Irovel 150mg
Available Dosages
| SKU | 544 |
|---|---|
| Generic For | Avapro |
| Strength | 150mg |
| Active Ingredient | Irbesartan |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.39 | US$ 11.84 | |||
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| 60 Tablet/s | US$ 0.39 | US$ 23.70 | |||
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| 90 Tablet/s | US$ 0.39 | US$ 35.54 | |||
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Irovel 150mg (Irbesartan) – Affordable Avapro Alternative
Irovel 150 mg tablets contains the active ingredient Irbesartan, an angiotensin receptor II antagonist used primarily for the treatment of hypertension (high blood pressure). As an angiotensin II receptor, the medicine prevents the blood vessels from narrowing, which improves the flow of blood and lowers blood pressure. Irbesartan may also be used in combination with other blood pressure medicines.
What is Irovel 150 mg used for?
Irovel 150 mg tablets are used for the treatment of hypertension. The medicine may also delay progression of diabetic neuropathy and is also used to reduce renal disease progression in patients with hypertension, type 2 diabetes, and proteinuria.
How does Irovel 150 mg work?
Irovel 150 mg tablets contain the active ingredient Irbesartan, which works by:
- Decreasing the body’s production of substances that can increase the blood pressure level
- Making the blood vessels relax and widen
- Making it easier for the heart to pump blood to all parts of the body
What are the different doses of Irovel?
Irovel tablets are available to buy online from premiumrxdrugs.com in doses of 150 mg and 300 mg. Buy Irovel 150 mg online far cheaper than other local pharmacies.
What does Irovel 150 mg contain?
Irovel 150 mg tablets contain the active ingredient Irbesartan, which belongs to a group of medicines known as angiotensin-II receptor antagonists. Each Irovel tablet contains 150 mg Irbesartan.
What are the medications interact with Irovel 150 mg?
Please tell your physician, if you are consuming any other medicines, including medicines obtained without a prescription. Your physician or pharmacist may wish to alter your dose, if you are taking any of the following drugs.
- Drospirenone
- Lithium
- Aspirin
- Enalapril
- Aliskiren
- Naproxen
- Lithium
- Ramipril
These drugs may be affected by Irovel or may affect how well Irovel works. You may need a different amount of medicines, or you may need to consume different medicines. Your physician has more information on drugs to be careful with or avoid while taking Irovel.
When should Irovel 150 mg not be used?
- You should not use Irovel 150 mg if you are allergic or have hypersensitivity to Irbesartan or to any of the other ingredients of Irovel.
- It should not be administered in children and adolescents because the efficacy and safety have not been fully established.
- Also, it should not be given to pregnant and breastfeeding women.
What are the side effects of Irovel 150 mg?
Tell your physician, if you do not feel well while consuming Irovel tablets.
All drugs can have undesired side effects. Sometimes they are severe, most of the time they are not. You may require medical help if you get some of the side effects. Inform your physician, if you notice any of the following and they worry you.
- Nausea
- Headache
- Dry mouth
- Vomiting
- Weakness
These are the most common side effects of Irovel.
Tell your physician immediately, if you experience:
- Chills
- Swelling
- Fever
- Flu symptoms
- Pain in the chest
- Pale or yellowing skin
- Rapid weight gain
- Appearance of rashes on the skin
- Bradycardia
- Sleeping problems
- Hyperkalemia
- Breathing problems
- Tachycardia
- Palpitations
- Hyperkalemia
- Anxiety disorder
- Itching
The list of the side effects listed above is not complete. If you suffer from any of these or any other unwanted effects, please inform your physician.
How should Irovel be taken?
- Irovel 150 mg tablet is for oral use. Swallow the tablet with a glass full of water. You can take it with or after consuming food.
- Irovel helps control your problem only if taken on a regular basis; therefore you must take it daily. Take the medicine regularly to get the best results.
- Do not change the dosing schedule, unless your physician advices you to do so.
- You should only take the number of tablets that you have been told. Visit your nearest medical centre immediately, if you think that you have taken too much Irovel tablets by mistake. The symptoms of an overdose include: vomiting, diarrhea, nausea, dizziness, rashes, shakiness, fatigue, and fast heart rate, etc.
How long should you take Irovel 150 mg?
Continue taking Irovel 150 mg tablets for as long as your physician recommends you.
Missed dose of Irovel 150 mg
In case, you forget to take the dose and if it is less than 2-4 hours left for the next dose, leave the missed one and take the next dose at the recommended time. Do not double up the dose for the missed one.
How should Irovel 150 mg be stored?
- Keep it out of the reach of children and away from pets. Avoid exposure to light, moisture, and heat.
- Do not place your tablets in the bathroom or near a sink.
- Do not take any medicine after the expiry date, which is mentioned on the carton.
- Always keep the medicine in the original package.
What is Irovel 150mg irbesartan used for?
Irovel 150mg contains irbesartan, an angiotensin II receptor blocker (ARB) used for high blood pressure (hypertension), kidney protection in type 2 diabetics with hypertension and microalbuminuria (early diabetic nephropathy), and as an alternative to ACE inhibitors in patients who cannot tolerate ACE inhibitor-associated cough or angioedema. The 150mg dose is typically the starting dose for hypertension management, with titration to 300mg for patients requiring stronger blood pressure control. Irbesartan is among the most potent ARBs for nephroprotection, with landmark IRMA-2 and IDNT trials demonstrating its specific kidney-protective benefits in type 2 diabetics.
How does irbesartan (Irovel 150mg) lower blood pressure?
Irovel 150mg works by selectively blocking angiotensin II type 1 (AT1) receptors throughout the vascular system. Angiotensin II is a potent vasoconstrictor that also promotes Sodiumium retention and stimulates aldosterone secretion—all effects that raise blood pressure. By blocking the AT1 receptor, irbesartan prevents angiotensin II from exerting these effects, causing vascular relaxation and reduced Sodiumium and water retention, lowering blood pressure. Unlike ACE inhibitors, ARBs like irbesartan block the final step in the RAAS cascade and do not affect bradykinin metabolism, which is why ARBs do not cause ACE inhibitor-type cough.
What is the difference between Irovel 150mg and Irovel 300mg?
Both Irovel 150mg and Irovel 300mg contain irbesartan—the difference is dose. Irovel 150mg is the standard starting dose for hypertension, providing substantial blood pressure reduction. Irovel 300mg delivers the maximum approved irbesartan dose, offering greater blood pressure reduction (additional 5–8 mmHg systolic) and stronger nephroprotection in diabetics. The IDNT trial used 300mg irbesartan for nephroprotection in type 2 diabetic nephropathy. If 150mg does not achieve blood pressure targets or adequate renal protection after 4–6 weeks, dose escalation to 300mg is typically recommended. Most patients ultimately benefit from the 300mg dose for maximum therapeutic effect.
Does Irovel 150mg cause a cough unlike ACE inhibitors?
No—this is one of the key clinical advantages of Irovel 150mg (irbesartan) and all ARBs over ACE inhibitors. ACE inhibitor cough is caused by bradykinin accumulation (a byproduct of ACE inhibition); ARBs block the angiotensin receptor directly without affecting ACE, so bradykinin levels remain unchanged and cough does not occur as a side effect. Studies show less than 1% of ARB users report a cough attributable to the drug—comparable to placebo. Irovel 150mg is frequently prescribed as a cough-free alternative for patients who were switched from ACE inhibitors due to intolerable cough.
Is Irovel 150mg safe for patients with diabetic kidney disease?
Yes, irbesartan is specifically indicated and evidence-based for nephroprotection in type 2 diabetics with hypertension and early-to-moderate diabetic nephropathy. The IRMA-2 trial demonstrated irbesartan 150mg and 300mg significantly reduced progression from microalbuminuria to overt proteinuria. The IDNT trial showed 300mg irbesartan reduced the risk of doubling serum creatinine and end-stage renal disease. ARBs reduce intraglomerular pressure and proteinuria through RAAS blockade. Irovel 150mg is a starting dose for this indication, with most patients requiring titration to 300mg for maximum nephroprotection. Regular monitoring of ACR, creatinine, and potassium is essential.
What are the side effects of Irovel 150mg irbesartan?
Irbesartan is generally very well tolerated—this is a significant advantage of ARBs. The most common notable side effect is hyperkalemia (elevated potassium), which is more likely in patients with kidney disease, those on potassium-sparing diuretics, or those taking spironolactone. Dizziness and first-dose hypotension can occur. Diarrhea, dyspepsia, and fatigue are occasionally reported. Rare but serious side effects include angioedema (much less common than with ACE inhibitors) and acute kidney injury. Unlike ACE inhibitors, irbesartan does not cause cough. Overall, ARBs have one of the best tolerability profiles among antihypertensive drug classes.
Can Irovel 150mg be combined with Amlopres (amlodipine) for blood pressure?
Yes, combining irbesartan (Irovel 150mg/300mg) with amlodipine (Amlopres 5mg/10mg) is a highly effective and recommended antihypertensive combination. Each drug lowers blood pressure through complementary mechanisms—irbesartan through RAAS blockade, amlodipine through arterial smooth muscle relaxation via calcium channel blockade. Together, they provide additive blood pressure reduction superior to either drug alone. This combination is particularly beneficial in patients with hypertension plus diabetes or kidney disease, where dual protection is needed. Fixed-dose combination products of irbesartan and amlodipine are available in some markets; otherwise, the drugs can be taken separately.
How long does it take Irovel 150mg to lower blood pressure?
Irovel 150mg begins to lower blood pressure within 1–2 hours of the first dose, with peak blood pressure reduction occurring at 3–6 hours. However, full steady-state antihypertensive effect develops over 1–2 weeks of consistent daily dosing as the RAAS is progressively suppressed. Blood pressure should be reassessed 4–6 weeks after starting Irovel 150mg to determine whether dose escalation to 300mg is needed. Irbesartan has a long half-life of 11–15 hours, enabling effective once-daily dosing with good 24-hour blood pressure coverage. Take at the same time each day for consistent effect.
Is Irovel 150mg safe with heart failure medications?
Irbesartan can be used in heart failure when ACE inhibitors are not tolerated, though ACE inhibitors remain the first-line RAAS agent for heart failure with reduced ejection fraction based on stronger trial evidence. Combining an ARB with an ACE inhibitor (dual RAAS blockade) is generally discouraged in heart failure due to increased side effects (hypotension, hyperkalemia, renal impairment) without additional mortality benefit (Val-HeFT, CHARM-Added trials showed modest benefit at cost of more adverse events). Irovel 150mg can be combined with beta-blockers and diuretics in heart failure management under cardiologist supervision.
What should I avoid while taking Irovel 150mg?
Avoid potassium supplements and salt substitutes containing potassium chloride—ARBs raise potassium levels and additional potassium increases hyperkalemia risk. NSAIDs (ibuprofen, naproxen, diclofenac) reduce irbesartan's antihypertensive effect and can worsen kidney function. Avoid dual RAAS blockade (combining irbesartan with an ACE inhibitor or aliskiren) due to increased adverse effects. Lithium levels may increase with ARBs—monitoring is needed if used together. Irbesartan is absolutely contraindicated in pregnancy—women of childbearing age must use effective contraception and stop irbesartan immediately if pregnancy occurs.
Can I buy Irovel 150mg online without a prescription?
Irbesartan (Irovel 150mg) is a prescription-only medication in the USA, UK, Australia, and most countries due to its cardiovascular and renal effects requiring medical supervision. A licensed physician must evaluate your blood pressure, kidney function, electrolytes, and medications before prescribing. PremiumRxDrugs.com requires a valid prescription for all irbesartan orders to ensure safe, appropriate use under medical oversight. Your doctor will monitor blood pressure response, kidney function, and potassium at regular intervals during therapy.
Why buy Irovel 150mg from PremiumRxDrugs.com?
PremiumRxDrugs.com offers genuine Irovel 150mg irbesartan at prices substantially lower than branded Avapro (US) or Aprovel (Europe) at Western pharmacies. The product is manufactured by reputable Indian pharmaceutical companies to international quality standards. Discreet, tracked international shipping delivers to the USA, UK, Australia, and many other countries. Customer support helps with prescription documentation, delivery timelines, and product queries. For patients managing hypertension, diabetic nephropathy, or seeking a cough-free ACE inhibitor alternative, PremiumRxDrugs.com provides trusted, affordable irbesartan.
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