Syndopa CR 50 200 mg
| SKU | 186 |
|---|---|
| Generic For | Sinemet CR |
| Strength | 50 + 200 mg |
| Manufacturer | Wyeth Pharmaceuticals |
| Active Ingredient | Carbidopa Levodopa |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.47 | US$ 14.00 | |||
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| 60 Tablet/s | US$ 0.30 | US$ 18.0036%US$ 28.00 | |||
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| 90 Tablet/s | US$ 0.28 | US$ 25.0040%US$ 42.00 | |||
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Syndopa CR 50 200 mg is a controlled-release formulation that combines Carbidopa 50 mg and Levodopa 200 mg as the active ingredients. It is primarily used in the management of Parkinson’s disease and Parkinsonian-related symptoms, such as muscle stiffness, tremors, trouble maintaining balance, and slowness of movement. Levodopa is converted into dopamine, whose deficiency in the brain is the key factor behind Parkinson’s symptoms. By replenishing dopamine levels, Levodopa eases motor difficulties.
On the other hand, Carbidopa works to prevent the premature breakdown of Levodopa in the blood. Automatically, most of the Levodopa would convert into dopamine outside the brain, resulting in side effects and reduced effectiveness. Carbidopa ensures more Levodopa reaches the brain, thereby increasing effectiveness and reducing side effects such as nausea and vomiting. The controlled-release formulation is specially designed for the gradual release of the medication into the body, offering longer-lasting symptomatic relief. The combination helps restore the balance of dopamine in the brain, thereby improving the mobility and quality of life for patients with this chronic neurological disorder. Syndopa CR 50/200 is often recommended when Parkinson’s medications are not sufficient or when a controlled, sustained release of Levodopa is needed.
Things to take care of while using Syndopa CR 50 200 mg
Before initiating treatment with Syndopa CR 50/200mg, patients should inform their healthcare provider of their medical history and current medications. Key precautions include:
- Allergic reactions: Avoid taking Syndopa CR if you are allergic to Levodopa, Carbidopa or any other ingredients in the medicine.
- Pre-existing conditions: Use cautiously in patients with heart disease, liver or kidney impairment, peptic ulcer, asthma, glaucoma, seizures, or depression.
- Pregnant and breastfeeding: The safety and effectiveness of this medication have not been fully established. It should only be used in such cases if prescribed by a healthcare professional after weighing the benefits.
- Alcohol: Limit or avoid alcohol consumption as it may increase dizziness and drowsiness.
- Driving and machinery: The medication can contribute to dizziness and sudden episodes of sleep disorders. Therefore, the patient needs to exercise caution when driving or operating heavy machines at home.
- Drug interactions: Syndopa CR 50/200mg may interact with certain medications, including antihypertensive agents, antipsychotic drugs, iron supplements, and other anti-nausea medications. Be sure to inform your healthcare professional about your ongoing treatment. Like all pharmaceutical agents, the Levodopa/Carbidopa combination can cause adverse effects, although not everyone gets them.
Side effects of th Syndopa CR 200mg
Commonly reported side effects are nausea, vomiting, loss of appetite, headache, insomnia, vivid dreams, and dry mouth.
Moderate side effects of carbidopa and Levodopa include confusion, hallucinations, mood changes (depression, anxiety), involuntary movements (jerking, dyskinesia, writhing or twitching), irregular heartbeat or palpitations, and fluctuations in motor response.
Rare but serious side effects include:
- Sudden sleep attacks.
- Gastrointestinal bleeding (vomiting blood, black stools)
- Severe allergic reaction (itching rash, swelling, trouble breathing)
- Worsening of glaucoma (blurred vision, eye pain)
- Signs of liver problems (yellowing of eyes, dark urine)
- Malignant melanoma. Skin cancer is higher in long-term users. Regular skin monitoring is necessary.
To avoid side effects, Syndopa CR 50/200mg should be used strictly under the guidance of a healthcare professional, with regular monitoring for side effects and drug interactions.
How to use?
Administration methods of the Syndopa cr 50 200 mg
The dosing is strictly recommended by a healthcare professional based on the severity of symptoms, age, and prior response to Parkinson’s medication. Typically, the tablets are taken 1 to 3 times daily, but timings and quantity vary among patients. Swallow the tablet whole with a glass of water. Avoid chewing or crushing the tablet, as this could affect the controlled-release mechanism. It is generally recommended to take this medication with meals to minimise gastrointestinal side effects. However, protein-rich foods (such as meat, milk, and beans) may reduce the absorption of the drug; therefore, it is essential to adjust the timing accordingly. Parkinson’s disease requires long-term treatment. Sudden discontinuation may abruptly withdraw, may worsen symptoms or trigger neuroleptic malignant syndrome (a rare but serious reaction).
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