Tacroz 0.1%
Available Dosages
| SKU | 1043 |
|---|---|
| Generic For | Protopic |
| Strength | 0.1% (10 gm) |
| Manufacturer | Glenmark |
| Active Ingredient | Tacrolimus |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 1 Tube/s | US$ 13.51 | US$ 13.51 | |||
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| 3 Tube/s | US$ 13.51 | US$ 40.54 | |||
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| 6 Tube/s | US$ 13.51 | US$ 81.08 | |||
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Tacroz 0.1% (Tacrolimus) – Affordable Protopic Alternative
Tacroz .1 is an ointment prescribed for the treatment of eczema. It is an ointment used for topical application. It is an immunomodulatory medicine, which changes the immune system in some way. The active pharmaceutical ingredient of the medicine is Tacrolimus, which belongs to the class of medicines known as topical calcineurin inhibitors. It is for those individuals who do not have a weakened immune system. It is formulated for adults and children age two years or older.
What is Tacroz .1% used for?
Tacroz 0.1% is useful for the short-term relief of eczema flare-ups, and if required, the medicine may be repeated with breaks in between. It is considered when topical corticosteroids have not been effective
What does Tacroz contain?
Tacroz contains 0.1% of the active ingredient Tacrolimus. Each tube of Tacrolimus ointment contains 0.1% of the beneficial ingredient.
What medications interact with Tacroz?
- Immunosuppressive medicines such as azathioprine or ciclosporin should not be used in combination with Tacroz.
- Patients are advised not to receive light treatment such as PUVA or other UV light treatment during Tacrolimus treatment.
- There is a possibility that the use the following medications may raise the level of Tacrolimus in the blood if absorbed into the blood stream. These drugs should be used carefully in people using Tacroz ointment, especially in individuals with widespread eczema:
- Erythromycin
- Ketoconazole
- Diltiazem
- Itraconazole
When should Tacroz not be used?
- Tacroz should not be applied to children younger than two years of age.
- It is not suitable for patients who are allergic to the medicine or its ingredients.
Inform your physician before using the medicine:
- If you are pregnant or planning to conceive
- If receiving any form of light therapy on your skin
- If using any other topical agent
How should tacroz 0.1 ointment be taken?
Tacroz ointment should be applied as prescribed by the physician. It is meant to be applied to areas of skin that have eczema. A patient is supposed to use this topical medicine for short periods, and if required, Tacroz may be repeated with breaks in between.
Immediately, the treatment should be stopped when the signs and symptoms of eczema, such as redness, itching, and rash, or as directed by your physician.
The advice of a physician should be followed by every patient if symptoms of eczema return after finishing the treatment.
While applying the ointment, keep the following things in mind:
- Make sure that you rinse your hands before applying the topical agent.
- A thin layer should be applied two times a day to affected areas.
- A pea size amount of medicine is sufficient to control the signs and symptoms of eczema.
- Bathing, showering, or swimming is prohibited just after applying for the medicine as this could wash off the medicine.
- Avoid using a moisturizer with Tacroz ointment without first checking with your physician.
- It is important to inform the physician if the symptoms get worse with Tacroz ointment, or you get an infection on your skin. Also, if your symptoms do not improve after a period of six weeks. Sometimes other skin conditions can look like eczema.
How long should you take tacroz 0.1 ointment?
Patients are instructed to apply the ointment at the same time daily. Do not stop applying for the medicine without first checking with your physician because sudden discontinuation of the medicine may cause delay the results.
Missed dose of Tacroz
Do not double up the application just because you missed a dose. If you forget to apply, use it as soon as possible up to 8 hours before the next scheduled dose.
What are the side effects of tacroz 0.1 ointment?
The side effects of medicines can affect individuals in different ways. The following are some unwanted effects associated with the medicine:
- Itching at the site of application
- Burning sensation at the application site
- Facial flushing or skin irritation after consuming alcohol
- Infection and inflammation of the hair follicles
- Rash, irritation, redness at the application site
- Sensation of warmth, needles, and pins, or pain at the application site
- Herpes simplex infections such as eczema herpecticum
What is Tacroz 0.1% ointment used for?
Tacroz 0.1% contains the higher-strength tacrolimus ointment, approved for moderate to severe atopic dermatitis in adults aged 16 years and older. The 0.1% concentration provides stronger calcineurin inhibition than the 0.03% formulation, making it suitable for adults with more resistant or extensive eczema that hasn't responded to lower-strength options or topical steroids. It is particularly valued for managing eczema on the face, neck, and skin folds where high-potency steroids are not recommended.
How is Tacroz 0.1% more effective than 0.03%?
The 0.1% formulation delivers three times more tacrolimus per gram than the 0.03% ointment, achieving higher skin concentrations and more complete local calcineurin inhibition. Clinical studies demonstrate greater reduction in eczema severity scores with 0.1% compared to 0.03%, particularly in adults with moderate to severe disease. The 0.1% strength is reserved for adults due to the larger body surface area-to-weight ratio in adults, which reduces the risk of systemic absorption per unit dose.
How should Tacroz 0.1% be applied correctly?
Apply Tacroz 0.1% in a thin layer to all affected skin areas twice daily. Gently smooth in until absorbed. Avoid eyes and mucous membranes. Wash hands thoroughly after use unless treating hand eczema. Do not apply to infected skin — treat infections first. Minimise sun exposure on treated areas and use broad-spectrum sunscreen during treatment. Once eczema clears, switch to twice-weekly application on previously affected areas to prevent relapse.
How long before Tacroz 0.1% produces significant eczema improvement?
Adults using Tacroz 0.1% typically notice improvement in itching within 3–5 days. Visible reduction in erythema, scaling, and skin lesions is usually apparent within 1–2 weeks of consistent twice-daily use. Severe eczema may take 3–4 weeks to show maximum benefit. Response rates are higher with 0.1% than 0.03% in adults — approximately 40–50% of patients achieve clear or almost clear skin at 12 weeks of twice-daily use in clinical trials.
Is Tacroz 0.1% safe for long-term use on facial eczema?
Tacroz 0.1% is one of the few effective long-term options for facial eczema in adults, as it does not cause the skin atrophy, telangiectasia, or hypothalamic-pituitary-adrenal axis suppression associated with long-term topical steroids on the face. It is widely used in maintenance therapy — twice-weekly application to previously affected facial areas — to prevent eczema relapse. Regular dermatological review is advisable for patients using it for more than 12 months.
Can Tacroz 0.1% worsen skin infections?
Yes — tacrolimus suppresses local immune responses in the skin. This can impair the skin's defences against bacterial, fungal, and viral infections. Herpes simplex virus (cold sores) and molluscum contagiosum infections can spread in tacrolimus-treated areas. Always treat active skin infections before applying Tacroz 0.1%. If you develop signs of a skin infection — increased redness, crusting, pustules, or vesicles — stop using the ointment and consult your dermatologist.
How does Tacroz 0.1% compare to mometasone furoate 0.1% cream for eczema?
Tacroz 0.1% (tacrolimus) and mometasone furoate 0.1% cream are both effective for moderate-severe eczema. Mometasone is a mid-potency corticosteroid with faster initial response but risks of skin atrophy with continuous use. Tacroz 0.1% does not cause atrophy and is superior for long-term or maintenance therapy, particularly on the face and skin folds. Many dermatologists combine them: corticosteroids for acute flares, tacrolimus for maintenance.
Is Tacroz 0.1% equivalent to Protopic 0.1%?
Yes. Tacroz 0.1% contains the same active ingredient — tacrolimus 0.1% in an ointment base — as branded Protopic 0.1%. Both are indicated for moderate to severe atopic dermatitis in adults and have identical efficacy and safety profiles. Tacroz 0.1% is a generic formulation providing the same clinical benefit as Protopic at a significantly lower cost.
Can I order Tacroz 0.1% from PremiumRxDrugs with worldwide shipping?
Yes. PremiumRxDrugs.com ships Tacroz 0.1% internationally to the USA, UK, Australia, and many other countries. Our licensed pharmacy model, over a decade of trusted service, genuine manufacturer-verified medicines, and free worldwide shipping on qualifying orders make us a reliable choice for patients requiring ongoing non-steroidal eczema management.
What side effects does Tacroz 0.1% commonly cause?
Tacroz 0.1% frequently causes transient burning, stinging, and erythema at application sites during the first 1–2 weeks of use — these are more common at the 0.1% strength than at 0.03%. Pruritus may temporarily worsen before improving. Acne, folliculitis, and skin infections are occasionally reported. The burning sensation typically diminishes significantly as the skin heals. Persistent side effects warrant dermatologist assessment.
Who should not use Tacroz 0.1% ointment?
Tacroz 0.1% is not approved for children under 16 years (the 0.03% strength is used in those aged 2–15). It should not be used on infected skin, under occlusion, or near eyes and mucous membranes. Patients with Netherton syndrome, skin malignancy, or immunodeficiency disorders should avoid topical tacrolimus. The FDA black box warning notes a theoretical malignancy risk (lymphoma, skin cancer) — minimise sun exposure on treated areas and schedule regular dermatological reviews.
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