SKU	630
Generic For	Cozaar
Strength	25mg
Manufacturer	Unichem
Active Ingredient	Losartan potassium

Product Description

Losacar 25mg (Losartan potassium) – Affordable Cozaar Alternative

Losacar 25 mg is a prescription medicine indicated for the treatment of hypertension (high blood pressure) and heart failure. Reducing blood pressure levels prevents future heart attacks and strokes. This medication is also useful in preserving kidney function in patients with diabetes. The active ingredient of the medicine is Losartan potassium, which blocks the activity of certain substances in the body that cause tightening of blood vessels. Losartan helps relax and widens blood vessels, thus lowering blood pressure levels and making it easier for the heart to pump blood around the body.

Hypertension: Losacar treats hypertension to lower blood pressure. Controlling blood pressure levels reduces the risk of mild to life-threatening cardiovascular events, primarily myocardial infarction. Control of blood pressure should be a part of cardiovascular risk management, including, as appropriate, diabetes management, lipid control, limited sodium intake, smoking cessation, and antithrombotic therapy. Many people will require more than one medicine to attain blood pressure goals. Loscar may be used with other antihypertensive medicines.
Hypertensive patients with left ventricular hypertrophy: Losacar causes a reduction in the risk of stroke in patients with hypertension and left ventricular hypertrophy (when the left ventricle of the heart may not be pumping efficiently.
Nephropathy in type 2 diabetic patients: Losacar is effective in treating diabetic neuropathy with elevated proteinuria in patients with Type 2 diabetes mellitus and a history of high blood pressure. The medicine reduces the rate of progression of neuropathy in such people.

Precautions

Losacar 25 mg is contraindicated in patients who are hypersensitive to Losartan potassium or any other ingredients in this formulation. Coadministration of Aliskiren with Losartan potassium in patients with diabetes should be avoided.

Inform your healthcare professional about all the medications you take, including prescription and non-prescription medications, vitamins, and herbal supplements. Losacar and certain other medicines may interact. Especially let your healthcare provider know if you are taking potassium supplements, diuretics (water pills), salt substitutes containing potassium, pain relievers, arthritis medicines, Nonsteroidal anti-inflammatory drugs (NSAIDs), or other medicines to reduce blood pressure.

It is still not known whether this medicine is excreted in breast milk, but significant levels of the medicine were found in animal studies. Taking this antihypertensive agent during pregnancy can cause injury and even death of teh unborn baby. The medicine’s usage is contraindicated in pregnant women. If you are planning to conceive, seek a healthcare professional’s advice.

This medicine may pass into breast milk. Discuss with a healthcare expert while breastfeeding.

Dosage Instructions

Side Effects

All medicines may have unintended or unwanted effects, so-called side effects. Inform your healthcare provider right away about any unusual symptoms that bother you or become troublesome.

The common side effects associated with this medicine include fatigue, dizziness, diarrhoea, vomiting, headache, change in taste, rash, back pain, leg pain, or muscle cramps.

Some patients, especially those who are suffering from type 2 diabetes with protein in the urine, may also develop increased levels of potassium in the bloodstream. Losartan potassium can cause abnormal blood test results. Your healthcare specialist will decide when to conduct blood tests and will provide the results.

Serious side effects may also happen with the use of Losacar. These serious side effects include liver disorder (jaundice), decreased platelets, increased levels of potassium in the bloodstream, low blood pressure, kidney disease, and rhabdomyolysis. If any of these adverse effects affect you severely, seek immediate medical attention.

How to Use

Hypertension: The usual starting dose is Losacar 50 mg once a day. The dosage may be increased to a maximum dose of 100 mg once a day as required to gain control over blood pressure.
Hypertensive patients with left ventricular hypertrophy: The recommended starting dose is 50 mg once a day. A thiazide medicine such as hydrochlorothiazide 12.5 mg daily should be added. The dose of Losacar should be increased to 100 mcg once a day, followed by an increase in hydrochlorothiazide to 25 mg once a day based on the blood pressure response of a patient.
Nephropathy in patients with type 2 diabetes: The recommended dose is 50 mg once daily. The dose should gradually be increased to 100 mg once a day based on the patient’s blood pressure response.
Hepatic impairment: The suggested starting dose is 25 mg in patients suffering from mild to moderate hepatic insufficiency.

Infographics

FAQ

What is losartan 25 mg prescribed for?

Losartan 25 mg is the starting dose of this angiotensin receptor blocker (ARB), used to initiate hypertension treatment while minimising the risk of excessive blood pressure lowering. Losacar 25mg — generic Cozaar — is particularly useful for initiating therapy in elderly patients, those with volume depletion, or patients transitioning from an ACE inhibitor. It is also the starting dose for diabetic nephropathy in some protocols. The 25 mg dose can be increased as tolerated.

How does losartan 25 mg work to reduce blood pressure?

Losartan selectively blocks angiotensin II at the AT1 receptor subtype, preventing angiotensin II from causing blood vessel constriction and aldosterone release. The 25 mg dose provides partial AT1 receptor occupancy, delivering a gentle blood pressure reduction suitable for initiation in sensitive patients. As the dose is increased toward 50–100 mg, more complete receptor blockade is achieved, with proportionally greater blood pressure reductions.

When is the right time to take Losacar 25mg daily?

Losacar 25mg is taken once daily at a consistent time — morning or evening, with or without food. The most important factor is regularity. Starting in the morning allows your doctor to monitor blood pressure effects during your waking hours. As the body adjusts over the first 1–2 weeks, any initial dizziness associated with the first few doses typically resolves. Taking it with a glass of water after breakfast is a common approach to build the habit.

How quickly does losartan 25 mg begin to reduce blood pressure?

Losartan 25 mg begins acting within 1–6 hours of the first dose, with a mild but measurable blood pressure reduction. Consistent therapeutic control develops over 1–3 weeks. Because this is a starting dose, the full antihypertensive benefit may not be apparent until the dose is titrated upward to 50 mg or 100 mg. Blood pressure monitoring at home helps guide your prescriber's decision about when and how much to increase the dose.

Is losartan 25 mg safe for patients who previously had cough on ACE inhibitors?

Yes — losartan is an ARB, not an ACE inhibitor, and does not cause the dry, persistent cough associated with ACE inhibitor use. ACE inhibitor cough occurs due to bradykinin accumulation, which is not affected by losartan's mechanism. Losartan 25mg is a standard switching option for patients who need renin-angiotensin system blockade but cannot tolerate ACE inhibitor cough. The 25 mg starting dose is appropriate when beginning ARB therapy post-ACE inhibitor switch.

Can losartan 25 mg cause dizziness in the first week?

Yes, particularly during the first few doses, losartan 25mg can cause mild dizziness — especially when standing up quickly (orthostatic hypotension). This is more pronounced in patients who are already on diuretics or have a low-Sodiumium diet. Starting at the lowest dose (25 mg) and monitoring blood pressure in the first week allows this effect to be identified and managed before escalating to higher doses. The dizziness typically diminishes as the body adjusts.

How does Losacar 25mg compare to valsartan 40mg as a starting ARB dose?

Losacar 25mg (losartan) and valsartan 40mg are both starting doses of ARBs for hypertension. Valsartan at 40mg tends to have a slightly shorter duration of action, while losartan 25mg provides consistent 24-hour coverage even at this introductory dose. Both are well-tolerated starting options. Losartan's unique uric acid-lowering property gives it a practical advantage for patients with gout or high uric acid levels.

Is Losacar 25mg equivalent to Cozaar 25mg?

Yes. Losacar 25mg is a generic equivalent of Cozaar 25mg, containing losartan potassium 25 mg manufactured to bioequivalence standards. Both deliver the same degree of angiotensin II receptor blockade and blood pressure control. For patients initiating therapy or using losartan 25mg as a long-term maintenance dose (e.g., in elderly patients), Losacar provides the same outcomes as Cozaar at a significantly lower cost.

Can I buy Losacar 25mg online from a reputable pharmacy?

Yes. PremiumRxDrugs.com stocks Losacar 25mg and ships to the USA, UK, Australia, and worldwide. The licensed pharmacy has supplied authentic, manufacturer-sourced cardiovascular medicines for over a decade. Competitive pricing, discreet packaging, free shipping on qualifying orders, and easy prescription submission make PremiumRxDrugs.com a trusted source for patients starting losartan therapy.

Can I order losartan 25 mg online and get it shipped to the UK or Australia?

Yes. PremiumRxDrugs.com ships losartan 25mg — including Losacar — to the UK, Australia, USA, and many other countries. Patients benefit from authentic manufacturer-sourced medicine at competitive prices, discreet packaging, and free worldwide shipping on qualifying orders. The prescription management system makes reordering straightforward, ensuring uninterrupted access to your blood pressure medication no matter where you are.

What side effects are associated with losartan 25 mg?

Losartan 25 mg is one of the best-tolerated antihypertensive doses. Side effects at this starting dose include mild dizziness, back pain, and fatigue. Elevated potassium is a concern in patients with kidney disease or those taking potassium supplements. Because losartan blocks the renin-angiotensin system, a mild initial drop in kidney function tests (creatinine and eGFR) is sometimes seen — this is expected and should stabilise unless the rise is significant.

What precautions apply to losartan 25 mg treatment?

Losartan 25 mg should not be taken in pregnancy from the second trimester. Patients with bilateral renal artery stenosis, single functioning kidney, or hyperkalemia should be monitored carefully. NSAIDs can reduce losartan's effectiveness and increase kidney injury risk. Inform your doctor if you are on any potassium-sparing diuretics, as this combination raises hyperkalaemia risk. Blood pressure and kidney function tests are recommended 2–4 weeks after starting therapy.

Losacar 25mg