Monotrate SR 30mg
Available Dosages
| SKU | 551 |
|---|---|
| Generic For | Isosorb Mono |
| Strength | 30mg |
| Manufacturer | Sun Pharma |
| Active Ingredient | Isosorbide Mononitrate |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.23 | US$ 6.89 | |||
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| 60 Tablet/s | US$ 0.23 | US$ 13.77 | |||
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| 90 Tablet/s | US$ 0.23 | US$ 20.66 | |||
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Monotrate SR 30mg – Affordable Isosorb Mono Alternative
Monotrate SR 30mg is an oral extended-release formulation of Isosorbide Mononitrate, the primary active metabolite of Mononitrate dinitrate. It is indicated for the prevention of angina pectoris in patients with coronary heart disease. The active component of the medicine Isorbide mononitrate, is an organic nitrate, which is known to widen blood vessels in the heart to allow an increased amount of blood to flow to ischemic regions. This medicine will not relieve chest pain once it occurs.
What is Monotrate SR 30mg used for?
Monotrate SR 30 mg has been discovered to prevent angina pectoris. It treats angina by dilating blood vessels, which make the heart to pump blood efficiently. The medicine has categorized as a nitrate, which is used to prevent an angina attack from happening; it will not stop a chest pain that has already started or in progress.
How does Monotrate SR work?
Monotrate SR 30mg comprises of an active ingredient Isosorbide mononitrate, which produces vasodilation. It works by reducing left ventricular end-diastolic volume and left ventricular end-diastolic pressure, which results in reduced myocardial oxygen consumption. It also increases coronary blood flow by dilating coronary arteries and improving the collateral flow to the regions where blood supply is restricted. In this way, the medicine provides relief and prevents angina attacks.
What does Monotrate SR contain?
Monotrate SR contains Isosorbide mononitrate as the main active ingredient. Each prolonged-release tablet delivers 30 mg of Isosorbide Mononitrate to the patient.
What medications interact with Monotrate SR?
- Co-administration of sildenafil, vardenafil, or tadalafil with Monotrate SR 30mg may cause hypotension. Therefore, drugs of men’s health category should be avoided during the treatment.
- Beta blockers, phenothiazines, antihypertensive, acute ingestion of alcohol may also add up to the risk of hypotension.
- When should Monotrate SR not be used?
- Monotrate SR 30mg should not be used in patients with known hypersensitivity to Isosorbide mononitrate or other ingredients of the formulation.
- Concurrent use of Monotrate SR with tadalafil, vardenafil, or sildenafil is contraindicated.
- It should not be used just before physical activities to prevent chest pain. Other medicines may be prescribed by your physician for these conditions. Consult your physician to get detailed information.
Effect of alcohol on Monotrate SR
Alcohol may increase the risk of hypotension in patients taking Monotrate SR 30mg. Therefore, alcohol consumption should be avoided during the treatment.
What are the side effects of Monotrate SR?
The side effects related to the usage of Monotrate SR 30mg are:
- Cardiovascular system disorders: paradoxical bradycardia, hypotension, syncope, and tachycardia.
- Central nervous system disorders: A headache and dizziness
- Gastrointestinal issues: Vomiting and nausea
- Dermatological effects: rash, abnormal hair texture, pruritus, acne, skin nodule, and increased sweating
- Respiratory system diseases: increased sputum, pulmonary infiltration, bronchitis, rhinitis, coughing, sinusitis, dyspnea, and bronchospasm
- Psychiatric issues: Insomnia, depression, confusion, anxiety, nervousness, somnolence, and impaired concentration
- Reproductive health related problems: decreased libido, impotence, breast pain, and atrophic vaginitis
- Miscellaneous: tolerance, flushing, etc.
How should Monotrate SR be used?
The recommended dose is 30 mg. It can be given as a single 30 mg tablet or half of a 60mg tablet once a day. Depending on the condition, your physician may increase your dose to 120 mg once daily. In rare cases, 240 mg may be required. The daily dose of Isosorbide mononitrate should be taken in the morning on arising. The tablets should not be crushed or chewed and should be swallowed with a glass full of water. Never break the tablet. Do not stop the treatment without consulting your physician. Always follow your physician’s instructions.
How long should you take Monotrate SR?
Monotrate SR should be used for as long as suggested by the physician. Use it regularly to get the best results.
Missed dose of Monotrate SR
If you forget or miss a dose of Monotrate SR 30mg, do not try to make it up by doubling up your dose. Leave the missed dose and go back to your usual dosing schedule as soon as you can. And, do not forget to inform your physician about the missed dose.
How should Monotrate SR be stored?
Keep the tablets in its original packet when not in use. Store it in a safe place where children and pets cannot reach it. It should be stored at room temperature. Place the medicine away from heat and moisture.
What is Monotrate SR 30mg used for?
Monotrate SR 30mg contains isosorbide mononitrate 30 mg sustained-release, a long-acting nitrate vaSodiumilator used to treat stable angina pectoris (chest pain) prevention and chronic heart failure as an adjunct. As a generic for Imdur / Ismo, it works by releasing nitric oxide in vascular smooth muscle, causing vaSodiumilation — particularly of veins — which reduces cardiac preload, myocardial oxygen demand, and angina frequency. This 30 mg sustained-release formulation is a sustained-release formulation that extends drug delivery for more convenient, once-daily angina prevention, providing reliable therapeutic control for patients requiring consistent long-term management.
How does isosorbide mononitrate in Monotrate SR 30mg work?
Isosorbide mononitrate works by releasing nitric oxide in vascular smooth muscle, causing vaSodiumilation — particularly of veins — which reduces cardiac preload, myocardial oxygen demand, and angina frequency. This pharmacological action reduces stable angina pectoris effectively, making it an established treatment option in its therapeutic class. At the 30 mg sustained-release dose, the drug achieves meaningful therapeutic blood levels within hours of administration, with sustained effects lasting throughout a once or twice-daily dosing interval.
What is the correct dosage and schedule for Monotrate SR 30mg?
Monotrate SR 30mg (isosorbide mononitrate 30 mg sustained-release) is taken as directed by your physician — typically once or twice daily at a consistent time. Swallow the tablet whole with water, with or without food. Do not adjust the dose or frequency without medical guidance. Consistent daily dosing maintains therapeutic drug levels that are essential for sustained blood pressure or cardiovascular management. If a dose is missed, take it as soon as possible unless the next dose is imminent.
How long does Monotrate SR 30mg take to control stable angina pectoris?
Most patients notice an initial therapeutic response to Monotrate SR 30mg within 1–2 weeks of consistent daily use. The full effect at the 30 mg sustained-release dose typically develops over 2–4 weeks. Cardiovascular benefits — reduced heart attack, stroke, and end-organ damage risk — accrue over months to years of sustained therapy. Blood pressure or other clinical parameter monitoring during the first month helps your doctor determine if the dose is adequate or needs adjustment.
Is Monotrate SR 30mg safe for long-term use in adults?
Monotrate SR 30mg has a well-established safety profile for long-term use when monitored appropriately. Regular blood pressure checks, periodic kidney and liver function tests, and clinical assessments are recommended. Patients with pre-existing organ impairment may require dose adjustments. The risk-benefit profile of long-term isosorbide mononitrate therapy is strongly positive for patients with stable angina pectoris (chest pain) prevention and chronic heart failure as an adjunct, given the significant cardiovascular harm of untreated disease.
Can Monotrate SR 30mg be combined with other blood pressure medications?
Monotrate SR 30mg can be used alongside complementary antihypertensives — such as diuretics or other drug classes — when monotherapy doesn't achieve blood pressure targets. However, combining multiple antihypertensives increases the risk of excessive blood pressure reduction (hypotension). Always inform your doctor and pharmacist of all medications before adding Monotrate SR 30mg to your regimen. Monitoring blood pressure regularly when starting combination therapy is advisable.
How does Monotrate SR 30mg compare to isosorbide dinitrate?
Isosorbide mononitrate (ISMN) and isosorbide dinitrate (ISDN) are both nitrates for angina prevention, but ISMN is the active metabolite — it doesn't require hepatic conversion and has more predictable bioavailability. ISMN's longer duration makes once or twice-daily dosing possible, whereas ISDN typically requires more frequent dosing. ISMN is generally preferred for maintenance angina prevention. The choice between Monotrate SR 30mg and isosorbide dinitrate (Isordil) depends on individual blood pressure response, other health conditions, drug tolerability, and cost. Both are established options; your prescribing physician is best placed to determine which suits your cardiovascular profile.
Is Monotrate SR 30mg a good generic alternative to Imdur / Ismo?
Yes. Monotrate SR 30mg contains the same active ingredient — isosorbide mononitrate — at 30 mg sustained-release, manufactured to bioequivalence standards that ensure identical pharmacokinetics and clinical outcomes to branded Imdur / Ismo. Patients switching from Imdur / Ismo to Monotrate SR 30mg can expect the same therapeutic control. The major advantage of the generic is cost — significantly more affordable for patients on indefinite long-term therapy.
Can I order Monotrate SR 30mg from PremiumRxDrugs.com with discreet delivery?
Yes. PremiumRxDrugs.com delivers Monotrate SR 30mg in discreet packaging to patients in the USA, UK, Australia, and many other countries worldwide. Our licensed pharmacy model, over a decade of trusted service, and genuine manufacturer-verified medicines — combined with competitive pricing and free shipping on qualifying orders — make us a preferred choice for patients seeking private, affordable access to long-term cardiovascular therapy.
What side effects does Monotrate SR 30mg commonly cause?
Common side effects of isosorbide mononitrate include headache (very common, especially at the start of therapy), dizziness, flushing, low blood pressure, and nausea. Most side effects are dose-related and mild, often resolving as the body adjusts over the first few weeks. Persistent, severe, or worsening symptoms should be reported to your prescriber, who can assess whether dose adjustment or an alternative medication is appropriate for your situation.
Who should not take Monotrate SR 30mg?
Monotrate SR 30mg is contraindicated in patients with severe anaemia, raised intracranial pressure, cardiogenic shock, hypovolemia, concurrent use of PDE5 inhibitors (sildenafil, tadalafil, vardenafil), and known nitrate hypersensitivity. Pregnant women should avoid this medicine, as many cardiovascular drugs carry fetal risk. Always provide your complete medical history — including all diagnosed conditions and current medications — to your prescriber before starting Monotrate SR 30mg. Regular follow-up ensures safety concerns are detected and managed proactively during long-term treatment.
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