Seroflo Inhaler 25 mcg 250 mcg (120 mdi)
Available Dosages
| SKU | 924 |
|---|---|
| Generic For | Advair Inhaler |
| Strength | 25 mcg + 250 mcg (120 mdi) Inhaler |
| Active Ingredient | Salmeterol + Fluticasone Propionate |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 1 Inhaler | US$ 25.00 | US$ 25.00 | |||
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| 2 Inhaler/s | US$ 21.00 | US$ 42.0016%US$ 50.00 | |||
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| 3 Inhaler/s | US$ 21.00 | US$ 63.0016%US$ 75.00 | |||
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Seroflo Inhaler 25 mcg 250 mcg (120 mdi) – Advair Inhaler Alternative
Seroflo Inhaler 250mcg asthma medications contain the active ingredients, salmeterol xinafoate and fluticasone propionate, which provides relief of the symptoms of and prevents asthma attacks, treats chronic bronchitis, and disorders of the pulmonary glands.Salmeterol xinafoate and fluticasone propionate keep in check and prevents symptoms such as wheezing and shortness of breath caused by asthma. Salmeterol is a long lasting beta controller and Fluticasone is a corticosteroid, together they prevent asthma attacks and reduce inflammation in the lungs allowing the airways to open up. This medication will not stop an asthma attack that is in progress.
How does Seroflo Inhaler 250 mcg work?
Seroflo Inhaler 250 mcg asthma contains Salmeterol xinafoate and fluticasone propionate works by relaxing the muscles of lungs and reducing swelling and irritation of the air passages, and preventing inflammation that causes constriction of the airways, allowing trouble-free breathing.
What medications interact with Seroflo Inhaler 250mcg ?
Tell your doctor what if any medications you take. Ask your physician or pharmacist for a list of drugs, when using Seroflo, should not be taken:
Some drugs that can interact with salmeterol xinafoate and fluticasone propionate include:
- Xanthenes
- Telithromycin
- Sympathomimetics drugs
- Nefazodone
- Macrolides
- Linezolid
- HIV protease inhibitors
- diuretics
- Digitalis
- Boceprevir
- beta blockers
- antifungal medications such as ketoconazole
This is not a completel list of medications that could cause a possible drug interaction. Your physician or pharmacist can provide a complete list. If you have any questions ask your doctor or pharmacist.
When should Seroflo Inhaler not be used?
Do not use Seroflo Inhaler if you have any of these medical conditions without consulting with your physician.
· Suffer from Paradoxical respiration or breathing
- Myocardial insufficiency
- Have epilepsy
- Have diabetes
- Have cardiovascular diseases
- Allergic to any of the ingredients of salmeterol xinafoate and fluticasone propionate
How should Seroflo 250 mcg Inhaler spray be used?
Seroflo Inhalers are intended to be taken by inhalation only. It is important to rinse the mouth inhalation of the medication to avoid throat irritation and dry mouth.
Try to take your dose of medicine at the same time each day. This is important for two reasons:
- For optimal results of medication
- So you remember to take your medication every day
Clean the inhaler after use, remove dirt and debris to avoid contamination of medication.
The prescribed amount is usually one or two puffs to prevent an asthma attack. Do not take more or less than the amount prescribed by your physician.
How long should you use Seroflo Inhaler?
Use Seroflo Inhaler as long as it is prescribed. Your physician will need to track your progress on a regular basis. Do not miss any scheduled visits to your physician.
What is Seroflo 25/250mcg inhaler used for?
Seroflo 25/250mcg contains salmeterol 25mcg and fluticasone propionate 250mcg per actuation — the higher-strength pMDI formulation. It is used for maintenance treatment of moderate-to-severe asthma in adults and adolescents who are not adequately controlled on lower-dose ICS/LABA combinations or on high-dose ICS alone. The higher fluticasone dose provides greater anti-inflammatory control in patients with more severe airway inflammation or frequent symptom breakthrough.
How is 25/250mcg different from 25/125mcg Seroflo?
The salmeterol component (25mcg per puff) is identical in both strengths. The difference is the fluticasone propionate dose: 125mcg per puff in the lower strength vs 250mcg per puff in the higher strength. The 25/250mcg formulation delivers twice the anti-inflammatory steroid component per actuation, providing stronger airway inflammation control. It is stepped up to when 25/125mcg does not achieve adequate symptom control. Maximum benefit is usually achieved over 2–4 weeks of regular use.
What is the correct dose of Seroflo 25/250mcg for adults?
The standard adult dose of Seroflo 25/250mcg is 2 puffs twice daily — morning and evening — giving a total daily dose of salmeterol 100mcg and fluticasone 1000mcg. Shake well before each use, exhale fully, inhale deeply while actuating, and hold breath for 10 seconds. Rinse mouth after each use. Do not exceed the prescribed dose. Your doctor may adjust the dose based on asthma control assessment; the aim is always to achieve control at the lowest effective ICS dose.
How long does it take Seroflo 25/250mcg to fully control moderate-severe asthma?
Immediate bronchodilation from salmeterol begins within 10–20 minutes of inhalation. The anti-inflammatory effect of fluticasone 250mcg builds progressively over 1–4 weeks of consistent twice-daily use. Full asthma control — including reduction in nocturnal symptoms, reduced rescue inhaler use, and improved morning peak flow — is typically assessed at 4–8 weeks. Dose stepping down to 25/125mcg can be considered once stable control is achieved for 3 months.
Is the higher fluticasone dose in Seroflo 25/250mcg safe?
Fluticasone 250mcg per puff (500mcg/day with 2 puffs twice daily) is within the medium-high dose ICS range. At this dose, systemic exposure is low but not negligible — regular monitoring for steroid side effects is advisable for long-term users. Adrenal function testing may be warranted in patients on high-dose ICS for several years. Minimising systemic exposure by stepping down to 25/125mcg when good control is achieved is standard practice.
What should I do if Seroflo 25/250mcg doesn't control my asthma?
Persistent poor asthma control despite high-dose ICS/LABA warrants medical reassessment. Your doctor may check for: poor inhaler technique, non-adherence, trigger avoidance, comorbidities (rhinosinusitis, GORD, obesity), alternative diagnoses (COPD, vocal cord dysfunction), or need for add-on therapy (leukotriene antagonists, tiotropium, or biological agents such as monoclonal antibodies targeting IgE or IL-5). Never increase the dose beyond prescribed without medical guidance.
How does Seroflo 25/250mcg compare to Symbicort 160/4.5mcg?
Seroflo 25/250mcg (salmeterol/fluticasone pMDI) and Symbicort 160/4.5mcg (budesonide/formoterol DPI) are both ICS/LABA fixed combinations for asthma maintenance. Key differences: Seroflo uses a pMDI; Symbicort uses a DPI. Formoterol (in Symbicort) has a faster onset than salmeterol, making Symbicort suitable for SMART (single maintenance and reliever therapy). Fluticasone is more potent per mcg than budesonide. Both are effective options; selection depends on device preference, control level, and patient needs.
Is Seroflo 25/250mcg equivalent to Seretide 25/250mcg?
Yes. Seroflo 25/250mcg contains the same active ingredients — salmeterol 25mcg and fluticasone propionate 250mcg per actuation — as branded Seretide 25/250mcg. Manufactured to bioequivalence standards, both deliver equivalent drug deposition and clinical effect. Seroflo is the generic alternative that provides the same therapeutic benefit as Seretide at substantially lower cost — important for patients requiring long-term high-dose maintenance therapy.
Can I order Seroflo 25/250mcg from PremiumRxDrugs for delivery to the UK or Australia?
Yes. PremiumRxDrugs.com ships Seroflo 25/250mcg inhalers to the UK, Australia, USA, and many other countries. Our genuine medicines, competitive pricing, and free worldwide shipping on qualifying orders make us a dependable international pharmacy for patients managing moderate-to-severe asthma with combination ICS/LABA therapy.
What side effects does Seroflo 25/250mcg commonly cause?
At the higher fluticasone dose, the risk of oral candidiasis (thrush) and dysphonia (hoarseness) is somewhat higher — rinsing the mouth with water after every dose is essential. Salmeterol may cause tremor, palpitations, and headache. Systemic steroid effects (easy bruising, mild adrenal suppression) are more likely with prolonged high-dose use. Hypokalaemia is a risk with concurrent diuretics or repeated high-dose beta-agonist use. Report any significant weight gain, persistent infections, or mood changes.
What precautions are important for Seroflo 25/250mcg users?
Always rinse your mouth after each dose to prevent thrush. Never use as an emergency rescue inhaler. Continue using your short-acting salbutamol for acute breathlessness. Do not abruptly stop Seroflo. Keep a spacer device if coordination is difficult. At this higher ICS dose, annual bone density monitoring and growth checks in children are advisable for long-term users. Disclose all respiratory medications to your doctor to avoid inadvertent LABA monotherapy risk.
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