SKU	759
Generic For	Benicar
Strength	40mg
Manufacturer	Sun Pharma Laboratories Ltd
Active Ingredient	Olmesartan

Product Description

Olvance 40mg (Olmesartan) – Affordable Benicar Alternative

Olvance 40 mg is indicated for the treatment of high blood pressure, also known as hypertension. Blood pressure helps push blood all around your body. It tends to fluctuate at different times of the day, depending on whether you are active or inactive/, or whether you are worried. You develop high blood pressure when your blood pressure stays higher than the body’s requirement, even when you are calm and relaxed. Usually, hypertension shows no symptoms. The only way to know if your blood pressure is high is to have it checked regularly. If left untreated, it can lead to serious health problems, such as heart disease, stroke and kidney failure.

The active ingredient of the medicine is Olmesartan, which belongs to a class of medications known as angiotensin-II receptor antagonists. Angiotensin II is a substance released inside the body which causes tightening of blood vessels. Olmesartan works by blocking the action of angiotensin II, which causes the relaxation of blood vessels and thereby lowers blood pressure.

Precautions

Things to consider while using Olvance 40mg tablet

Do not take Olvance 40 mg if you have serious problems with your kidneys and liver, or have diabetes. The use of olmesartan is contraindicated in patients who have experienced hypersensitivity reactions to olmesartan or any of its inactive ingredients. Symptoms of hypersensitivity reactions may include itchiness, rash, swelling of the face, lips, or tongue, muscle pain, tenderness, or joint pain. Do not take this antihypertensive agent if you are pregnant or breastfeeding. The medication may get into your uterus, or it may pass into the breast milk, and there’s a high chance that your baby may be affected. In case the pregnancy is discovered, antihypertensive treatment should be stopped immediately.

Before you start to take Olvance 40, tell your healthcare provider if you have had any medical conditions, especially liver problems, kidney disease, heart problems, high levels of potassium in your blood, excessive vomiting or diarrhoea, or problems with your adrenal glands. Some medications and Olmesartan may interfere with each other and cause side effects. These include:

Potassium supplements or potassium-containing salt substitutes
Other medicines used for the treatment of high blood pressure
Non-steroidal anti-inflammatory drugs (NSAIDs) or COX-2 inhibitors are medications used to relieve pain, swelling, and other inflammatory symptoms, including those associated with arthritis.
Other diuretics are also referred to as water tablets.
Lithium is used for the treatment of mood swings and some depressive symptoms.
Any medicines that contain aliskiren
Other medicines that may increase serum potassium

These medicines may interact with Olmesartan or affect how well it works. You may need to adjust the dosage of your medicine, or you may require a different medication. Consult your doctor. Your doctor will advise on this. If you feel lightheaded, dizzy, or faint when getting out of bed or standing up slowly, it may be a sign of a condition called orthostatic hypotension. Be careful while driving or operating machinery until you know how this antihypertensive agent affects you. If you consume alcohol, lightheadedness or dizziness may get worse.

Dosage Instructions

Side Effects

Possible side effects of Olvance 40mg

Olvance helps most people with high blood pressure, but like any other pharmaceutical agent, it may have unwanted side effects. If you are over 65 years of age, you may have increased chances of developing side effects. Inform your healthcare provider if you develop side effects such as headache, cough, feeling lightheaded, or feeling sick, nausea, vomiting, diarrhoea, stomach pain, bronchitis, unusual tiredness, running or blocked nose, back pain, urinary tract infections, sore throat and discomfort when swallowing, flu-like symptoms, an uncomfortable feeling in the stomach. These common side effects are generally mild and resolve within a few days.

How to Use

Usage method of Olvance 40mg

Follow all the directions given to you by your healthcare specialist. They will tell you how much of this medicine you need to take every day. This generally depends on your condition and whether you are taking any other medications. If you do not understand the instructions given on your prescription, consult your doctor for help. For most adult patients, the usual starting dose is 20 mg once a day. The dose may need to be increased to 40 mg once a day if necessary. It doesn’t matter whether you take the medicine with or without food.

For children aged 6 to 18 years, the recommended daily dose is one 20 mg tablet. The dose for children usually depends on your child’s weight. Swallow the tablet with a glass of water. Avoid chewing the tablet. Preferably, take the tablet at the same time each day, as this way the medicine will have the best effect. It will also help you remember to take the medicine. Olvance helps to control the condition but is not meant to cure it. Therefore, you must take the medication every day. Continue taking the medicine for as long as your doctor advises.

Infographics

FAQ

What is Olvance 40mg and who is it prescribed for?

Olvance 40mg is a once-daily angiotensin receptor blocker (ARB) tablet containing olmesartan medoxomil 40 mg, prescribed for adults with hypertension who require a higher-strength ARB to achieve blood pressure targets. It is a cost-effective generic equivalent of Benicar 40mg, used when the 20 mg starting dose proves insufficient. Olvance 40mg is appropriate for patients with moderate to severe hypertension, and it may also provide kidney protection in those with diabetic nephropathy.

What is the mechanism of action of olmesartan in Olvance 40mg?

Olvance 40mg works via olmesartan medoxomil, which converts to active olmesartan in the gut wall. Olmesartan selectively and irreversibly blocks AT1 angiotensin II receptors in vascular smooth muscle and the adrenal cortex. This prevents angiotensin II from triggering vasoconstriction and aldosterone release, resulting in vaSodiumilation and reduced fluid retention — ultimately lowering systolic and diastolic blood pressure without affecting heart rate or causing the cough typical of ACE inhibitors.

What is the recommended dosage schedule for Olvance 40mg?

Olvance 40mg is taken as one tablet once daily, with or without food. It should be taken at a fixed time each day for consistent blood pressure control. The 40 mg dose is the maximum approved daily dose for adults. If you forget a dose, take it as soon as you remember the same day; if you remember the next day, skip the missed dose and resume your regular schedule. Do not take double doses to compensate.

How soon will Olvance 40mg bring my blood pressure under control?

Olvance 40mg begins working shortly after the first dose, with blood pressure reductions measurable within a few hours. Stable, sustained control typically develops over 1–2 weeks as the drug reaches steady-state concentrations. If blood pressure remains elevated after four weeks at 40 mg, your physician may consider adding a complementary agent — such as a diuretic or calcium channel blocker — rather than increasing the olmesartan dose beyond 40 mg.

Is Olvance 40mg safe if I am also on a water pill (diuretic)?

Olvance 40mg can be safely used with thiazide diuretics, and this combination is common in managing resistant hypertension. However, diuretic-induced volume depletion can increase the risk of hypotension when starting olmesartan. If you're already taking a diuretic, your doctor may temporarily reduce the diuretic dose or start with olmesartan 20 mg first. Avoid potassium-sparing diuretics without close monitoring, as the combination can cause dangerously high potassium levels.

Can Olvance 40mg cause kidney problems in older adults?

Olmesartan in Olvance 40mg is generally kidney-protective in hypertensive patients, particularly those with early diabetic nephropathy. However, in elderly patients with reduced baseline kidney function or significant renal artery stenosis, olmesartan can occasionally worsen renal function. Older adults are also more susceptible to hypotension from ARBs. Routine monitoring of serum creatinine, eGFR, and potassium is recommended for elderly patients on Olvance 40mg.

How does Olvance 40mg compare to valsartan 80mg?

Both Olvance 40mg (olmesartan) and valsartan 80mg are ARBs for hypertension, but head-to-head studies generally show olmesartan provides a greater blood pressure reduction. A key clinical advantage of olmesartan is its tight, long-lasting AT1 receptor binding, which supports more consistent 24-hour coverage. Valsartan is available in combination products (e.g., with HCTZ or sacubitril) and is commonly used in heart failure as well, giving it broader indications in some patients.

Is Olvance 40mg better than telmisartan for blood pressure control?

Olvance 40mg and telmisartan 40–80 mg are both potent ARBs with once-daily dosing. Some comparative studies suggest olmesartan provides a stronger reduction in systolic blood pressure, while telmisartan has a longer half-life (24 hours vs. olmesartan's 13 hours) which may offer advantages for patients with early-morning blood pressure surges. The best choice depends on individual patient factors, tolerability, co-existing conditions, and cost considerations.

Where can I order Olvance 40mg online with authentic quality assurance?

Olvance 40mg can be ordered from PremiumRxDrugs.com, a licensed pharmacy trusted by customers in the USA, UK, Australia, and many other countries for over a decade. We supply only authentic, manufacturer-sourced olmesartan tablets at competitive prices. Every order is dispatched in discreet packaging, with free shipping available on qualifying orders and easy online prescription submission for your convenience.

Why do patients choose PremiumRxDrugs.com for olmesartan 40mg?

Patients across the USA, UK, and Australia choose PremiumRxDrugs.com for olmesartan 40mg because of its decade-long track record of reliability, manufacturer-verified medicine authenticity, and pricing that's significantly lower than branded Benicar. Free shipping, discreet delivery, and a simple prescription management system mean patients can maintain consistent treatment without overspending. For long-term hypertension management, these practical benefits genuinely make a difference.

What adverse effects should I be aware of with Olvance 40mg?

Olvance 40mg is well-tolerated in most patients. The most frequently reported adverse effects include dizziness (especially postural), sinusitis, back pain, and mild elevation in blood urea nitrogen. A small subset of long-term olmesartan users develops olmesartan-induced enteropathy — resembling coeliac disease with watery diarrhoea, nausea, and weight loss — that completely resolves after discontinuing the drug. If you experience persistent gastrointestinal symptoms, consult your prescriber.

Who should not use Olvance 40mg, and what precautions are necessary?

Olvance 40mg is contraindicated in pregnancy from the second trimester onward — olmesartan can cause fetal renal dysplasia, oligohydramnios, and death. It should not be co-administered with aliskiren in diabetic or renally impaired patients. Patients with hereditary angioedema or prior angioedema with an ARB should be monitored carefully. Those with severe renal artery stenosis or primary hyperaldosteronism may not respond adequately. Always discuss contraindications with your prescriber before starting.

Olvance 40mg