Tropicacyl - Eye drop of 5 ml

Tropicacyl - Eye drop  of 5 ml

Tropicacyl is an antimuscarinic ophthalmic formulation used to produce mydriasis (dilated pupils) and cycloplegia (paralysis of the ciliary muscles resulting in pupil dilation and paralysis of accommodation). It contains the active ingredient Tropicamide and has anticholinergic properties that block the responses of the sphincter muscle of the iris and the ciliary muscles to cholinergic stimulation, dilating the pupil. The ophthalmic agent also Paralyzes accommodation.   

How to use (infographics and instructions)

One to two drops are instilled 15 to 20 minutes before the eye examination to produce mydriasis. To poduce cycloplegi. One to two drop is required, repeated after five minutes. A further drop may be required to prolong the effect after 20 to 30 minutes. Those with heavily pigmented irides may require higher strength or more doses. Mydriasis will reverse with time, typically in 4 to 8 hours. However, in some cases, complete recovery may take up to 24 hours.      

Precautions (warning, allergy, things to remember)

Tropicacyl should not be used in patients hypersensitive to Tropicamide or other components in the formulation. The product is for topical use only and not for injection. Tropicamide is not recommended for patients with narrow-angle glaucoma since it may increase intraocular pressure and trigger an acute attack. The ophthalmic preparation should be used with caution in conditions characterized by tachycardia, such as heart failure and thyrotoxicosis, and in cardiac surgery, where it may further increase the heart rate. Care should be taken in patients with acute myocardial infarction as ischemia and infarction may worsen. Tropicacyl eye drops may significantly increase intraocular pressure.

Tropicamide has been reported to be inadequate for cycloplegia in children. Avoid the use in children. Cycloplegics and mydriatics should be used cautiously in the elderly and others with increased eye pressure. The ophthalmic formulation may cause transient blurring of vision on application. Patients are instructed to avoid driving or operating hazardous machinery until their vision is clear. Patients may develop light sensitivity and should protect their eyes from bright illumination during dilation.

The effects of antimuscarinic agents such as Tropicacyl may be enhanced by the concomitant use of other drugs with antimuscarinic properties. Prolonged cycloplegic and mydriatic effects of Tropicamide were reported.  

Tropicamide can interfere with the antihypertensive action of pilocarpine, carbachol, or ophthalmic cholinesterase inhibitors.

Side effects of Tropicacyl- Eye drop of 5 ml

Ocular side effects, including blurred vision, photophobia, transient stinging, and superficial punctate keratitis, have been reported using Tropicamide. Increased pressure has been reported following the use of mydriatics.

Non-ocular side effects include headache, tachycardia, dryness of the mouth, nausea, vomiting, allergic reactions, pallor, central nervous system disturbances, and muscle rigidity have been reported with the use of Tropicamide. Behavioural problems, psychotic reactions, and vasomotor or cardiorespiratory collapse in paediatric patients have been reported using anticholinergic drugs.