Sitagliptin Metformin 50/1000mg Tablet
Istamet 50+1000mg is prescribed to lower blood sugar levels in patients with type 2-diabetes. It can be recommended alone or in combination with insulin, or sulfonylurea medicines such as gliclazide, glibenclamide, and glimepiride. This medicine is indicated as an adjunct to diet and exercise for improving glycemic control in type-2 patients. In addition to diet and exercise, this medicine is recommended when the use of the two main active ingredients Metformin or Sitagliptin alone does not adequately control the blood sugar.
What is Istamet tablet used for?
Istamet 50/1000mg drug is meant to help control blood glucose levels (type-2 diabetes). It’s used for the patients who either have not achieved good control with metformin or sitagliptin alone or who take both of these. This medicine can be used alone or in combination with insulin, or sulfonylurea medicines such as gliclazide, glibenclamide, and glimepiride.
How does Istamet pill work?
All the active ingredients of Istamet pills work in combination to control blood sugar through multiple mechanisms. Sitagliptin phosphate is a member of a class of oral anti-hyperglycemic agents (dipeptidyl peptidase 4 (DPP-4) inhibitors) which can improve glycemic control in the patients with type-2 diabetes by enhancing the levels of active incretin hormones. Sitagliptin can block a certain enzyme, which in turn helps increase the pancreas’s production and encourage the secretion of insulin while blocking the liver’s production of glucose. On the other hand, metformin makes the body’s cells more sensitive to insulin and also lowers the liver’s production of glucose and that your stomach/intestines absorb.
Where to buy Istamet pill online?
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What does Istamet contain?
Istamet 50+1000mg has Sitagliptin and Metformin, making it an effective combination to treat type-2 diabetes. Sitagliptin is available in the strength of 50 mg while 1000 refers to 1000 mg of metformin.
What are the side effects of Istamet tablet?
Much like other prescription medicines, Istamet pill may also cause some side effects. Usually, these side effects are mild and do not render any severe impact on the health of the patient. Some probable side effects of this medicine include:
- Muscle pain
- Trouble breathing
- Unusual sleepiness
- Sudden stomach or intestinal problems
- Nausea and vomiting or diarrhea
- Dizzy or lightheaded
- Irregular heartbeat
The allergic reactions of Istamet 50/1000mg may cause rash, hives, and swelling of the face, lips, tongue, and throat breathing or swallowing. Pancreatitis (inflammation of the pancreas) is another side effect that may lead to some serious consequences.
If you experience an allergic reaction, stop taking Istamet and contact your doctor right away for advice.
What medications interact with Istamet tablet?
The administration of Sitagliptin and Metformin with a sulfonylurea or with insulin may invoke an adverse reaction of hypoglycemia. Lab tests also show some minimal interactions of Istamet with the ingredients that include Sitagliptin and Metformin hydrochloride. Such drug interactions may cause hypersensitivity reactions like anaphylaxis, cutaneous vasculitis, exfoliative skin conditions, angioedema, rash, and urticaria.
When should Istamet not be taken?
People living with a kidney or liver disease should not take Istamet. Like metformin alone, Istamet tablet may raise the risk of lactic acidosis, a condition in which lactic acid builds up in the blood, depriving the body’s tissues of oxygen. If you are highly alcoholic then you should avoid this medicine, as it is more likely to cause kidney disease and heart failure.
How should Istamet be taken?
The initial dose of Istamet pill is based on the patient's current regimen. Its dosage can be adjusted based on effectiveness and tolerability while not exceeding the maximum recommended daily dose of 100mg Sitagliptin and 2000 mg Metformin extended-release. Usually, the medicine is taken once a day, preferably in the evening.
Missed dose of Istamet?
If you miss a dose of Istamet 1000mg, take it as soon as you remember. If you have forgotten until it is time for your next dose, then skip the missed dose and go back to your regular schedule.
How Istamet should be stored?
You can store this drug at room temperature, so your room temperature is good for the purpose.