Imat 400mg Tablet
| SKU | 2762 |
|---|---|
| Generic For | Imatinib |
| Manufacturer | Intas Pharma, India |
| Active Ingredient | Imatinib |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 10 Tablet/s | US$ 3.00 | US$ 30.0076%US$ 124.00 | |||
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| 30 Tablet/s | US$ 3.00 | US$ 90.0076%US$ 372.00 | |||
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| 60 Tablet/s | US$ 3.00 | US$ 180.0076%US$ 744.00 | |||
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| 90 Tablet/s | US$ 3.00 | US$ 270.0076%US$ 1,116.00 | |||
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| 120 Tablet/s | US$ 3.00 | US$ 360.0076%US$ 1,488.00 | |||
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Imat 400mg Tablet (Imatinib) – Generic Targeted Therapy for CML & GIST
Imat 400 mg tablets are targeted anticancer medicines widely used to treat certain blood cancers and tumours driven by abnormal protein activity. It contains Imatinib, which helps block specific signals responsible for the uncontrolled growth and multiplication of cancer cells.
Uses of Imat 400mg - One of its primary uses is the treatment of Chronic Myeloid Leukaemia (CML), a cancer that affects the blood and bone marrow. By targeting the abnormal BCR-ABL protein associated with this disease, Imat 400 mg helps control leukaemia cell growth and supports long-term disease management. The medication is also prescribed for Philadelphia chromosome-positive Acute Lymphoblastic Leukaemia (Ph+ ALL), where it helps reduce the spread of cancerous cells and improves treatment outcomes when used alone or in combination with other therapies. Another important use of the Imatinib 400 mg tablet is in the management of Gastrointestinal Stromal Tumours (GISTs), rare tumours that develop in the digestive tract.
Additionally, Imat 400 mg may be recommended for certain uncommon disorders, including myelodysplastic/myeloproliferative diseases, chronic eosinophilic leukemia, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.
Mechanism of action of Imatinib (The active component)
Imatinib 400 mg works by blocking abnormal tyrosine kinases, which play a critical role in the growth of certain cancer cells. In diseases such as CML, an abnormal gene produces a protein called BCR-ABL, which continuously signals cells to grow and divide without control. Imatinib specifically targets and inhibits this protein, helping slow or stop the growth of cancerous cells. The medicine also blocks other proteins such as KIT and platelet-derived growth factor receptors (PDGFR), which are involved in the development of gastrointestinal stromal tumours and certain rare blood disorders. By interfering with these disease-causing signals, Imat tablet helps reduce abnormal cell activity and supports better disease control while minimising damage to healthy cells.
Benefits of Imat 400 mg tablet
One of the major advantages of Imat 100 mg is its targeted mechanism of action. Instead of attacking all rapidly dividing cells, it specifically focuses on abnormal proteins involved in cancer development. This targeted approach often leads to improved treatment outcomes and may reduce some of the side effects commonly associated with traditional chemotherapy. The medication helps:
- Control the growth of cancer cells
- Slow disease progression
- Reduce tumour size in certain conditions
- Improve long-term survival rates
- Support a better quality of life
- Lower the risk of disease recurrence in selected patients
Many patients remain on treatment for extended periods and achieve significant disease control when the medication is taken consistently as prescribed.
PrepmiumRxDrugs offer authentic cancer medicines at affordable prices. Find the different strengths of Imatinib, a doctor-prescribed medication, after examining a patient. Check the running deals to save the best on your prescription treatment.
Precautions to be taken while using Imatinib tablets
Before starting treatment, patients should discuss their complete medical history with their healthcare provider. Special caution may be required in individuals with liver disease, kidney disorders, heart problems, or a history of fluid retention. Patients should inform their doctor if they are allergic to Imatinib or any of the tablet's ingredients. Any history of severe drug reactions should also be reported before beginning therapy.
Women who are pregnant or planning pregnancy should consult their physician before using Imat. Breastfeeding should be avoided unless specifically approved by a healthcare provider because the medicine may pass into breast milk. The medication can occasionally cause dizziness, fatigue, or blurred vision. Patients experiencing these effects should avoid driving or operating heavy machinery until they know how the treatment affects them. Regular blood tests are important during treatment because the medicine can affect blood cell counts and organ function.
Patients should immediately report symptoms such as persistent fever, unusual bruising, excessive bleeding, swelling, breathing difficulties, or yellowing of the skin and eyes. Patients should avoid self-adjusting the dosage or discontinuing treatment without medical advice, even if symptoms improve. Abruptly stopping therapy may affect disease control. Adequate hydration is recommended unless otherwise instructed by a healthcare provider. Special caution is advised when taking other prescription medicines, herbal products, or dietary supplements, as some may interfere with Imatinib's effectiveness or increase the risk of side effects. Women of childbearing potential should discuss reliable contraceptive measures with their doctor before and during treatment. Any signs of unusual bleeding, persistent fever, severe fatigue, yellowing of the skin or eyes, vision changes, or severe skin reactions should be reported immediately. Careful adherence to medical instructions and routine monitoring can help maximise the benefits of Imat 400 mg tablet while minimising potential risks.
Possible side effects of the Imatinib tablet
Like all medications, Imat 400 mg may cause side effects, although not everyone experiences them. Many side effects are mild and manageable, particularly during the early stages of treatment. Common side effects include nausea, vomiting, diarrhea, stomach discomfort, headache, fatigue, muscle cramps, joint pain, skin rash, and swelling around the eyes or ankles. Some patients may experience reduced appetite, dizziness, weakness, or changes in body weight. Abnormalities in blood tests for red blood cells, white blood cells, or platelets may also occur. More serious side effects, although less common, include severe allergic reactions, liver problems, significant fluid retention, bleeding disorders, heart complications, and severe infections. Patients should seek immediate medical attention if they experience chest pain, severe shortness of breath, persistent fever, yellowing of the skin, dark urine, or unexplained bleeding. Regular monitoring helps identify and manage side effects before they become severe.
Correct use of Imatinib tablets
The Imat 400 mg tablet should be used exactly as directed by a healthcare professional. The dosage varies depending on the patient's condition, body weight, treatment response, and overall health status. The tablet is usually taken with food and a full glass of water. Taking it with meals helps reduce stomach irritation and improves tolerability. The tablet should be swallowed whole and should not be crushed, chewed, or broken unless advised otherwise by a healthcare provider. Patients who have difficulty swallowing may be instructed to dissolve the tablet in water before consumption. The prepared solution should be consumed immediately to ensure the correct dose is administered. For maximum effectiveness, the medicine should be taken at the same time every day. Maintaining a consistent schedule helps keep stable medication levels in the body and supports optimal treatment results. If a dose is missed, patients should follow their physician’s recommendations. Double doses should never be taken to make up for a missed dose. Because treatment often continues for months or years, regular medical follow-ups are necessary to monitor treatment response and overall health.
Storage details: Imat 400 mg should be stored at room temperature, preferably below 30°C, in a dry place away from direct sunlight, heat, and moisture. Keep the tablets in their original packaging until use to protect them from environmental exposure. Do not store the medicine in bathrooms or near sinks, where humidity is high. Ensure that the medication is kept out of the reach of children and pets. Dispose of expired or unused tablets responsibly in accordance with local pharmaceutical disposal guidelines.
What is Imat 400mg Tablet used for?
This higher-strength tablet contains the same active ingredient, Imatinib, and is prescribed for chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST), often at standard maintenance doses.
How is the Imat 400mg dose different from the Imat 100mg tablet?
The Imat 400mg strength allows patients on a stable, higher daily dose to take fewer tablets. Your oncologist determines which strength and combination is appropriate for your treatment plan.
How should Imat 400mg be taken?
Typically once daily with a meal and a full glass of water, at the same time each day, exactly as your doctor prescribes.
What are the common side effects of imat 400mg?
Similar to the 100mg strength: nausea, swelling, muscle cramps, skin rash, diarrhea, and fatigue. Higher doses may carry a somewhat higher chance of side effects, so regular monitoring is important.
What precautions should patients follow?
Routine blood counts and liver function tests are typically required throughout treatment. Avoid grapefruit products and check with your doctor before taking any new medication, supplement, or herbal product.
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