SKU	598
Generic For	Levaquin
Strength	750mg
Active Ingredient	Levofloxacin

Product Description

Levoflox 750mg (Levofloxacin) – Affordable Levaquin Alternative

Levoflox 750 mg tablets comprise of the active ingredient Levofloxacin, which treats bacterial infections in many parts of the body like the sinuses, skin, lungs, ears, airways, bones, and joints. It is also used to prevent an anthrax infection after a person has been ill with anthrax. This medicine is useful in the treatment and prevention of plague (including pneumonic and septicemic plaque). Levofloxacin belongs to the class of medicines known as quinolone antibiotics which works by killing or preventing bacterial growth. The main therapeutic ingredient has a broad antibacterial activity against a range of Gram-positive bacteria, Gram-negative bacteria and, atypical organisms. The drug is effective against a wide range of infections caused by those strains of S. pneumoniae bacteria which are either susceptible or resistant to penicillin (antibiotic). It is a well-accepted drug, and has very less adverse effects on the heart or liver, which are commonly exhibited by some other broad-spectrum antibiotic drugs.

What is Levoflox 750 mg used for?

Levofloxacin, the active ingredient of Levoflox, falls into the class of drugs called quinolone antibiotics. It works by ending or preventing the growth of bacteria. Levofloxacin is used to fight bacterial infections of the skin, sinuses, kidneys, joints, bladder, or prostate. It is also useful in the treatment of bacterial infections that cause bronchitis or pneumonia, and people who have gone through anthrax or plague.

This medication is not meant for treating viral infections (such as flu, common cold). Do not use it unnecessarily or without prescription of a doctor as misuse of any antibiotic can make it less effective.

How does Levoflox 750 work?

Levofloxacin, the active constituent of Levoflox 750mg, is an antibiotic agent. It is active against both Gram-positive and Gram-negative bacteria. It kills the bacteria by interfering with their replication process. Thus, levoflox acts as a bactericide.

What does Levoflox 750 contain?

Levoflox 750 is mainly composed of Levofloxacin which is an antibiotic agent. It is reserved for infections which have not improved with other antibiotic treatment. Each tablet contains 750 mg of levofloxacin.

Precautions

What medications interact with Levoflox 750?

Inform your doctor and pharmacist about all the products you use including prescription/non-prescription drugs and herbal products. Some drugs that may interact with Levoflox are:

live bacterial vaccines ( eg: typhoid, BCG)
NSAIDs or NonSteroidal Non-Inflammatory Drugs (eg: ibuprofen, naproxen)

Some antibiotics (such as Rifampin, rifabutin) can decrease the effectiveness of birth control pills. This could cause pregnancy. If you take hormonal birth control, ask your doctor for more details.

Do not take medications containing ofloxacin along with Levofloxacin as it is very similar to ofloxacin.

This drug may interfere with certain laboratory tests (eg: urine screening for opiates), and may give false results. Make sure your laboratory personnel and doctor know that you’re using this drug.

When should Levoflox 750 not be used?

Patients who are children, pregnant, breastfeeding, allergic to quinolone antibiotics, or who have epilepsy, myasthenia gravis, heart condition or tendonitis should not use Levoflox 750.

Dosage Instructions

How should Levoflox 750 be used?

Levoflox 750 mg tablets are taken by mouth as directed by the doctor. Drink plenty of fluids while taking this medicine unless otherwise advised by your doctor.

It is always recommended to check with your health care provider before using Levoflox 750 as the dosage of the drug may vary from person to person and condition to condition.

Missed dose of Levoflox 750?

In case you miss a dose of Levoflox 750, take it as soon as you remember. However, if it’s almost time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not compensate for the missed dose.

How should Levoflox 750 be stored?

The medicine should be stored in a closed container at room temperature. Keep it safe from moisture, direct light, and heat. Do not freeze the medication. Keep it out of the reach of children.

Side Effects

What are the side effects of Levoflox 750?

Levoflox 750 has many side effects. One of them is allergic reactions which can start even only after 1 dose. Stop taking levofloxacin and call your doctor if you have any of the following symptoms of a severe allergic reaction:

trouble in breathing or swallowing
swelling of the lips, tongue, face
throat tightness
rapid heartbeat
faint

skin rash

Levoflox can cause hepatoxicity or liver damage. Call your healthcare provider if you take levoflox and have unexplained symptoms such as:

nausea or vomiting
weakness
abdominal pain
stomach pain
fever
itching
unusual tiredness
light colored bowel movements
dark colored urine
loss of appetite
yellowing of your skin or the whites of your eyes

Effect on Central Nervous System: Consult your healthcare provider if you get any of these side effects, or other changes in mood or behaviour:

seizures
see things, hear voices, or sense things that are not there
feel restless
tremors
feel anxious or nervous
confusion
trouble sleeping
nightmares
depression
light-headedness
feel more suspicious (paranoia)
suicidal thoughts or acts
an incurable headache, with or without blurred vision

Intestine infection like Pseudomembranous colitis can be caused by many antibiotics including Levoflox. It’s symptoms include:

bloody stools
stomach cramps
fever
watery diarrhoea
diarrhoea that doesn’t go away

Changes in sensation and nerve damage (Peripheral Neuropathy): Levoflox can cause permanent damage to the nerves in hands, arms, legs or feet. It’s symptoms are as follows:

pain
burning
tingling
numbness
weakness

Serious heart rhythm changes (QT prolongation and torsades de pointes):
This condition can cause an abnormal heartbeat and can be very risky.

Other symptoms include joint problems and changes in blood sugar.

How to Use

Infographics

FAQ

What is Levoflox 750mg used for?

Levoflox 750mg is the highest-strength levofloxacin tablet, reserved for serious and complex bacterial infections requiring maximum antibiotic potency. It is used for severe community-acquired pneumonia (including Legionella pneumonia), complicated urinary tract infections and kidney infections, complicated intra-abdominal infections, nosocomial (hospital-acquired) pneumonia, and infections caused by organisms with reduced susceptibility to standard doses. At 750mg once daily, it achieves very high lung, urinary, and tissue concentrations — enabling shorter courses for some infections (e.g., 5-day high-dose course instead of 10 days at lower doses).

Who should not take Levoflox 750mg?

Levoflox 750mg carries a greater risk profile than lower doses and should not be used without careful prescribing. It is contraindicated in people allergic to levofloxacin or other fluoroquinolones. It must be avoided in those with QT prolongation, epilepsy, myasthenia gravis, significant heart or kidney disease, or a history of fluoroquinolone-related tendon damage. Elderly patients (particularly those also taking steroids) are at especially high risk of tendon rupture at this dose. It is not used in children, teenagers, or during pregnancy or breastfeeding.

What is the standard dosing for Levoflox 750mg?

The typical dose is one 750mg tablet taken once daily. For severe pneumonia, a 5-day course is often used (the higher dose allows a shorter course). For complicated UTIs, 5–7 days is typical. Your doctor will determine the precise duration based on the specific infection, its location, and your response to treatment. During longer courses or in patients with kidney disease, kidney function monitoring is usually arranged. Complete the full course even if you feel significantly better within the first few days.

Should Levoflox 750mg be taken with food?

Levoflox 750mg can be taken with or without food. A light meal alongside the tablet may help reduce nausea. The key interaction rules remain the same as for lower doses: separate antacids, iron, zinc, and calcium-containing products from levofloxacin by at least 2 hours to avoid reduced absorption. With only one daily dose to manage, the timing is relatively straightforward — take it at the same time each day, and keep the standard 2-hour separation from any interfering supplements or antacids. Maintaining good hydration (2 litres of water daily) is important.

Is Levoflox 750mg safe during pregnancy or breastfeeding?

No — Levoflox 750mg is not appropriate during pregnancy or breastfeeding. Levofloxacin at any dose is generally avoided in these circumstances, and the 750mg dose — the highest available — carries proportionally greater systemic exposure. There are always safer antibiotic alternatives for pregnant or breastfeeding women with bacterial infections. If you are pregnant and told you need antibiotics, ensure your doctor is fully aware of your pregnancy status so they can confirm a pregnancy-safe alternative is prescribed instead.

Can I drink alcohol while taking Levoflox 750mg?

Alcohol should be strictly avoided while taking Levoflox 750mg. At this high dose, the nervous system effects of levofloxacin (dizziness, headache, potential for confusion or hallucinations in susceptible individuals) are at their most pronounced — alcohol significantly worsens all of these. Given that this dose is typically used for serious infections requiring hospitalisation-level treatment, abstaining from alcohol entirely is essential for both safety and recovery. Focus on hydration, rest, and completing the full antibiotic course.

How does the 750mg dose of levofloxacin allow shorter treatment courses?

Pharmacokinetic studies have shown that higher doses of levofloxacin achieve better bacterial kill rates than lower doses — specifically, higher peak antibiotic concentrations relative to the bacteria's resistance level lead to more rapid and complete bacterial eradication. This means that a 5-day course of 750mg can achieve equivalent or superior results to a 10-day course of 500mg for certain infections. This 'high-dose, short-course' strategy improves patient convenience and adherence, potentially reduces overall antibiotic exposure, and is supported by clinical guidelines for certain infections like pneumonia and complicated UTIs.

Does Levoflox 750mg interact with other medicines?

At 750mg — the highest dose — the drug interaction risks of levofloxacin are at their most clinically significant. Key interactions include: QT-prolonging medicines (serious risk of fatal heart rhythm disturbances), warfarin (significantly enhanced anticoagulant effect — requires very close INR monitoring), diabetes medicines (severe blood sugar disturbances — both hypoglycaemia and hyperglycaemia reported at this dose), corticosteroids (dramatically increased tendon rupture risk at the highest dose combined with steroids), and NSAIDs (increased seizure risk). Always review all medications with your prescriber before this dose is started.

What are the most important precautions at the 750mg dose?

The highest levofloxacin dose requires the most diligent precautions. Complete rest from exercise and physical activity is strongly advised for the full course and for at least a week after, given the substantially elevated tendon injury risk. Comprehensive sun protection (high-SPF sunscreen and protective clothing) is important, as photosensitivity is more pronounced at higher doses. Blood sugar levels must be monitored closely if you have diabetes. Report any new or worsening neurological symptoms — confusion, agitation, difficulty thinking clearly, or unusual mood changes — to your doctor immediately. Regular kidney function monitoring is arranged during longer courses.

What should I do if I miss a dose of Levoflox 750mg?

Take the missed dose as soon as you remember on the same day. If you only notice on the following day, skip the missed dose and take the next regular daily tablet as planned — never take two 750mg tablets on the same day. Each missed dose represents a full day without antibiotic coverage, which is particularly significant at this high dose during a short 5-day course for pneumonia. Phone reminders set to the same time each day — linked to a fixed daily routine — provide the most reliable way to ensure every dose is taken as prescribed.

What are the common side effects of levofloxacin?

At the 750mg dose, the common side effects of levofloxacin are similar to those at lower doses but tend to be more noticeable. Nausea, diarrhoea, stomach discomfort, headache, and dizziness are the most frequently reported. Insomnia and vivid dreams are also common. Increased skin sensitivity to sunlight means sunburn can occur much more easily than usual. Some people experience a feeling of restlessness or generalised anxiety. Mild tendon discomfort (especially in the heel) should be reported promptly to your doctor rather than managed at home with painkillers.

What side effects of levofloxacin at the 750mg dose are medical emergencies?

The highest dose of levofloxacin carries the most serious risk of several emergencies. Sudden tendon pain, swelling, or rupture (especially the Achilles tendon) — stop the antibiotic immediately and seek care. Seizures, severe confusion, hallucinations, or sudden psychotic symptoms require emergency assessment. Heart rhythm abnormalities (palpitations, chest pain, collapse) need urgent care — risk of QT prolongation is most significant at this dose. Peripheral neuropathy (burning, tingling, or numbness in hands or feet) should be reported to your doctor without delay, as it can become permanent if the medicine is continued. Anaphylaxis requires immediate emergency care.

Levoflox 750mg