Flixotide Discus 250 mcg
Available Dosages
| SKU | 446 |
|---|---|
| Generic For | Flovent |
| Strength | 250 mcg |
| Manufacturer | GSK, France |
| Active Ingredient | Fluticasone Propionate |
Out Of Stock
Flixotide Discus 250 mcg – Affordable Flovent Alternative
Flixotide Diskus 250 mcg (Fluticasone Propionate)
Flixotide Diskus is a prescribed medication for the Asthma cure. It is an inhaled prescription used to reduce the symptoms and worsening. of asthma. Flixotide Diskus cease the inflammatory process, which results in swelling of lungs, and also stops the symptoms of asthma, including wheezing, cough tightness of the chest and shortness of breath. It is prescribed for adults and children above four years of age.
What is Flixotide Diskus used for?
Flixotide Diskus contains active ingredient Fluticasone propionate. It is a corticosteroid which is chemically synthesized and used to reduce the swelling and irritation in the lungs. This medication is also prescribed to cure Asthma and Chronic Obstructive Pulmonary Disease (COPD). This medication is not prescribed to treat the acute attacks of bronchospasm.
How does Flixotide Diskus work?
The main chief ingredient of Flixotide Diskus is Fluticasone propionate. This Fluticasone belongs to the category of drugs known as corticosteroid. This corticosteroid has anti-inflammatory activity that inhibits the generation of inflammatory chemicals released in the airways. These chemicals are called inflammatory mediators. The reason behind asthma is inflammation due to which airways become narrow. It exerts its effects directly on the bronchioles to reduce inflammatory reactions, which helps to reduce the symptoms of asthma caused by swollen and inflamed airways, like wheezing, cough, tightness of the chest and shortness of breath.
What are the different doses of Flixotide Diskus?
Buy Flixotide Diskus at a quite affordable price. Flixotide Diskus is available to order online from premiumrxdrugs.com.
What does Flixotide Diskus contain?
Flixotide Diskus is a molded plastic device that contains a foil strip with regularly placed blisters each containing a mixture of 100 mcg of Fluticasone propionate.
What are the side effects of Flixotide Diskus?
The common side effects of Flixotide Diskus 100 mcg include:
The most commonly reported side effects are: Pneumonia, hypersensitivity reactions; includes Itching or rashes, swelling in the facial region, painful breathing, increased blood sugar level, Paradoxical bronchospasm and anaphylactic reactions.
What medications interact with Flixotide Diskus?
The medications which interfere with the working of Flixotide Diskus are mentioned as; Erythromycin, Neomycin, Ritonavir, Ketoconazole, Fluconazole, Itraconazole, Voriconazole, Amoxicillin, and Delavirdine.
When should Flixotide Diskus not be used?
- Flixotide Diskus 100 mcg should not be used if you are allergic proteins. Ask your physician for more information
- Do not use the Diskus if you are allergic to Fluticasone propionate or any other ingredients present in Flixotide Diskus
- It is not recommended for use in children younger than four years of age
How should Flixotide Diskus be used?
- First you have to open your Flixotide Diskus. Hold the outer case with one hand and press the lid of thumb grip with the other hand.
- Place your Diskus towards your mouth by sliding the lever.
- Your device is primed and ready to use.
- Exhale out with force.
- Then inhale the medicament smoothly or deeply.
- Hold your breath for seconds.
- Close your Diskus by sliding the lever.
- Rinse your mouth after use.
How long should you use Flixotide Diskus?
It may take 24-48 hours or longer after you start taking Flixotide Diskus for your asthma symptoms to get better.
Missed dose of Flixotide Diskus
If you miss a dose of Flixotide Diskus, just leave that dose. Take your next dose at your normal dosing schedule. Do not consume two doses at the same time.
How should Flixotide Diskus be stored?
- Store Flixotide Diskus 100 mcg at room temperature
- Keep it in a dry place away from direct light and heat
- Store the Diskus in the opened foil pouch unless you open it for use
- Keep all your medicines out o the reach of children and pets
What is Flixotide Discus 250mcg used for?
Flixotide Discus 250mcg is a dry powder inhaler containing fluticasone propionate 250mcg per blister dose in an Accuhaler (Discus) device. It is used as a regular maintenance inhaled corticosteroid (ICS) for moderate-to-severe persistent asthma in adults and adolescents. At 500mcg/day (2 doses twice daily), it provides medium-high ICS dosing. It reduces airway inflammation, prevents asthma exacerbations, and decreases reliance on short-acting relievers when used consistently.
How does fluticasone 250mcg improve asthma control?
Fluticasone 250mcg per dose provides approximately 500mcg daily when used as 1 blister twice daily — placing it in the medium-high ICS dose range. At this dose, it suppresses airway eosinophilia, reduces submucosal oedema, stabilises mast cells, and decreases airway hyperresponsiveness more effectively than lower-dose ICS. Measurable improvements in FEV1, peak flow, and symptom scores typically occur within 2–4 weeks of consistent daily use, with maximum benefit at 8–12 weeks.
How should Flixotide Discus 250mcg be used?
Slide open the Accuhaler (Discus) device. Breathe out fully away from the mouthpiece. Place lips around the mouthpiece and inhale quickly and deeply. Remove inhaler and hold breath for 10 seconds. Close the device after use. Standard adult dose: 1 blister (250mcg) twice daily. Rinse mouth with water and spit after each dose. Keep the Discus in its protective foil pouch. Check the dose counter to know when to reorder. Do not breathe into the Discus.
When should I step up to Flixotide Discus 250mcg from lower ICS doses?
Stepping up to 250mcg fluticasone twice daily is recommended when low-dose ICS (100mcg twice daily) does not achieve adequate asthma control — evidenced by persistent nocturnal symptoms, frequent rescue inhaler use (>2 times/week), or reduced peak flow variability. If 250mcg twice daily alone remains inadequate, adding a LABA (salmeterol) — as a combination inhaler — is preferred over further increasing the ICS dose, as the LABA provides greater additional benefit than dose escalation alone.
Is Flixotide Discus 250mcg safe for long-term use?
Long-term use at 250mcg twice daily (500mcg/day total) is appropriate for patients requiring medium-high ICS maintenance. At this dose, systemic effects are possible with prolonged use — skin bruising, occasional mild adrenal suppression. Annual DXA bone density monitoring is recommended for patients on high-dose ICS for several years. Children on 250mcg should have height monitored 6-monthly. The aim is always to step down to the lowest dose that maintains full asthma control.
What drug interactions affect fluticasone from the Discus inhaler?
The most important interactions are with potent CYP3A4 inhibitors — ritonavir, cobicistat, itraconazole, ketoconazole. These drugs markedly increase systemic fluticasone exposure, potentially causing Cushing's syndrome and adrenal suppression even at inhaled doses. If you are taking HIV medications or antifungals, inform your respiratory physician — alternative ICS with less CYP3A4-dependent metabolism (e.g., budesonide, beclomethasone) may be preferred. Other corticosteroids (oral, nasal, topical) used concurrently add to systemic steroid burden.
How does Flixotide Discus 250mcg compare to Pulmicort Turbohaler 200mcg?
Flixotide (fluticasone propionate) 250mcg and Pulmicort (budesonide) 200mcg are both medium-dose ICS in DPI format. Fluticasone is approximately 2× more potent per microgram than budesonide, so 250mcg fluticasone is roughly equivalent to 400–500mcg budesonide. Both effectively control asthma. Fluticasone has lower systemic bioavailability from the swallowed fraction; budesonide has a higher inhaled lung fraction. Clinical differences are minor; choice depends on device preference and cost.
Is Flixotide Discus 250mcg the same as Flovent Diskus 250mcg?
Yes. Flixotide Discus 250mcg and Flovent Diskus 250mcg (USA brand) both contain fluticasone propionate 250mcg per actuation in an Accuhaler/Diskus DPI device. They are the same product marketed under different names in different countries. Both deliver identical doses with the same efficacy and safety profile. Flixotide is the more widely recognised name globally, while Flovent is the US market brand.
Where can I order Flixotide Discus 250mcg online?
Flixotide Discus 250mcg is available at PremiumRxDrugs.com, shipping to the USA, UK, Australia, and worldwide. Our licensed pharmacy provides authentic manufacturer-sourced fluticasone Discus inhalers at prices lower than branded alternatives. Free shipping on qualifying orders and discreet worldwide delivery support consistent daily asthma management.
Can I buy Flixotide Discus 250mcg from PremiumRxDrugs for delivery to Australia?
Yes. PremiumRxDrugs.com ships Flixotide Discus 250mcg and other respiratory medications to Australia, the USA, UK, and many other countries. Our genuine manufacturer-verified inhalers, competitive pricing, and free worldwide shipping on qualifying orders make us a reliable international pharmacy for patients managing moderate-to-severe asthma.
What side effects are associated with Flixotide Discus 250mcg?
Oral thrush (candidiasis) and hoarseness are the most common side effects — rinsing mouth after each dose reduces risk significantly. Throat irritation and cough are occasionally reported. At 500mcg/day, systemic steroid effects are possible with prolonged use: skin bruising, reduced bone density, and in rare cases, HPA axis suppression. Adrenal crisis has been reported in patients switching from high-dose ICS to lower doses or during acute illness — always taper rather than stop abruptly.
What precautions apply to Flixotide Discus 250mcg users?
Rinse and gargle after every dose. Do not use as a rescue inhaler. Keep a SABA reliever (salbutamol) available. Be cautious with CYP3A4 inhibitors (antifungals, certain HIV medications) which increase systemic fluticasone levels. Monitor bone density with annual DXA if on high-dose ICS for >2 years. Carry a steroid card if on high-dose ICS. Never stop abruptly — taper under medical supervision. Inform surgeons of long-term ICS use before any procedure.
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