonates
Exercise caution while taking Granisetron tablets during the following condition:
- Pediatrics above two years of age
- Arrhythmias or conduction disorders
How should Graniset be used?
Take it by mouth with a glass full of water. Follow all the instructions on your prescription label. Do not consume your medicine more than the recommended amount. The recommended dose is 2 mg once a day or 1 mg twice a day. The medicine is available in the form of tablets for oral use. Its dosage varies from patient to patient. It depends on various factors such as weight, age, sex, and condition of the patient. Your physician will be the right person to tell you how much medicine to take or what amount of the drug is required to treat or prevent the disease.
How long should you use Graniset?
Continue taking Graniset 1 mg for as long as recommended to you. You should follow the accompanying patient information carefully for the proper use of the medicine and succeed in achieving maximum improvement. You are not allowed to exceed the prescribed dose.
Missed dose of Graniset
The chances of missing a dose are almost nil as the medicine is only taken on the days when chemotherapy and radiotherapy are given.
How should Graniset be stored?
- Keep out of the reach of children
- Place it away from heat and moisture
- It should be protected from direct light
- Keep the tablets at controlled temperature