Seroflo Inhaler 25 mcg 125 mcg (120 mdi)
Available Dosages
| SKU | 923 |
|---|---|
| Generic For | Advair Inhaler |
| Strength | 25 mcg + 125 mcg (120 mdi) Inhaler |
| Active Ingredient | Salmeterol + Fluticasone Propionate |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 1 Inhaler | US$ 19.00 | US$ 19.00 | |||
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| 2 Inhaler/s | US$ 17.00 | US$ 34.0011%US$ 38.00 | |||
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| 3 Inhaler/s | US$ 17.00 | US$ 51.0011%US$ 57.00 | |||
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Seroflo Inhaler 25/125 mcg (120 mdi) – Affordable Advair Inhaler Alternative
Seroflo Inhaler 125 mcg is an effective combination that provides symptomatic relief and prevents chronic bronchitis, asthma, and chronic disease of the pulmonary gland. The inhaler comprises of two pharmaceutical active ingredients Fluticasone Propionate and Salmeterol. Fluticasone, a corticosteroid, is an anti-inflammatory component, whereas Salmeterol is a long-acting bronchodilator that treats constriction of the airways. The combination drug provides better control of asthma to protect against symptoms, prevent exacerbation of asthma or chronic obstructive disease and decrease inflammation in the lung by releasing the chemicals that open up the constricted tube.
What is Seroflo Inhaler 125 used for?
Seroflo inhaler 25 mcg 125 mcg contains a combination of two medications that works differently to control asthma symptoms and chronic obstructive pulmonary disease. The inhaler is a formulation, which is used to relieve airway spasm, wheezing, tightness in the chest, and shortness of breath and provide relief for up to 12 hours. It should not be used for severe asthma or an asthma attack that has already begun.
How does Seroflo Inhaler 125 work?
Both the drug works together to relieve the symptoms of wheezing, coughing, and shortness of breath, better than either Fluticasone or Salmeterol taken on its own.
The drug Fluticasone propionate is a synthetic, trifluorinated corticosteroid with antipruritic, antiallergic and anti-inflammatory properties. It prevents the release of certain substances in the body that causes inflammation.
Salmeterol is a selective beta adrenoreceptor agonist, which inhibits the release of certains chemicals like histamine, leukotriens, prostaglandin D2 and GM-CSF in concentration dependent manner.
What does Seroflo Inhaler 125 contain?
Seroflo inhaler contains Fluticasone Propionate and Salmeterol as the main active ingredients. Each metered dose contains 125 mcg of Fluticasone Propionate and 25 mcg of Salmeterol.
What medications interact with Seroflo Inhaler 125?
Seroflo inhaler 25 mcg 125 mcg may have an effect on working with other drugs, and other drugs may have an effect on the mechanism of action of Fluticasone Propionate and Salmeterol.
Please tell your doctor, if you are taking or have recently taken any other drugs, including drugs obtained without a prescription.
The following medicines should be avoided, in the case doctor prescribes you Seroflo inhaler to avoid possible drug interactions.
- Boceprevir
- Diuretics
- Linezolid
- Macrolides
- Telithromycin
- Macrolides
- Xanthenes
- Sympathomimetics drugs
- Atenolol
- Nefazodone
- Digitalis
- Ketoconazole
- Telithromycin
When should Seroflo inhaler not be used?
- Seroflo inhaler should not be used in patients with a known hypersensitivity to Fluticasone Propionate and Salmeterol
- It is not suitable for pregnant and breastfeeding women
- The inhaler is not indicated for patients with tuberculosis of the lung or other lung infection
- It is not recommended for diabetic patients
- Do not use it if you have pre-existing cardiovascular disease, high levels of thyroid hormone, or heart rhythm abnormality
What are the side effects of Seroflo inhaler?
Some common side effects of Seroflo Inhaler 125, include mild fever, nausea, bleeding of the nose, tightness in the chest, cough, vomiting, stuffy nose, hoarseness in the voice, sneezing, sores on the lips or mouth, and sinus pain.
The most commonly reported side effects of Salmeterol are given below:
- Nervousness
- Shaking hands
- Headache
- Inability to sleep
- Low potassium levels in blood
- Rash
- Very fast heart rate
How should Seroflo inhaler be used?
Use Seroflo inhaler by taking two puffs twice daily, morning and evening. The amount of dosage that you need to take to relieve COPD and asthma symptoms will depend on your condition and age. After analyzing all these factors, your physician will recommend the best therapeutic dose. Carefully follow all the instructions provided with your Seroflo inhaler:
- Firstly remove the mouthpiece and gently shake the inhaler
- Breathe out to make yourself comfortable and then place the mouthpiece in your mouth
- Press down on the inhaler to release the dose of the combination medicine while still breathing in until your lungs are full, and then hold your breath for a few seconds
- Then, remove the inhaler and breathe normally
- Replace the mouthpiece cover
- Rinse your mouth after every use
How long should you use Seroflo inhaler?
Always remember, the inhaler dose does not work immediately, it is a long term medication that may take up to a week to start to work and may take several weeks before you feel some improvement. Use your Seroflo inhaler on a regular basis to attain maximum relief and continue for as long as recommended by your physician.
Missed dose of Seroflo inhaler
Take the missed dose as soon as you remember. Skip the missed dose if the time to take the next dose is near and take the next dose at the scheduled time.
How should Seroflo inhaler be stored?
Seroflo inhaler should be stored at room temperature. Keep it in a dry place away from heat and moisture. Keep the inhaler away from the reach of children and pets.
What is Seroflo Inhaler 25/125mcg used for?
Seroflo Inhaler 25/125mcg contains salmeterol 25mcg and fluticasone propionate 125mcg in a pressurised metered-dose inhaler (pMDI). This combination is used for regular maintenance treatment of asthma in adults and children over 4 years who are not adequately controlled on inhaled corticosteroids alone, and for the maintenance treatment of COPD. Salmeterol is a long-acting beta-2 agonist (LABA) that opens airways; fluticasone reduces airway inflammation.
How does the salmeterol and fluticasone combination work for asthma?
Seroflo combines two complementary mechanisms. Salmeterol (LABA) binds to beta-2 receptors in airway smooth muscle, causing sustained bronchodilation lasting 12 hours — preventing bronchospasm. Fluticasone propionate (ICS) inhibits airway inflammation by suppressing eosinophil activation, cytokine release, and mucus hypersecretion. Together they reduce both the immediate and underlying inflammatory component of asthma, providing better control than either agent alone with fewer side effects at lower individual doses.
How should Seroflo 25/125mcg inhaler be used correctly?
Shake the inhaler well before each use. Breathe out fully, then place the mouthpiece between your lips and inhale slowly and deeply while pressing the canister. Hold your breath for 10 seconds. The standard adult dose is 2 puffs twice daily (morning and evening). Rinse your mouth with water and spit after each use to reduce the risk of oral thrush from the inhaled corticosteroid. Use a spacer device if you have difficulty coordinating the inhale with the actuation.
How quickly does Seroflo 25/125mcg start working?
Salmeterol has a slower onset of bronchodilation than short-acting beta-2 agonists (SABAs) like salbutamol — bronchodilation begins within 10–20 minutes and peaks at 30–60 minutes. Fluticasone's anti-inflammatory effects build over days to weeks of regular use. Seroflo should be used as a regular maintenance inhaler, not for acute symptom relief. Always keep a short-acting reliever inhaler (salbutamol) available for sudden breathlessness — Seroflo does not replace it.
Is Seroflo 25/125mcg safe for long-term daily use?
Seroflo 25/125mcg is approved for long-term daily maintenance use in asthma and COPD. The fluticasone dose in this formulation (125mcg per actuation) is low to medium, minimising systemic steroid exposure. Long-term side effects of inhaled corticosteroids — adrenal suppression, growth effects in children, bone density reduction — are significantly lower with inhaled than oral steroids. Regular peak flow monitoring, annual asthma review, and continued use of the lowest effective dose are recommended.
Who should not use Seroflo 25/125mcg inhaler?
Seroflo is not for use as an acute rescue inhaler. It should not be used as initial monotherapy in patients not yet on ICS, as LABA monotherapy in asthma without ICS increases mortality risk. It is contraindicated in patients with known hypersensitivity to salmeterol or fluticasone. Use with caution in patients with thyrotoxicosis, severe cardiovascular disease, or hypokalaemia. Pregnancy use requires individual risk-benefit assessment with a respiratory physician.
How does Seroflo 25/125mcg compare to Seretide 25/125mcg?
Seroflo 25/125mcg is the generic equivalent of branded Seretide 25/125mcg (Advair in the USA). Both contain identical active ingredients — salmeterol 25mcg and fluticasone propionate 125mcg per actuation — in a pMDI. They are manufactured to bioequivalence standards with equivalent clinical efficacy and safety profiles. Seroflo offers significant cost savings over branded Seretide, making long-term asthma maintenance therapy more affordable.
Is Seroflo better than using a LABA and ICS inhaler separately?
Fixed-dose combination inhalers like Seroflo offer practical advantages over separate LABA and ICS inhalers: simplified regimen (one inhaler instead of two), improved adherence, guaranteed co-administration, and often lower cost per dose. Fixed combinations also prevent the theoretical risk of patients using LABA without ICS (which is associated with increased asthma mortality). Most guidelines now recommend fixed ICS/LABA combinations as the preferred maintenance step for asthma requiring add-on therapy.
Can I order Seroflo inhaler from PremiumRxDrugs with delivery to my country?
Yes. PremiumRxDrugs.com ships Seroflo inhalers internationally to the USA, UK, Australia, and many other countries. Our genuine manufacturer-verified medicines, competitive pricing, and free worldwide shipping on qualifying orders makes us a reliable source for patients who require consistent daily maintenance treatment for asthma or COPD.
What are the common side effects of Seroflo 25/125mcg?
Common side effects include oral thrush (candidiasis) and hoarseness from inhaled fluticasone — minimised by rinsing the mouth after each dose. Salmeterol-related effects include palpitations, tremor, and headache. Throat irritation and cough are occasionally reported. With regular use, the systemic steroid-related effects are minimal at this dose level. Hypokalaemia (low potassium) can occur at high doses — relevant in patients on diuretics or other beta-agonists.
What precautions apply when using Seroflo 25/125mcg inhaler?
Always rinse your mouth and throat after each use to prevent oral thrush. Never use Seroflo for acute breathlessness — use your short-acting reliever (salbutamol). Do not stop Seroflo suddenly without medical advice, even if you feel well — stopping abruptly can trigger worsening asthma. Carry a written asthma action plan. If you need your reliever inhaler more than twice weekly, review your asthma management with your doctor. Report any unexplained weight gain or facial rounding to your doctor.
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