Prasita 10mg
| SKU | 815 |
|---|---|
| Generic For | Prasita |
| Strength | 10 mg |
| Manufacturer | Sun Pharma Laboratories Ltd |
| Active Ingredient | Prasugrel Hcl |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.41 | US$ 12.1850%US$ 24.32 | |||
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| 60 Tablet/s | US$ 0.41 | US$ 24.3750%US$ 48.65 | |||
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| 90 Tablet/s | US$ 0.41 | US$ 36.5550%US$ 72.97 | |||
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Prasita 10mg (Prasugrel Hcl)
Prasita 10 mg consists of active ingredient Prasugrel HCL. A thienopyridine derivative, Prasugrel is a P2Y12 platelet inhibitor structurally and pharmacologically associated with Ticlopidine and Clopidogrel. Similar to Clopidogrel, Prasugrel HCL is a prodrug theta needs an enzymatic transformation in the liver to R-138727, its active metabolite. R-138727 irreversibly adheres to P2Y12 type Adenophosphate receptors on platelets, therefore, preventing activation of the GPIIb/IIIa receptor complex. As a result, hindering of ADP-mediated platelet aggregation and activation occurs.
What is Prasita 10 mg used for?
Prasita 10 mg is used to prevent serious problems of the blood vessels and heart in people who have had severe chest pain or heart attack and have been treated with angioplasty. Prasugrel HCL is used in combination with Aspirin.
How does Prasita work?
Prasita works by preventing platelets from collecting and forming clots that may cause a stroke or a heart attack.
What medications interact with Prasita?
Avoid consuming Prasita, if you are taking the medicines that are given below:
- Warfarin, a medicine used in the prevention of blood clots
- NSAIDs
When should Prasita not be used?
Tell the doctor, before consuming the medicine:
- If you are hypersensitive to the drug, or its components.
- If you are suffering from blood diseases.
- If you are consuming any prescription or nonprescription medicines.
- If you are hypersensitive to some food products.
- If you are under 18 years of age.
- If you have recently undergone surgery.
- If you have been told by your doctor that you have an intolerance to some sugars, consult your doctor before taking the medicine.
- If you have a recent surgery.
- If your weight is less than 60 kg.
- If you have ever had a transient ischaemic attack.
- If you are suffering from severe liver disorders.
- If you are suffering from kidney disorders.
- If you are suffering from intestinal ulcers.
- If you are a woman of childbearing potential. You should discuss the positives and negatives of taking Prasita, at the time of pregnancy.
- Breastfeeding women are advised not to take Prasita as it may pass into the breast milk and harm the nursing baby.
- The drug may cause dizziness. Do not drive or use machinery, while taking Prasita as these activities may require a high degree of mental attention.
How should Prasita be stored?
- Do not forget to see the expiry date of the product.
- Store Prasita at a room temperature, away from heat and moisture.
- Always keep the written record of your medications.
- Avoid freezing the tablets.
- Do not share your medicines with your near and dear ones.
- Keep the tablets where children cannot reach it.
- Do not store the tablets in the bathroom or near a sink.
How should Prasita be taken?
- The drug is available in the form of tablets. Prasita is taken as a single dose. It may be taken without regard to food, or as your physician suggests. Swallow the medicine whole with an adequate amount of water.
- Take Prasita tablets strictly according to your doctor’s instruction. Do not alter the dosage plan unless your physician advice you to do so.
- Take the medicine regularly to get the best results.
- To help you remember, take the tablets at the same time each day.
- In some cases, the condition may become worse when the intake of the medicine is stopped suddenly. Your dose may need to be slowly decreased.
- Overdose: Seek medical attention immediately, in the case of an overdose of Prasita. You may experience:
- Vision problem
- Difficulty walking
- Blood in vomit and stools
- Appearance of water in the eyes
- Take the tablets for as long as your physician recommends.
Missed dose of Prasita:
If you have forgotten a dose, take it as soon you remember and go back to your usual dosing schedule. If the time to take the next dose is near, leave the forgotten dose and take the next dose. Do not double the dose to compensate the forgotten one.
What are Side effects of Prasita?
The common adverse effects of the drug are as follows:
- Headache
- Blood in vomit and cough
- Blood in stools
- Pain in the chest
- Weakness
- Easy bleeding
- Fever
- Yellowing of eyes and skin
- Speech problems
- Imbalance
Some other less common adverse reactions of Prasita are as follows.
- Pain in the back
- Tiredness
- Nausea
- Minor pain in the chest
- Mild headache
- Cough
If any of the above conditions persist or deteriorate, Contact your physician immediately.
What is prasugrel (Prasita 10mg) used for?
Prasita 10mg contains prasugrel, a potent P2Y12 antiplatelet agent prescribed to reduce the risk of heart attack and stroke in patients with acute coronary syndrome (ACS) who are managed with percutaneous coronary intervention (PCI/stenting). Prasugrel irreversibly blocks ADP receptors on platelets, preventing clot formation in coronary arteries and stent thrombosis. It is generally used alongside low-dose aspirin as dual antiplatelet therapy.
How does prasugrel work differently from clopidogrel?
Prasugrel is a third-generation thienopyridine that is more rapidly and consistently converted to its active metabolite than clopidogrel. It achieves faster, more complete, and more predictable platelet inhibition because it bypasses CYP2C19 metabolism — the step where clopidogrel's effectiveness varies between patients. In clinical trials (TRITON-TIMI 38), prasugrel reduced major cardiovascular events more effectively than clopidogrel in ACS-PCI patients, at the cost of a modestly higher bleeding risk.
What is the standard dose and schedule for Prasita 10mg?
The standard dose of prasugrel is a 60 mg loading dose at the time of PCI, followed by 10 mg once daily as maintenance therapy. Prasita 10mg is the once-daily maintenance tablet, taken with or without food at a consistent time each day. Patients weighing under 60 kg or aged 75 and over may be prescribed a 5 mg maintenance dose instead. Always follow your cardiologist's exact dosing instructions.
How long does it take for prasugrel to start inhibiting platelets?
Prasugrel begins working rapidly — meaningful platelet inhibition occurs within 30 minutes of the loading dose, making it useful in time-sensitive coronary interventions. Maximum platelet inhibition is achieved within 1–2 hours. The 10 mg maintenance dose maintains consistent day-to-day platelet suppression. Because prasugrel's antiplatelet effect is irreversible, the platelet function recovers only as new platelets are produced, which takes 5–7 days after stopping the drug.
Is prasugrel safe to continue long-term after stenting?
Dual antiplatelet therapy with prasugrel and aspirin is generally recommended for 12 months after drug-eluting stent placement to prevent stent thrombosis. Long-term use beyond 12 months may be considered in high ischaemic risk patients, but this must be weighed against bleeding risk on an individual basis. Prasugrel carries a higher bleeding risk than clopidogrel, particularly in patients over 75, those weighing under 60 kg, and those with prior stroke or TIA — in whom it is generally avoided.
Can prasugrel be taken with other blood thinners or NSAIDs?
Combining prasugrel with other anticoagulants (warfarin, heparin, direct oral anticoagulants) or NSAIDs significantly increases the risk of serious or life-threatening bleeding. If triple therapy is unavoidable — as in patients with atrial fibrillation who also need antiplatelet therapy — the combination should be kept as brief as possible under specialist oversight. Inform all your healthcare providers that you are on prasugrel before any procedure, including dental work.
How does Prasita 10mg compare to Brilinta (ticagrelor) for ACS?
Prasita 10mg (prasugrel) and Brilinta (ticagrelor) are both more potent P2Y12 inhibitors than clopidogrel. Ticagrelor is reversible and does not require metabolic activation; prasugrel is irreversible and prodrug-dependent. PLATO trial data shows ticagrelor has a mortality benefit over clopidogrel; TRITON data shows prasugrel reduces stent thrombosis and MI. For PCI-treated ACS, prasugrel is often preferred for its predictable, rapid onset; ticagrelor may be used in both PCI and medically managed ACS.
Is Prasita 10mg as effective as the branded Effient (prasugrel)?
Yes. Prasita 10mg contains the same active ingredient — prasugrel hydrochloride 10 mg — as Effient, manufactured to bioequivalence standards. Both inhibit platelets identically and provide the same cardiovascular protection in ACS patients post-PCI. The key advantage of Prasita is its significantly lower cost compared to branded Effient, making long-term daily antiplatelet therapy more financially manageable.
Can I order prasugrel online and have it delivered internationally?
Yes. PremiumRxDrugs.com ships prasugrel tablets — including Prasita 10mg — to the USA, UK, Australia, and many countries worldwide. The licensed pharmacy provides genuine manufacturer-verified antiplatelet medicines at competitive prices with discreet packaging and free worldwide shipping on qualifying orders. The prescription reorder system ensures uninterrupted access to this critical post-PCI medication.
What are the most important side effects of prasugrel 10mg?
The most significant side effect of prasugrel is bleeding — ranging from minor bruising and prolonged bleeding from cuts to serious gastrointestinal, intracranial, or surgical bleeds. Hypersensitivity reactions including angioedema are rare but reported. Thrombotic thrombocytopenic purpura (TTP) is a very rare but serious adverse reaction that requires immediate medical attention if symptoms of dark urine, neurological changes, or low platelet signs appear. Report unusual bleeding to your doctor promptly.
Who should not take prasugrel, and what precautions apply?
Prasugrel is contraindicated in patients with a history of stroke or TIA, active pathological bleeding, and severe hepatic impairment. It is generally avoided in patients aged 75 and over (except in high-risk diabetic or post-MI patients), and in those weighing under 60 kg unless the 5 mg dose is used. Stop prasugrel at least 7 days before elective surgery to allow platelet function to recover. Never discontinue prasugrel after stenting without cardiologist guidance — abrupt cessation dramatically increases stent thrombosis risk.
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