Acnesol Gel 1% (20gm)

$4.00 - $5.00

Available Dosages

SKU 254
Generic For Cleocin T
Strength 1% (20gm)
Manufacturer Systopic
Active Ingredient Clindamycin
Pack Size Qty Price Per Pill or Unit Price Cart
1 Tube/s US$ 5.00 US$ 5.00
3 Tube/s US$ 4.00 US$ 12.0020%US$ 15.00
6 Tube/s US$ 4.00 US$ 24.0020%US$ 30.00
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Acnesol Gel 1% (Clindamycin) – Affordable Cleocin T Alternative

Acnesol gel 1% contains Clindamycin, an antibiotic agent useful for treating several bacterial infections. It treats acne vulgaris, typically suppressing cutaneous Propionibacterium acnes (a gram-positive human skin commensal involved in acne's pathogenesis). Acnesol gel may also be used for other health conditions not mentioned on this page.

Acnesol gel is indicated for topical application in the treatment of acne vulgaris in patients 12 years of age and older. Acne vulgaris is characterised by areas of pimples, whiteheads, blackheads, and greasy skin and may result in scarring. It occurs when the skin pores become clogged with dead skin cells and sebum.

Clindamycin, a semisynthetic derivative of lincomycin, reveals potent activity against gram-negative and gram-positive bacterial infections. The drug inhibits bacterial protein synthesis, thereby stopping bacterial growth.

Precaution and warnings of Acnesol gel 1%

  • Concurrent use of topical medications containing alcohol should be avoided because they potentiate drying action on the skin. The solvent contained in some medicated soaps, abrasive cleansers, or cosmetics is alcoholic. They may cause a cumulative irritant effect in individuals undergoing Acnesol 1% gel treatment.
  • Topical acne medications containing benzoyl peroxide, tretinoin, salicylic acid, or resorcinol may sensitize the skin to unwanted reactions. Concurrent use of Acnesol 1% gel and these abrasive agents should be cautiously treated in combination therapy.
  • Keep a list of all your topical agents and give it to your physician. Also, do not start new prescriptions, herbal products, over-the-counter medicines, and dietary supplements without telling your physician. 

Side effects of Acnesol gel?

Some of the common side effects of Acnesol 1% gel may include:

  • Burning
  • Itching
  • Dryness
  • Skin peeling
  • Oily skin

If these side effects persist longer, stop applying for the medicine and seek immediate medical help. Other side effects not mentioned above may occur in some patients. Inform your physician if you observe anything that is making you feel unwell.

How to use Acnesol 1% ?

  • Acnesol 1% gel is for external use only and is applied directly to the skin. Before applying the gel, wash your face with a mild soap and lukewarm water. Apply a thin layer directly to each acne lesion or to affected areas. Rub it well into the skin. Don't forget to wash your hands properly after the application.

 

  • The topical medication is usually applied to the affected areas twice daily. The frequency will depend upon the severity of the condition and skin tolerance, but it should not be more than twice a day. Acne treatment should be individualized according to the type of lesions predominate and the response to treatment.

 

  • Don't let this topical medication contact the delicate parts of your face like eyes, nose, or lips. Wash them thoroughly with water if they are exposed to the medication accidentally.

 

  • Patients treated with Acnesol 1% gel acne treatment may use cosmetics, but the affected area to be treated should be cleansed thoroughly before the medicine is applied.
  • Don't apply this formulation in more than the prescribed quantity; doing this can cause skin irritation rather than treating it early.

 

  • A decrease in inflammatory lesions should be noticed after two to six weeks, but more than eight weeks of treatment may be required before any definite beneficial effects are seen. Call your physician if your condition still does not improve after this time.

 

  • Always remember to use Acnesol 1% gel on time. If you miss a dose, use it as soon as you remember.

 

  • The contents of Acnesol 1% gel are flammable, so keep the medicine away from heat and flame. Store the gel at room temperature, and do not freeze it. Also, keep it out of the reach of children and away from pets.
Acnesol Gel 1% (20gm)

What is Acnesol 1% Gel used for?

Acnesol 1% Gel contains clindamycin phosphate 1% — a topical lincosamide antibiotic for acne vulgaris. It inhibits bacterial protein synthesis in P. acnes by binding to the 50S ribosomal subunit, reducing bacterial counts on skin and in follicles, and decreasing inflammatory mediator production. Indicated for mild-to-moderate inflammatory acne (papules, pustules) — particularly effective against the inflammatory component of acne. Like all topical antibiotics, Acnesol 1% should be combined with benzoyl peroxide to prevent antibiotic resistance development. It does not address comedone formation — combination with a topical retinoid provides comprehensive acne management targeting both bacterial and comedonal pathology.

How should Acnesol 1% Gel be applied for acne?

Apply Acnesol 1% Gel to the entire acne-prone area (not just individual spots) once or twice daily after gentle cleansing and drying. Use a thin layer — rub in gently. Application time: can be used morning or evening; if combining with tretinoin (evening) + benzoyl peroxide (morning), topical clindamycin is typically applied in the morning or evening depending on which simplifies the overall routine. Wash hands after application. Avoid eyes, mucous membranes, and oral cavity. Do not use near open wounds. Consistent daily use for the minimum recommended course (3–6 months maximum) is important for both efficacy and limiting resistance risk.

What is the risk of antibiotic resistance with Acnesol 1% Gel?

Clindamycin-resistant P. acnes strains have increased significantly since topical antibiotics were introduced in acne treatment — resistance rates now exceed 50% in some regions. Risk factors for resistance: topical antibiotic monotherapy (no benzoyl peroxide co-use); prolonged use (>3–6 months); switching between different antibiotics without adequate clearance intervals. To minimise resistance: always combine Acnesol 1% with benzoyl peroxide (morning) — benzoyl peroxide kills resistant P. acnes strains regardless of clindamycin resistance; limit topical antibiotic use to 3–6 months; do not use as indefinite maintenance therapy; after stopping, maintain with tretinoin + benzoyl peroxide rather than antibiotic. Clindamycin and erythromycin should not be used simultaneously — cross-resistance occurs.

What drug interactions apply to Acnesol 1% Gel?

Systemic absorption of topical clindamycin 1% gel is minimal — significant systemic interactions are not expected. Local interactions: do not use Acnesol alongside topical erythromycin — clindamycin and erythromycin antagonise each other (clindamycin competitively blocks the same ribosomal binding site that erythromycin targets, reducing both drugs' antibacterial activity). Benzoyl peroxide is compatible — apply at different times of day; if applying both in the morning, apply clindamycin first and allow absorption before benzoyl peroxide (or use a pre-formulated combination). Tretinoin/retinoids: compatible — use tretinoin at night and clindamycin in the morning. Avoid applying alongside irritating agents (alcohol-based toners, abrasive scrubs) — cumulative skin irritation.

How does Acnesol 1% Gel compare to oral antibiotics for acne?

Topical clindamycin 1% (Acnesol) vs. oral clindamycin/doxycycline for acne: topical use delivers high local drug concentration directly to the follicle with minimal systemic exposure — superior concentration at the site of action. Oral antibiotic advantages: superior for severe, widespread, or truncal acne (where topical coverage is impractical); faster onset for severe inflammatory acne. Topical advantages: avoids systemic GI side effects (oral clindamycin can cause antibiotic-associated colitis — a potentially serious complication); no systemic antibiotic resistance concerns beyond the skin; suitable for mild-moderate localised acne. Current guidelines: use topical antibiotics for mild-moderate inflammatory facial acne; reserve oral antibiotics for moderate-severe, truncal, or topical-refractory acne.

Is Acnesol 1% equivalent to Cleocin T or Dalacin T?

Yes. Acnesol 1% Gel and branded Cleocin T 1% Gel (USA) / Dalacin T 1% Gel (Europe) all contain clindamycin phosphate 1% in equivalent gel formulations. Acnesol is the generic alternative providing the same topical antibiotic acne treatment at significantly lower cost. PremiumRxDrugs.com stocks authentic manufacturer-sourced Acnesol 1% Gel verified for quality and bioequivalence.

Can I order Acnesol 1% Gel from PremiumRxDrugs for international delivery?

Yes. PremiumRxDrugs.com ships Acnesol 1% Gel to the USA, UK, Australia, and many other countries. Our genuine manufacturer-verified topical antibiotic products, competitive pricing, and free worldwide shipping on qualifying orders make us a reliable international source for clindamycin gel acne therapy.

What side effects does Acnesol 1% Gel cause?

Acnesol 1% Gel is generally very well tolerated. Local effects: mild dryness; occasional burning or stinging on application (transient); rarely, mild skin peeling. Folliculitis (inflammation of hair follicles — acneiform reaction) is rare but possible. Contact dermatitis (allergy to clindamycin) is uncommon. Systemic effects from topical application: very low absorption — oral clindamycin's GI effects (diarrhoea, antibiotic-associated colitis including C. difficile colitis) are not expected from topical use; however, the FDA product information notes this theoretical risk with extensive application — do not apply topical clindamycin to large body areas under occlusion long-term. If GI symptoms develop during topical use, consult a doctor.

Is Acnesol 1% Gel safe in pregnancy?

Topical clindamycin 1% gel is FDA Category B for pregnancy — considered safe for topical use during pregnancy. Systemic absorption from topical application is minimal, and there is no established teratogenicity or adverse pregnancy outcome associated with topical clindamycin. It is listed as an acceptable topical antibiotic for acne management during pregnancy in major dermatology guidelines — combined with azelaic acid for comprehensive acne management. Oral clindamycin has different considerations in pregnancy (Category B but GI risks are more relevant) — topical use avoids these concerns. Use for the minimum effective duration; consult your obstetrician if starting any new medication during pregnancy.

What are the signs of topical clindamycin not working for acne?

Signs that Acnesol 1% topical clindamycin is not adequately controlling acne: no reduction in inflammatory lesion count (papules, pustules) after 8–12 weeks of consistent twice-daily use; new lesion formation continuing at the same rate despite treatment; predominantly comedonal acne that is not responding (clindamycin does not address comedones — a retinoid is needed for comedonal acne). Non-response causes: clindamycin-resistant P. acnes (increasingly common); predominantly non-inflammatory/comedonal acne where antibiotics have limited benefit; inconsistent use; additional acne triggers (hormonal, dietary) overwhelming treatment. If inadequate response at 12 weeks: add benzoyl peroxide, add a topical retinoid, or consider oral antibiotic therapy under medical guidance.

How should Acnesol 1% Gel be stored?

Store Acnesol 1% Gel at room temperature (15–30°C) away from direct sunlight and heat. Do not freeze. Keep the tube tightly capped between uses to prevent evaporation of the alcohol vehicle and contamination. Keep out of reach of children. Check expiry date before use. An opened tube should be used within 12 months per the product label. If the gel develops an unusual colour, texture, or odour, replace with a fresh tube. The gel vehicle is typically alcohol-based — keep away from open flames. Store in the original packaging to protect from light degradation.

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