Brufen 400mg
Available Dosages
| SKU | 529 |
|---|---|
| Generic For | Motrin |
| Strength | 400mg |
| Manufacturer | Abbott Healthcare |
| Active Ingredient | Ibuprofen |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 40 Tablet/s | US$ 0.25 | US$ 10.00 | |||
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| 60 Tablet/s | US$ 0.19 | US$ 11.4024%US$ 15.00 | |||
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| 100 Tablet/s | US$ 0.15 | US$ 15.0040%US$ 25.00 | |||
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Brufen 400mg (Ibuprofen) – Affordable Motrin Alternative
Brufen 400 mg consists of main ingredient Ibuprofen is a non-selective inhibitor of COX-1 and COX-2. Ibuprofen inhibits thromboxane B2 release and anandamide metabolism. The medicine provides relief by changing the way the body responds to pain, and high temperature. Ibuprofen is the main medicinal substance contained in the Ibugesic tablets.
What is Brufen used for?
Brufen 400mg is used to relieve pain, swelling, stiffness, and tenderness caused by osteoarthritis and rheumatoid arthritis. It is also used to relieve mild to moderate pain, menstrual pain (pain that occurs before or during menstrual period). The drug is also used to reduce fever, and to relieve minor aches. Muscle aches, , arthritis, headaches, toothaches, the common cold, and backaches.
How does Brufen work?
Brufen 400 mg is a selective cyclooxygenase 2 enzyme inhibitor. It selectively gets adhere to the enzyme receptor, and stops the conversion of the arachidonic acid to prostaglandin that is a precursor of the inflammatory mediators. Prostaglandins are the chemicals that produce an inflammatory response like, fever, swelling, pain, and tenderness. The medicine stops the inflammation and gives symptomatic relief. To treat your pain, buy Ibugesic 400 mg online.
What medications interact with Brufen 400mg?
Avoid consuming Ibugesic, if you are taking the medicines that are given below:
- Fluconazole
- Furosemide
- Warfarin
- Aspirin
- Prednisone
- Lithium
- Enalapril
- Benazepril
- Irbesartan
- Candesartan
- Olmesartan
- Losartan
- Methotrexate
When should Brufen 400mg not be used?
Tell the doctor, before consuming Ibugesic:
- If you are hypersensitive to the drug, or its components.
- If you have ulcers of stomach.
- If you have kidney disorders.
- If you have liver problems.
- If you smoke.
- If you observe a small growth with a stalk, sticking out from a mucous membrane.
- If you have asthma.
- If you suffer from convulsions.
- If you are prone to allergies,
- If you have bleeding problems.
- If you have increased cholesterol level.
- If you have hypertension.
- If you have a history of blood clot, heart attack, or stroke.
- If you are suffering from Sjogren’s syndrome.
- If you are a woman of child bearing potential. You should discuss the positives and negatives of taking Ibuprofen, at the time of pregnancy.
- Breastfeeding women are advised not to take Ibugesic as it may pass into breast milk and harm the nursing baby.
How should Brufen 400mg be stored?
- Do not forget to see the expiry date of the product.
- Store the tablet in a dry place and out of direct light.
- It should be stored at a room temperature.
- Always keep the written record of your medications.
- Place the drug away from infants.
- Do not share your medicines with your near and dear ones.
What are the side effects of Brufen 400mg?
Like other medicines, Ibugesic may cause adverse effects. Seek medical attention, in case the following troubles arise:
- Ringing in your ears
- Mild skin rashes
- Constipation
- Mild heartburn
- Bloating
- Flatulence
- Sore throat
- Fatigue
- Stuffy nose
- Diarrhea
- Gas
- Dizziness
- Coughing
- Nausea
- Nervousness
The adverse reactions of Ibugesic can be dangerous also. Visit the doctor immediately, in the following situations.
- Decreased urine output
- Discomfort, and pain in the abdomen
- Changes in your vision
- Extreme weakness
- Rapid weight gain
- Restlessness
- Dark urine
- Appearance of blood in coughs
- Vomits with blood
- Bloody or tarry stools
- Loss of appetite
- Symptoms of Flu
- Yellowing of eyes, and skin
- Swelling
- Shortness of breaths
- Convulsions
- Insomnia
How should Brufen 400mg be taken?
- Brufen 400 mg is present in the form of tablets. To get rid of stomach problems, take the tablet with a meal. Swallow the tablet with an adequate amount of water.
- The intake of dosage depends upon your health situation. Consume the tablet in the same way as suggested to you. Don’t alter the dosage plan
- Consume the tablet daily, at the same interval of time.
- Overdose: Seek medical attention immediately, in the case of an accidental overdose of Ibuprofen. Symptoms of an overdose include:
- Fainting
- Nausea
- Drowsiness
- Shallow breathing
- Stomach pain
- Vomiting
- Bloody stools
- Coma
Missed Dose of Brufen 400mg
If you have forgotten a dose, take it as soon you remember and go back to your usual dosing schedule. If the time to take the next dose is near, leave the forgotten dose and take the next dose. Do not double up the dose to compensate the forgotten one.
- Take the tablet for as long as your doctor recommended.
What is Ibuprofen and what conditions does it treat?
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) widely used to relieve pain, reduce inflammation, and lower fever. Brufen 400mg contains ibuprofen as its active ingredient and effectively treats headaches, dental pain, menstrual cramps, muscle aches, arthritis, and minor injuries. This pain reliever works by blocking chemicals in the body that cause inflammation and discomfort. As an over-the-counter and prescription-strength NSAID, ibuprofen provides relief for both acute pain epiSodiumes and chronic inflammatory conditions when used appropriately.
How does Ibuprofen work in the body?
Ibuprofen works by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which are responsible for producing prostaglandins. Prostaglandins are chemical messengers that trigger inflammation, pain signals, and fever in the body. When you take Brufen 400mg, the ibuprofen blocks these enzymes, reducing prostaglandin production and thereby decreasing swelling, relieving pain, and lowering elevated body temperature. This mechanism makes it an effective anti-inflammatory medication for various painful conditions, from sports injuries to arthritis flare-ups.
How long does Brufen 400mg take to work?
Brufen 400mg typically begins to work within 20 to 30 minutes after ingestion, with peak pain relief occurring around one to two hours later. For fever reduction, you may notice effects within the first 30 minutes. The speed at which this ibuprofen tablet works depends on whether you take it on an empty or full stomach—absorption is faster without food. The pain-relieving and anti-inflammatory effects usually last four to six hours, which is why dosing is commonly recommended every four to six hours as needed.
When and how should I take Brufen 400mg?
Take Brufen 400mg with food or milk to minimize stomach upset, as ibuprofen can irritate the gastric lining. Swallow the tablet whole with a full glass of water. The typical adult dose is one tablet every four to six hours as needed, not exceeding three tablets in 24 hours unless directed by your healthcare provider. For best results with inflammatory conditions like arthritis, take this NSAID at regular intervals. Avoid lying down for at least 10 minutes after taking the medication to prevent esophageal irritation.
Is Brufen 400mg safe for long-term use?
Brufen 400mg is generally intended for short-term pain and inflammation management rather than prolonged continuous use. Extended use of ibuprofen increases risks of gastrointestinal problems including ulcers and bleeding, cardiovascular events, and kidney damage. If you need this NSAID for chronic conditions like arthritis beyond two weeks, medical supervision with regular monitoring is essential. Your doctor may recommend the lowest effective dose for the shortest duration necessary, possibly combined with stomach-protective medications. Always discuss long-term pain management strategies with your healthcare provider to balance benefits against potential risks.
Can I take Brufen 400mg with other medicines?
Brufen 400mg can interact with numerous medications, so inform your doctor about all drugs you're taking. This ibuprofen formulation may interact with blood thinners like warfarin, increasing bleeding risk, and with other NSAIDs or aspirin, raising gastrointestinal side effect likelihood. It can reduce effectiveness of blood pressure medications and ACE inhibitors, and may interact with antidepressants, corticosteroids, and lithium. Combining ibuprofen with certain diuretics can affect kidney function. Always check with your pharmacist or healthcare provider before combining Brufen with prescription or over-the-counter medications, including herbal supplements.
How does Brufen 400mg compare to other NSAIDs like naproxen or aspirin?
Brufen 400mg contains ibuprofen, which works faster than naproxen but has a shorter duration of action, requiring more frequent dosing. Naproxen lasts eight to twelve hours compared to ibuprofen's four to six hours. Compared to aspirin, ibuprofen is a more potent anti-inflammatory with fewer gastrointestinal side effects at equivalent doses. Unlike aspirin, this NSAID doesn't provide cardiovascular protection. Ibuprofen is often preferred for acute pain and fever, while naproxen suits conditions requiring sustained inflammation control. Individual response varies, so effectiveness depends on your specific condition and personal tolerance.
Is generic Ibuprofen as effective as branded Brufen?
Generic ibuprofen is therapeutically equivalent to branded Brufen 400mg, containing the same active ingredient at identical strength and meeting the same regulatory standards for safety, quality, and efficacy. Pharmaceutical regulators require generics to demonstrate bioequivalence, meaning they work in the body the same way as brand-name versions. The main differences lie in inactive ingredients, packaging, and price—not effectiveness. Whether you choose branded or generic ibuprofen tablets, the pain relief and anti-inflammatory benefits remain consistent. Many patients opt for generic versions due to cost savings without compromising treatment outcomes.
Why do patients choose PremiumRxDrugs.com for Brufen 400mg?
Patients prefer PremiumRxDrugs.com for Brufen 400mg because of guaranteed authentic medications sourced directly from manufacturers, competitive pricing that makes this NSAID affordable, and discreet packaging that protects privacy. We offers convenient worldwide shipping with free delivery options to the USA, UK, and Australia. With over ten years serving the international community, PremiumRxDrugs.com provides easy prescription management, straightforward reordering, and responsive customer support. Whether you need ibuprofen for occasional pain relief or ongoing inflammatory conditions, our licensed pharmacy combines reliability, affordability, and convenience in one trusted platform.
What are the common side effects of Ibuprofen?
Common side effects of ibuprofen include stomach upset, nausea, heartburn, dizziness, and mild headache. Some people experience gas, bloating, or diarrhea when taking this NSAID. Less common but notable effects include ringing in the ears, blurred vision, or swelling in the ankles and feet due to fluid retention. Taking ibuprofen with food typically reduces digestive discomfort. Most side effects are mild and temporary, resolving once your body adjusts or after discontinuing the medication. Serious reactions like severe stomach pain, black stools, chest pain, or allergic symptoms require immediate medical attention.
Who should avoid taking Ibuprofen?
Avoid ibuprofen if you have a history of allergic reactions to NSAIDs or aspirin, active stomach ulcers, severe heart failure, or advanced kidney disease. Pregnant women, especially in the third trimester, should not take this anti-inflammatory medication as it may harm the developing baby. People with uncontrolled high blood pressure, bleeding disorders, or those scheduled for heart surgery should avoid ibuprofen. Those with asthma may experience worsening symptoms. Children under certain ages and elderly individuals with multiple health conditions require careful evaluation before using this pain reliever. Always disclose your complete medical history to your healthcare provider.
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