Rasalect 1mg
| SKU | 873 |
|---|---|
| Generic For | Azilect |
| Strength | 1 mg |
| Manufacturer | Intas |
| Active Ingredient | Rasagiline |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.56 | US$ 16.89 | |||
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| 60 Tablet/s | US$ 0.56 | US$ 33.78 | |||
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| 90 Tablet/s | US$ 0.56 | US$ 50.68 | |||
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Rasalect 1mg (Rasagiline) – Affordable Azilect Alternative
Rasalect 1 mg tablets contain the active ingredient Rasagiline, a monoamine oxide inhibitor, which is used for the treatment of Parkinson’s disease. The drug stops the breakdown of some crucial compounds in the brain, called neurotransmitters. These neurotransmitters are serotonin, norepinephrine, and dopamine. It can be used along with or without Levodopa (another drug that is used to treat Parkinson’s disease).
What is Rasalect used for?
Rasalect 1mg, being an anti- Parkinson’s disease medicine used to treat critical signs and symptoms of Parkinson’s disease. It exhibits anti-apoptotic and neuroprotective activity against several neurotoxins.
Parkinson’s disease is the central nervous system disease that affects the motor activity of the brain. This disease of the central nervous system is defined by the indefinite movement, tremor, shaking of legs, and muscle weakness. The disease is characterized by the loss of functions of the tissues and organs.
How does Rasalect work?
Rasalect 1 mg tablets contain the active ingredient Rasagiline, which is an irreversible monoamine oxidase inhibitor with Parkinson activity. In Parkinson's disease, there is a loss of cells that produce a chemical compound dopamine in the brain. Dopamine maintains the chemical balance inside the brain. Reduced level of dopamine affects the body movements. The symptoms of decreased dopamine level are tremors and shaking of legs. The administration of Rasagiline slowly increases the level of dopamine and ultimately results in improved muscle balance.
What are the medications interact with Rasalect ?
Many drugs can interact with Rasalect 1 mg to create adverse health issues. You should, thus, avoid these medicines in combination with Rasalect :
- Antidepressants
- Isocarboxazid
- Phenelzine
- Linezolid
- Ephedrine
- Tryptophan
- Nasal decongestants
- Procarbazine
- Zolmitriptan
- Phenylephrine
- Sumatriptan
- Ephedra
- Ephedra
- Antibiotic ciprofloxacin
- Cold or allergy drugs
The list is not complete, ask your physician to provide you a full list of drugs that may negatively interact with Rasalect and avoid these drugs. If you are already taking these drugs, then inform your physician about it.
When should Rasalect not be used?
- Rasalect 1 mg should not be given to patients with known hypersensitivity to Rasagiline or to other MAO inhibitors.
- Concomitant use of meperidine, methadone, propoxyphene, St. John’s wort, cyclobenzaprine, and dextromethorphan is contraindicated.
Do not take this drug if any of the above applies to you. If you are not sure, talk to your physician before taking this medicine.
How should Rasalect be taken?
- Rasalect 1 mg is present in the form of a tablet. It should be administered orally once in a day as 1 mg or 0.5 mg once every day in combination with another drug.
- Avoid crushing and chewing the tablet. Try to swallow the tablet with a glass full of water. You can take it without regard to food. Never stop the dose or change the dose without your physician's advice, as it may cause adverse reactions or withdrawal symptoms.
- Do not skip doses or stop using Rasalect tablets suddenly. Stopping the medicine suddenly may make your condition worse.
- If accidently you take an overdose of the drug then you must inform your physician immediately. In case if you feel any discomfort visit the physician immediately. An accidental overdose of Rasalect may cause symptoms like breathing difficulties, motor incoordination, severe headache, dizziness, faintness, shivering, hallucinations, drowsiness, agitation, and hyperactivity, etc.
- The dosage regimen may differ from the information contained in this document. In the case of any confusion, please consult your physician.
How long should you take Rasalect ?
Continue taking Rasalect 1 mg for as long as your physician recommends. Do not take longer than prescribed without checking your physician.
Missed Dose of Rasalect
Take the missed dose as soon as you remember. Leave the missed dose if it is almost time for your next dose. Do not take an extra dose to make up the missed one. Try to take the drug at the same time each day as this will reduce the chance of missing the dose.
How should Rasalect be stored?
- It should be stored at room temperature
- Keep it out of the reach of children and away from pets. Avoid exposure to light, moisture, and heat
- Do not place it in the bathroom or near a sink.
What are the side effects of Rasalect ?
Rasalect 1 mg tablets are generally well tolerated, but it is always possible that you may experience side effects. The most common side effects include: nausea, fever, burning sensation in heart, dry mouth, joint pain, dizziness, and abdominal pain, etc.
Some other side effects are:
- Confusion
- Decreased sexual ability
- Sudden weight loss
- Trouble thinking or walking
- Tremors
- Speech problems
- Swelling of the hands, legs, and ankles
- Pounding heartbeat
- Sweating
- Clammy skin with severe nausea, vision problem, dilated pupils, sudden sensitivity to light, neck stiffness, or soreness, etc.
What is Rasalect 1mg used for?
Rasalect 1mg contains rasagiline 1mg — a selective, irreversible MAO-B (monoamine oxidase B) inhibitor for treating Parkinson's disease. It is used as monotherapy in early Parkinson's disease or as adjunct therapy to levodopa in more advanced disease. Rasagiline inhibits the enzyme that breaks down dopamine in the brain, prolonging dopamine's availability and reducing Parkinson's motor symptoms (tremor, rigidity, bradykinesia). It is taken once daily — simple dosing that improves adherence in this largely elderly population.
How does rasagiline improve Parkinson's disease symptoms?
MAO-B is the primary enzyme responsible for dopamine breakdown in the striatum. Rasagiline irreversibly inhibits MAO-B, preventing dopamine degradation and increasing its availability at dopaminergic synapses. In early Parkinson's disease, this provides modest symptomatic improvement without levodopa. As an adjunct to levodopa in advanced disease, it extends and smooths levodopa's effect — reducing 'off' time (periods of poor motor control) by approximately 1.5 hours/day. Rasagiline may also have neuroprotective effects (debated in clinical trials).
How should Rasalect 1mg be taken?
Rasalect 1mg is taken once daily — at any consistent time, with or without food. The once-daily regimen is a significant practical advantage in Parkinson's patients, who often manage complex multi-medication regimens. No dose adjustment is required for the standard 1mg dose in patients with mild hepatic impairment; avoid in moderate-severe hepatic impairment. Avoid concurrent use with certain antidepressants (SSRIs, SNRIs, TCAs), ciprofloxacin (increases rasagiline levels), and meperidine (pethidine). The irreversible MAO-B inhibition lasts 2–4 weeks after stopping.
How long does Rasalect 1mg take to improve Parkinson's symptoms?
Rasagiline's symptomatic effects are generally modest but meaningful in early Parkinson's disease — improvement in UPDRS motor scores of 3–5 points compared to placebo at 12–26 weeks. As levodopa adjunct: reduction in daily 'off' time of approximately 1–1.5 hours/day is typically measurable within 4–12 weeks. Motor function improvements in activities of daily living occur in parallel. Rasagiline's irreversible mechanism means its effect builds progressively — full clinical benefit is typically assessed at 3 months.
Is rasagiline monotherapy sufficient for early Parkinson's disease?
Rasagiline 1mg monotherapy provides modest motor improvement in early Parkinson's disease — it delays the need for levodopa therapy by approximately 9–12 months in some patients. The ADAGIO trial investigated whether early rasagiline treatment had disease-modifying effects — results were inconclusive. Rasagiline is appropriate as monotherapy in patients with mild motor symptoms who do not yet need levodopa's more powerful dopaminergic effect. As disease progresses, levodopa or dopamine agonists are added, with rasagiline continued as an adjunct.
What interactions does rasagiline have with antidepressants?
Rasagiline, as an MAO inhibitor, carries a risk of serotonin syndrome when combined with serotonergic antidepressants. Selective MAO-B inhibitors at approved doses pose lower risk than non-selective MAOIs, but caution is still warranted. SSRIs (fluoxetine, sertraline) and SNRIs (venlafaxine, duloxetine) should be used with caution — though clinical serotonin syndrome is rare with rasagiline monotherapy at 1mg. TCAs are similarly cautioned. St John's Wort is contraindicated. Meperidine (pethidine) is contraindicated — fatal interactions have been reported with MAO inhibitors.
How does Rasalect 1mg compare to selegiline for Parkinson's disease?
Both rasagiline (Rasalect) and selegiline are MAO-B inhibitors for Parkinson's disease. Rasagiline has several advantages: once-daily dosing vs. twice daily for selegiline; rasagiline is not metabolised to amphetamine (selegiline produces amphetamine and methamphetamine metabolites that can cause insomnia and cardiovascular effects); and rasagiline has larger, more robust clinical trial evidence (PRESTO, LARGO, ADAGIO). Most movement disorder specialists consider rasagiline the preferred MAO-B inhibitor for both monotherapy and adjunct use.
Is Rasalect 1mg equivalent to Azilect 1mg?
Yes. Rasalect 1mg and Azilect 1mg both contain rasagiline 1mg — identical active ingredient and dose — manufactured to bioequivalence standards. Azilect is the branded formulation developed by Teva; Rasalect is the generic version providing the same MAO-B inhibition and Parkinson's symptom benefit at significantly lower cost. For patients on long-term Parkinson's disease medication management, generic rasagiline provides important cost savings.
Can I order Rasalect 1mg from PremiumRxDrugs for delivery to the USA?
Yes. PremiumRxDrugs.com ships Rasalect 1mg to the USA, UK, Australia, and many other countries. Our genuine manufacturer-verified Parkinson's medications, competitive pricing, and free worldwide shipping on qualifying orders make us a trusted international pharmacy for patients managing Parkinson's disease with MAO-B inhibitor therapy.
What side effects does Rasalect 1mg cause?
As monotherapy: headache, arthralgia, dyspepsia, and depression are the most commonly reported side effects. Accidental injuries are more common, possibly reflecting Parkinson's disease itself. As levodopa adjunct: dyskinesias (involuntary movements), orthostatic hypotension, weight loss, and hallucinations can occur — these are largely levodopa-related effects potentiated by increased dopamine from rasagiline. Melanoma risk: patients with Parkinson's have increased melanoma incidence — regular skin examination is recommended during rasagiline therapy.
What precautions apply to Rasalect 1mg users?
Avoid meperidine (pethidine) — contraindicated. Use SSRIs/SNRIs with caution. Monitor for serotonin syndrome symptoms (fever, agitation, muscle twitching, diarrhoea). Avoid ciprofloxacin (doubles rasagiline exposure). Avoid tyramine-rich foods in large amounts, though the selectivity of MAO-B means the tyramine restriction is much less strict than with non-selective MAOIs. Monitor blood pressure — orthostatic hypotension can occur, particularly as levodopa adjunct. Regular skin examination for melanoma. Annual ophthalmic review recommended.
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