Unicontin Controlled Release Tablets 400mg
Available Dosages
| SKU | 1103 |
|---|---|
| Generic For | Uniphyl |
| Strength | 400mg |
| Active Ingredient | Theophylline |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 30 Tablet/s | US$ 0.67 | US$ 20.00 | |||
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| 60 Tablet/s | US$ 0.50 | US$ 30.0025%US$ 40.00 | |||
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| 90 Tablet/s | US$ 0.44 | US$ 40.0033%US$ 60.00 | |||
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Unicontin CR 400mg (Theophylline) – Affordable Uniphyl Alternative
Unicontin CR 400 mg tablets, is prescribed to treat airway blockage that may occur due to asthma and other long-term breathing problems like bronchitis, emphysema, or COPD. It contains the active substance Theophylline, known as a xanthine derivative, which effectively relaxes the muscles of air passages in the lungs. This causes the passages to widen, making it easier for you to breathe. Unicontin helps to relieve symptoms such as shortness of breath, chest tightness, coughing, and wheezing and helps you carry out your daily activities more easily. Moreover, this oral medicine makes the diaphragm (the muscle between your lungs and stomach that helps you breathe) stronger and the airways resistant to irritants.
Precautions Unicontin CR 400mg
Ensure that your doctor knows about your:
- Pregnancy status, whether you are pregnant or are planning to conceive.
- List medications you use, including all prescribed, non-prescribed, and herbal products.
- List of allergies to any food items or medication you may have.
- Infection, ulcer, or fever condition. Avoid smoking as this may interfere with the absorption of the medicine as well as worsen the condition for which it is prescribed. So, if you smoke or take marijuana when Unicontin is prescribed, the drug’s dosage may need to be adjusted to prevent toxicity.
Certain foods can affect the function of Theophylline; thus, before you begin treatment, discuss with your doctor any food you should avoid.
Side effects Unicontin CR 400mg
Common side effects of this medicine include convulsions, sleeplessness, allergic skin reaction, swelling of ankles or feet, yellow-coloured eyes or skin, and increased urination frequency. Report acute insomnia or restlessness, rapid heartbeat, chest pain, muscle tremors, acute headache, cramping, blackened stool, abdominal pain, or worsening of respiratory condition to your health care specialist. If you experience any other side effects, contact your doctor immediately. For best results, follow the prescribed instructions carefully. Do not exceed the recommended dose.
How to use Unicontin 400 mg CR
Take a Unicontin Controlled Release 400mg an hour or two hours before meals with a glass of water. Do not chew or crush the tablet. Avoid dietary stimulants such as tea, caffeine, chocolate, or colas that may increase adverse side effects. Maintain adequate hydration during the treatment. You may develop nausea, vomiting, or loss of appetite. Unicontin is safe and effective. It usually begins to work within a few minutes, and the effects may last several hours. The medicine does not work immediately or prevent a breathing problem that has already started; hence, always carry your prescribed inhaler with you for an emergency.
What is Theophylline and what condition does it treat?
Theophylline is a bronchodilator medication used primarily to treat respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and emphysema. Unicontin CR 400mg is a controlled-release formulation containing theophylline as its active ingredient. This airway-opening medicine helps prevent and manage breathing difficulties, wheezing, chest tightness, and shortness of breath. By relaxing the muscles around the airways, this bronchodilator tablet allows easier airflow into the lungs. The controlled-release design of Unicontin CR provides sustained therapeutic effects, making it particularly useful for managing chronic respiratory symptoms and preventing nighttime breathing problems.
How does Theophylline work in the body?
Theophylline works through multiple mechanisms to improve breathing. This bronchodilator medicine primarily relaxes smooth muscle tissue in the airways, widening the bronchial passages and making breathing easier. Unicontin CR 400mg also reduces inflammation in the respiratory tract and decreases the lungs' sensitivity to irritants and allergens. Additionally, theophylline strengthens the diaphragm muscle, improving respiratory function. It belongs to a class of medications called methylxanthines, which also stimulate the central nervous system and heart mildly. The controlled-release formulation ensures steady blood levels of the active ingredient throughout the day, providing consistent airway relief for asthma and COPD patients.
How long does Unicontin CR 400mg take to work?
Unicontin CR 400mg begins releasing theophylline gradually after ingestion, with noticeable effects typically starting within 1 to 2 hours. However, because this is a controlled-release bronchodilator, it reaches peak effectiveness around 4 to 7 hours after administration. The full therapeutic benefit for asthma or COPD management usually develops after several days of consistent use, once steady blood levels are established. This extended-release respiratory medicine is designed for maintenance treatment rather than quick relief of acute breathing episodes. For sudden asthma attacks or immediate breathlessness, a fast-acting inhaler is more appropriate. The sustained-release design provides all-day airway protection with twice-daily dosing.
When and how should I take Unicontin CR 400mg?
Unicontin CR 400mg is typically taken twice daily, approximately 12 hours apart, to maintain consistent theophylline levels in your bloodstream. Swallow the tablet whole with water—do not crush, chew, or split it, as this destroys the controlled-release mechanism and can cause dangerous side effects. This bronchodilator can be taken with or without food, though taking it consistently the same way helps maintain stable blood levels. Most patients find morning and evening dosing convenient for managing asthma or COPD symptoms. Your doctor will prescribe the exact timing based on your condition severity and other medications. Always follow your prescribed schedule precisely for optimal respiratory control.
Is Unicontin CR 400mg safe for long-term use?
Unicontin CR 400mg can be used safely for extended periods when properly monitored by healthcare professionals. Many asthma and COPD patients take theophylline-based bronchodilators for years as part of ongoing respiratory maintenance therapy. However, long-term use requires regular blood tests to ensure theophylline levels remain within the therapeutic range—too low means inadequate symptom control, while too high increases side effect risk. Your doctor will periodically review your treatment to ensure this controlled-release medicine continues working effectively. Factors like age, smoking status, liver function, and concurrent medications can affect how your body processes this airway treatment, making medical supervision essential for sustained use.
Can I take Unicontin CR 400mg with other medicines?
Theophylline in Unicontin CR 400mg can interact with numerous medications, making professional guidance essential before combining treatments. Antibiotics like erythromycin and ciprofloxacin, heart medications, seizure drugs, and even some ulcer treatments can alter theophylline blood levels significantly. Common bronchodilators and asthma inhalers are usually compatible, but stimulant medications may increase side effects. Herbal supplements like St. John's Wort also interact with this respiratory medicine. Even caffeine consumption can enhance theophylline's stimulant effects. Smoking and alcohol also impact how your body processes this COPD medication. Always provide your healthcare provider with a complete list of prescription drugs, over-the-counter products, and supplements you're taking.
How does Unicontin CR 400mg compare to similar medicines in its class?
Unicontin CR 400mg offers distinct advantages within the methylxanthine bronchodilator class. Compared to immediate-release theophylline formulations requiring three or four daily doses, this controlled-release tablet provides convenient twice-daily dosing with more stable blood levels and fewer peaks and troughs. Unlike short-acting beta-agonist inhalers that provide quick relief, Unicontin CR delivers sustained airway protection for asthma and COPD. While newer respiratory medications like leukotriene modifiers and long-acting inhalers exist, theophylline remains cost-effective and beneficial, especially when other treatments prove insufficient. The 400mg strength allows flexible dosing adjustments. Many respiratory specialists combine this bronchodilator with inhaled corticosteroids for comprehensive chronic airway disease management.
Is the generic Theophylline as effective as branded versions?
Generic theophylline formulations are equally effective as branded versions like Unicontin CR 400mg when manufactured to proper pharmaceutical standards. Both contain the identical active ingredient in the same controlled-release mechanism, providing equivalent bronchodilator effects for asthma and COPD treatment. Regulatory authorities in the USA, UK, Canada, and Australia require generic respiratory medicines to demonstrate bioequivalence—meaning they deliver theophylline to your bloodstream at the same rate and extent as the brand-name product. The primary difference lies in inactive ingredients and cost, with generics offering significant savings. Whether choosing branded or generic methylxanthine therapy, quality sourcing from licensed pharmacies ensures you receive authentic, effective airway medication.
Why do patients choose PremiumRxDrugs for Unicontin CR 400mg?
Patients consistently select PremiumRxDrugs for their Unicontin CR 400mg supply because of the pharmacy's comprehensive value proposition. Beyond competitive pricing on theophylline bronchodilators, customers appreciate accessing both branded and generic respiratory medications from one trusted source. The pharmacy's commitment to supplying only manufacturer-sourced, authentic asthma and COPD treatments provides peace of mind about medication quality. International patients value worldwide shipping with discreet packaging that protects privacy. The intuitive prescription management system simplifies refills for ongoing respiratory therapy. After serving customers reliably for more than ten years, PremiumRxDrugs has built a reputation for combining pharmaceutical expertise with customer-focused service, making chronic airway medication management more accessible and affordable globally.
What are the common side effects of Theophylline?
Common side effects of theophylline include nausea, headache, insomnia, restlessness, and increased urination. Some patients experience stomach upset, vomiting, or diarrhea when starting this bronchodilator medication. The stimulant properties of this methylxanthine can cause jitteriness, rapid heartbeat, or tremors, particularly at higher blood levels. Many side effects diminish as your body adjusts to the respiratory medicine. Taking controlled-release formulations with food may reduce gastrointestinal discomfort. Serious effects like irregular heartbeat, seizures, or persistent vomiting require immediate medical attention, though these typically occur only when blood levels become too high. Most asthma and COPD patients tolerate theophylline well when blood levels are properly monitored and maintained within the therapeutic range.
Who should avoid taking Theophylline?
Certain individuals should avoid theophylline or use it only under close medical supervision. People with uncontrolled seizure disorders, severe heart arrhythmias, or recent heart attacks face increased risks with this bronchodilator. Those with active peptic ulcers, hyperthyroidism, or severe liver disease may experience complications from this respiratory medication. Pregnant and breastfeeding women require careful evaluation, as this methylxanthine crosses into breast milk. Elderly patients often need lower doses due to slower medication clearance. Children require precise dosing calculations based on weight. Anyone with a history of theophylline toxicity should explore alternative asthma or COPD treatments. Your healthcare provider will assess your complete medical history before prescribing this airway medicine to ensure it's appropriate for your situation.




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