Mesacol CR 500 mg
| SKU | 2626 |
|---|---|
| Generic For | Canasa |
| Manufacturer | Sun Pharmaceuticals Ltd |
| Active Ingredient | Mesalazine Prolonged Release |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 1.00 | US$ 30.00 | |||
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| 60 Tablet/s | US$ 0.90 | US$ 54.0010%US$ 60.00 | |||
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| 90 Tablet/s | US$ 0.85 | US$ 76.5015%US$ 90.00 | |||
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Mesacol CR 500mg – Affordable Canasa Alternative
Mesacol CR 500mg is an anti-inflammatory medicine that is recommended to diagnose a certain type of bowel disease known as ulcerative colitis and Crohn's disease. Mesalazine (also known as mesalamine or 5-Aminosalicylic acid) is the main active ingredient of the Mesacol CR tablet that can effectively treat ulcerative colitis (an inflammatory condition that causes ulcers in the linings of your large intestines). This medicine is also useful to prevent the symptoms of internal inflammation, as it can reduce swelling and pain. Mesacol CR 500mg is not recommended for children below 6 years old, and it should not be taken without a medical prescription.
Benefits of Mesacol CR 500mg
Mesalazine, the active component of Mesacol, helps you to deal with symptoms like diarrhea, bleeding, and stomach pain by reducing inflammation in the bowel. This anti-inflammatory drug has a controlled-release formulation of mesalamine that helps you treat stomach ulcers and internal inflammation.
The working mechanism of the Mesacol CR 500mg tablet
Mesacol CR 500mg medicine is an aminosalicylate, which belongs to the class of medications primarily used to diagnose inflammatory bowel diseases (IBDs) such as ulcerative colitis and Crohn's disease or Crohn's ileocolitis. Mesalazine reduces the production of chemical messengers (prostaglandins) that cause inflammation (swelling) in the intestines. This process can reduce the risk of inflammation in the colon's lining. In other words, Mesacol CR tablet works by targeting prostaglandins, which are inflammatory compounds, to treat stomach ulcers. It works in the gut and is formulated to release the medication gradually through the gastrointestinal tract, reducing the intensity of inflammation.
Do not take Mesacol CR 500mg tablet if you are allergic to Mesalamine, salicylates (such as acetylsalicylic acid), sulphasalazine or any other substances of this drug. Patients living with serious kidney/liver disease should discuss their medical history with their doctor before taking this medicine. Moreover, if you have lung problems, narrowing/blockage of the stomach/gut, and/or mild to moderate kidney/liver problems, it is advised to consult a doctor for a medical prescription.
Mesacol CR 500mg tablet is not recommended for adolescents or teenagers, and people above 65 years have to consult a doctor before starting medication. Usually, it is not recommended during pregnancy or breastfeeding without a doctor's approval. People allergic to salicylates (like aspirin) have to be cautious as well.
This medicine could cause some mild and temporary side effects that do not require any medical attention, and they disappear after some days of medication. Some common side effects of the Mesacol tablet include:
- Stomach pain/epigastric pain
- Abdominal pain
- Flatulence
- Headache
- Rash
- Vomiting
- Diarrhea
- Nausea
The rare but serious side effects of Mesacol CR 500mg are pancreatitis, kidney issues (nephrotoxicity), and blood disorders. If you experience any disturbance in the respiratory system or kidney function, go for a medical test, as this medication course may last a long.
You can swallow Mesacol CR 500mg tablet as a whole with a little amount of water before or after a meal. It is advised to take this medicine at a fixed time every day for better results. It is important to follow the medication instructions provided by the doctor to get the maximum benefits of the medicine. If you have any specific questions or concerns regarding your medication, you should discuss those with a doctor for the safe administration of any medicine.
What is Mesalazine Prolonged Release and what condition does it treat?
Mesalazine Prolonged Release is an anti-inflammatory medication primarily used to treat ulcerative colitis, a chronic inflammatory bowel disease affecting the colon and rectum. Available under brand names like Mesacol CR 500mg, this aminosalicylate medicine helps reduce inflammation in the intestinal lining, managing symptoms such as abdominal pain, diarrhoea, and rectal bleeding. The prolonged-release formulation ensures the active ingredient mesalazine is released slowly throughout the digestive tract, targeting inflamed areas effectively. This IBD medication is also prescribed for maintaining remission in Crohn's disease in some cases, helping patients manage their condition long-term.
How does Mesalazine Prolonged Release work in the body?
Mesalazine Prolonged Release works locally in the gastrointestinal tract by inhibiting the production of inflammatory chemicals called prostaglandins and leukotrienes. This aminosalicylate drug acts directly on the inflamed intestinal tissue, reducing swelling, irritation, and ulceration in ulcerative colitis patients. The controlled-release technology in formulations like Mesacol CR 500mg ensures the active ingredient mesalazine reaches the colon intact, where it's needed most. Unlike systemic medications, this IBD treatment primarily works at the site of inflammation rather than throughout the entire body, which contributes to its favourable safety profile for long-term inflammatory bowel disease management.
How long does Mesacol CR 500mg take to work?
Mesacol CR 500mg typically begins providing symptom relief within three to fourteen days of starting treatment, though individual response times vary. Some ulcerative colitis patients notice improvements in diarrhoea and abdominal discomfort within the first week, while complete remission may require four to eight weeks of continuous use. The prolonged-release formulation of mesalazine works gradually, allowing sustained anti-inflammatory action throughout the digestive system. For maintenance therapy, this IBD medication continues working preventatively to keep inflammation under control. Maximum therapeutic benefits usually develop after consistent daily use for at least one month, making patience and adherence essential for optimal bowel disease management.
When and how should I take Mesacol CR 500mg?
Take Mesacol CR 500mg exactly as prescribed, usually two to three times daily with or after meals to minimize stomach upset. Swallow the prolonged-release tablets whole with water—never crush, chew, or break them, as this destroys the controlled-release mechanism that delivers mesalazine to your colon. Maintaining a consistent schedule helps optimize this aminosalicylate medication's effectiveness for ulcerative colitis management. Space doses evenly throughout the day for steady anti-inflammatory coverage. If you miss a dose, take it when remembered unless it's nearly time for your next scheduled tablet. Always follow your doctor's specific instructions regarding dosage and timing.
Is Mesacol CR 500mg safe for long-term use?
Yes, Mesacol CR 500mg is generally considered safe for long-term use in managing chronic ulcerative colitis and maintaining remission. This mesalazine-based aminosalicylate has been prescribed for extended periods—often years—with a well-established safety profile for inflammatory bowel disease patients. The prolonged-release formulation allows continuous anti-inflammatory protection while minimizing systemic exposure. Regular monitoring through blood tests and kidney function assessments helps ensure ongoing safety during extended therapy. Most patients tolerate this IBD medication well over time, experiencing significantly fewer side effects compared to systemic immunosuppressants or corticosteroids used for similar gastrointestinal conditions, making it a preferred maintenance treatment option.
Can I take Mesacol CR 500mg with other medicines?
Mesacol CR 500mg can generally be taken alongside most medications, but certain drug interactions require caution. This mesalazine medication may interact with azathioprine or mercaptopurine, potentially increasing blood disorder risks. Antacids and proton pump inhibitors might affect the prolonged-release coating, altering how the aminosalicylate reaches your intestines. NSAIDs like ibuprofen may worsen ulcerative colitis symptoms when combined with this IBD treatment. Lactulose and similar laxatives can change intestinal pH, potentially affecting mesalazine absorption. Always inform healthcare providers and pharmacists about all medications, supplements, and herbal products you're taking to avoid problematic combinations with your bowel disease therapy.
How does Mesacol CR 500mg compare to similar medicines in its class?
Mesacol CR 500mg belongs to the aminosalicylate class of inflammatory bowel disease medications, which includes alternatives like Asacol, Pentasa, and Salofalk. The key differentiator is its prolonged-release technology, which delivers mesalazine specifically to the colon where ulcerative colitis inflammation occurs. Compared to immediate-release formulations, this controlled-release version requires fewer daily doses while maintaining consistent therapeutic levels. Unlike sulphasalazine, another aminosalicylate, mesalazine-based products like Mesacol CR cause fewer allergic reactions and side effects. The 500mg strength offers flexible dosing for both active disease treatment and maintenance therapy, making it a versatile option within the 5-ASA medication category for gastrointestinal conditions.
Is the generic Mesalazine Prolonged Release as effective as branded versions?
Generic Mesalazine Prolonged Release formulations are equally effective as branded versions like Mesacol CR 500mg when manufactured to pharmaceutical standards. All contain the same active ingredient in identical concentrations and use controlled-release technology to deliver the aminosalicylate to inflamed intestinal tissue. Regulatory agencies in the USA, UK, Australia, and Canada require generic IBD medications to demonstrate bioequivalence to their branded counterparts, ensuring comparable therapeutic outcomes for ulcerative colitis patients. The primary difference lies in cost rather than clinical effectiveness. Many gastroenterologists prescribe generic mesalazine for inflammatory bowel disease management, offering substantial savings without compromising treatment quality or symptom control.
Why do patients choose PremiumRxDrugs for Mesacol CR 500mg?
Patients choose PremiumRxDrugs for Mesacol CR 500mg because of guaranteed medication authenticity, competitive pricing, and reliable service spanning more than 10 years. As a licensed online pharmacy provides genuine mesalazine prolonged-release tablets sourced directly from manufacturers, eliminating concerns about counterfeit IBD medications. Our simplified prescription management and easy reorder system particularly benefits ulcerative colitis patients requiring ongoing aminosalicylate therapy. International customers across the USA, UK, Australia, and Canada appreciate discreet packaging and flexible shipping options, including free delivery programs. The combination of affordable pricing on both branded and generic inflammatory bowel disease treatments, responsive customer support, and consistent product quality has earned PremiumRxDrugs lasting trust from the gastrointestinal medication community.
What are the common side effects of Mesalazine Prolonged Release?
Common side effects of Mesalazine Prolonged Release include headache, nausea, abdominal pain, diarrhoea, and indigestion, affecting approximately 1 in 10 patients with ulcerative colitis. Some people experience flatulence, dizziness, or skin rashes while taking this aminosalicylate medication. These IBD treatment side effects are usually mild and often diminish as your body adjusts to the anti-inflammatory therapy. Less commonly, joint pain or back discomfort may occur. Serious reactions like severe allergic responses, unexplained bruising, persistent fever, or blood disorders are rare but require immediate medical attention. Most inflammatory bowel disease patients tolerate this medication well, with side effects significantly milder than corticosteroids or immunosuppressive alternatives.
Who should avoid taking Mesalazine Prolonged Release?
People with known hypersensitivity to Mesalazine Prolonged Release, salicylates like aspirin, or aminosalicylate medications should avoid this treatment. Patients with severe kidney or liver impairment require careful evaluation before starting this IBD therapy, as the medication is processed through these organs. Those with active peptic ulcers or blood clotting disorders need alternative inflammatory bowel disease treatments. Children under two years typically shouldn't receive this aminosalicylate without specialist guidance. Pregnant women, especially during the third trimester, and breastfeeding mothers require medical consultation before using mesalazine-based medications. Anyone with a history of severe allergic reactions to sulphasalazine or similar gastrointestinal anti-inflammatory drugs should discuss safer ulcerative colitis treatment alternatives.
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