Sazo EN (sulfasalazine ) 500mg

Sazo EN500 mg (Sulphasalazine)

Scientists have been specially formulated Sazo EN for people who are suffering from rheumatoid arthritis. A health care specialist may also prescribe this medication to treat other health disorders like Chrohn’s disease, Psoriatic arthritis, and ulcerative colitis. The active component of the medicine is Sulfasalazine, which is known to have anti-inflammatory effects and to decrease the action of the immune system. Its regular administration to patients with rheumatoid arthritis reduces pain and swelling. By limiting joint damage, it prevents disability in the long term. The medicine falls into the category of drugs known as disease modifying anti-rheumatic drugs (DMARDs). It not only relieves the pain during arthritis but also reduce the damage to the joints.

What is Sazo EN used for?

Sazo EN is useful in treating mild to moderate ulcerative colitis or as adjunctive treatment in severe ulcerative colitis. You will also get this medication to treat your rheumatoid arthritis unresponsive or intolerant to non-steroidal anti-inflammatory drugs and salicylates.

How does Sazo EN work?

The medication exerts its anti-inflammatory action in the colon and works by reducing the symptoms of ulcerative colitis or rheumatoid arthritis.

Where to buy Sazo EN online?

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What does Sazo EN contain?

The active component is Sulfasalazine. Each capsule contains 500 mg of the active substance. 

What are the side effects of Sazo EN?

• Gastrointestinal issues- diarrhea, vomiting, nausea, drug induced hepatitis, anorexia
• Dermatological issues- photosensitivity, stevens-johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis, yellow discoloration.
• Neurological issues- peripheral neuropathy
• Genitouterine disorders- infertility, orange yellow discoloration of urine, oligospermia, crystalluria, infertility
• Miscellaneous issues- Hypersensitivity reactions including fever, anaphylaxis

What medications interact with Sazo EN?

• Sazo EN may cause toxicity from oral hypoglycemic medications such as zidovudine, warfarin, methotrexate, or phenytoin.
• There is a risk of crystalluria with concurrent use with methenamine.
• Drug induced hepatitis may develop if used along with hepatotoxic agents.
• Your anti-rheumatic drug may increase toxicity if used with thioguanine or mercaptopurine.

How should Sazo EN be used?

Ulcerative colitis

For adults- The recommended initial dose is 500 mg every 12 hours. The recommended maintenance dose is 500 mg every six hours.

For children above two years of age- The initial recommended dose is 6.7 to 10 mg/kg every 4 hr or 10 to 15 mg/kg every 6 hours or 13.3 to 20 mg/kg every 8 hour. 7.5 mg/kg every 6 hour is the preferred maintenance dose. The maximum dose should not exceed 2 g daily.

Rheumatoid Arthritis

For adults- The recommended dose is 500 mg to 1 g daily for one week. Your health care specialist may then increase your dose by 500 mg daily every week to 2 g daily in two divided doses. In case there are no results seen after a period of 12 weeks, the dose may increase to 3 g daily and must be given in two divided doses.

For children above six years of age- 30 to 50 mg/kg daily is the suggested dose which should be given in two divided doses. The maximum dose must not exceed 2 g daily.

When should Sazo EN not be used?

• The anti-rheumatic medication is not made for patients who are hypersensitive to salicylates, sulphonamides, sulfasalazine, or other excipients of the medication.
• Porphyria
• Urinary tract or intestinal obstruction
• pediatrics

How long should Sazo EN be used?

Treatment with Sazo EN- 500 mg should be continued as long as a patient continues to benefit or as prescribed by the physician. Do not stop the treatment otherwise; you will not get rid of rheumatoid or ulcerative colitis.

Missed dose of Sazo EN

If you are using Sulfasalazine (Sazo EN) on a regular basis and miss a dose, take that dose as when you remember on an empty stomach. The missed dose should not be taken if the time to take the next dose is near. Do not take a double dose to make up for any missed dose.

How should Sazo EN be stored?

Store the tablets out of the reach of children, away from heat, light, and moisture. Keep it at room temperature. Do not keep the tablets near the window sill as heat can destroy some medications.