SKU	512
Generic For	Hisone
Strength	5mg
Manufacturer	Samarth Life Science.
Active Ingredient	Hydrocortisone

Product Description

Hisone 5mg (Hydrocortisone)

Hisone 5mg tablets contain the active ingredient Hydrocortisone, which is a glucocorticoid. Glucocorticoids are Adrenocorticosteroids, both synthetic and naturally occurring those are readily absorbed from the gastrointestinal tract. The medicine is used to treat people who lack adequate naturally generated cortisol. It is an effective way to treat illness involving inflammation in the body. The drug is on the WHO list of essential medicines required in a basic health system.

What is Hisone 5 mg used for?

The medicine Hisone is used as a replacement therapy in Addison’s disease (a disease characterized by progressive anemia, great weakness, bronze discoloration of the skin, and low blood pressure) or chronic adrenocortical insufficiency secondary to hypopituitarism (diminished hormone secretion by the pituitary gland).
It is also used in the inhibition of the secondary increase in adrenocorticotropic hormone secretion when aminoglutethimide is given for prostate and breast cancer.

Precautions

What medications interact with Hisone 5 mg?

Always inform your physician about the medicines you are taking till date. Give a complete list of prescription or non-prescription medicines and your other disease conditions if any. This way, your physician can decide and provide you with a list of medicines and other things that may interact with Hisone 5 mg tablets. The drugs that are mentioned below may interact with Hydrocortisone and can increase its sedation effect:

Anticonvulsants
Antifungal drugs
Antidepressants
Narcotics
Aspirin
Mifepristone
Cyclosporine
Azathioprine
Antiplatelet drugs like warfarin and clopidogrel

When should Hisone 5 mg not be used?

Hisone 5 mg tablets should not be used in patients with hypersensitivity to any ingredients of the medicine
Do not take it in case of systematic infections, unless specific anti-effective treatment is given
It should not be administered in patients with live virus immunization

Dosage Instructions

When should Hisone 5 mg be taken?

The amount of the medicine you consume each day will depend on your health condition. The number of tablets to be taken will be on the label of your medicine. If you are not sure about the dose you should take, you must talk to your physician. The usual dosage regimen is given below:

As a replacement therapy, the normal requirement is 10 mg to 30 mg daily (20 mg in the morning and 10 mg at night to mimic the circadian rhythm of the body).
As a combination treatment with aminoglutethimide, the usual recommended dose is 40 mg once daily, given as 10 mg with breakfast, 10 mg with dinner, and 20 mg at bedtime.

Do not stop taking Hisone tablets as it is dangerous to reduce your dose too quickly. Stopping the intake of this medicine may leave you without enough steroid hormones in your body. Also, this may cause withdrawal symptoms such as fever, general discomfort, and pain in muscles or joints, etc. Your physician will give you advice on how to reduce the intake of tablets if you need to do this.

How long should you take Hisone 5 mg?

Continue taking Hisone 5 mg tablets for as long as your physician tells you.

Missed dose of Hisone 5 mg

If you miss a dose, skip the missed dose of the drug.
Take the next as at the correct scheduled time.
Avoid taking two doses at once.

How should Hisone 5 mg be stored?

Keep Hisone tablets out of the sight and reach of children.
Store it at room temperature. Keep the tablets in its original packet to protect from light.

Side Effects

What are the side effects of Hisone 5 mg?

Every drug shows some side effects, the same way this medicine also has some side effects. The common ones are as follows:

Vomiting
Nausea
Dizziness
Restlessness
Acne
Heart burn
Increased sweating
Changes in menstrual period

Some rare side effects that need serious consideration are listed below:

Sore throat
Coughing
Difficulty in breathing
Swollen lips, face, tongue, and throat
Severe allergic reaction like rash and itching

How to Use

Infographics

FAQ

What is Hisone 5mg used for?

Hisone 5mg contains hydrocortisone, a steroid medicine that acts like a natural hormone made by your adrenal glands. It is used to treat conditions where the adrenal glands do not produce enough of this hormone — such as Addison's disease (adrenal insufficiency) and congenital adrenal hyperplasia. It is also used to reduce inflammation and suppress the immune system in conditions like severe allergies, asthma, arthritis, skin conditions, and inflammatory bowel disease.

How does hydrocortisone work as a steroid?

Hydrocortisone is a corticosteroid — it works in two main ways. First, it acts as a hormone replacement for people whose adrenal glands cannot produce enough cortisol (the body's natural stress hormone). Second, it reduces inflammation and dampens the immune system's overactivity in conditions like allergies, asthma, and autoimmune diseases. It works by switching off the signals inside cells that normally trigger inflammation and immune reactions.

What is the correct dose of Hisone 5mg?

The correct dose of hydrocortisone is very individual — it depends on the condition being treated and how your body responds. For adrenal insufficiency, doses are typically spread across 2–3 times a day to mimic the body's natural pattern of cortisol production (highest in the morning). Your doctor will set your exact dose carefully and will adjust it over time. Never change your hydrocortisone dose on your own, as the correct amount is crucial for your health.

When should hydrocortisone tablets be taken each day?

Hydrocortisone tablets are best taken with food or a glass of milk to protect the stomach. For adrenal insufficiency, doses are usually taken in the morning (the largest dose, to mimic the body's natural morning cortisol peak) and sometimes again around lunchtime or early afternoon — but not late in the day, as it can affect sleep. Your doctor will give you a specific schedule tailored to your needs. Stick to the same times each day for the best results.

Is Hisone 5mg used for Addison's disease?

Yes, hydrocortisone is the main treatment for Addison's disease (also called adrenal insufficiency). In this condition, the adrenal glands cannot produce enough cortisol on their own. Hydrocortisone tablets replace this missing hormone, helping your body maintain normal energy levels, blood pressure, and response to stress. People with Addison's disease usually need to take hydrocortisone every day for life, and will need higher doses during illness, injury, or surgery.

What should I do if I miss a dose of hydrocortisone?

If you forget a dose, take it as soon as you remember — unless it is almost time for your next dose. In that case, skip the missed dose and continue with your usual schedule. Never take a double dose to make up for a missed one. For people with Addison's disease, missing doses is more serious than for other conditions — if you vomit and cannot keep the tablet down, you may need an emergency injection. Always carry an emergency hydrocortisone kit if your doctor has prescribed one.

How does Hisone 5mg compare to Hisone 20mg?

Hisone 5mg and Hisone 20mg both contain hydrocortisone but at different strengths. The 5mg tablets are useful for fine-tuning doses — for example, taking 15mg would require three 5mg tablets rather than a single large one. The 20mg tablets are convenient for people on higher daily doses. Your doctor will tell you exactly which strength and how many tablets to take. The smaller tablet gives more flexibility in adjusting your daily dose precisely.

Do I need to increase my hydrocortisone dose when I am sick?

Yes — this is very important. When you are ill (even with something like a cold or flu), injured, or having surgery, your body needs more cortisol than usual. People taking hydrocortisone for adrenal insufficiency are advised to double or triple their dose during illness, high fever, or physical stress — this is called 'sick day rules'. Your doctor will teach you exactly when and how to do this. Failing to increase the dose during illness can lead to a dangerous situation called an adrenal crisis.

What are the side effects of hydrocortisone tablets?

When taken at low replacement doses (for adrenal insufficiency), hydrocortisone side effects are minimal. At higher doses used for inflammation, common side effects of hydrocortisone include weight gain, fluid retention (puffy face and ankles), increased appetite, mood changes, trouble sleeping, and raised blood sugar. Long-term use at high doses can weaken bones and lower immunity. Your doctor will aim to use the lowest effective dose to minimise these effects.

Can I stop taking hydrocortisone suddenly?

No — you should never stop taking hydrocortisone tablets suddenly, especially if you have been taking them for more than a few weeks. Your body may have reduced its own production of cortisol, and stopping abruptly can cause a dangerous withdrawal reaction, including extreme tiredness, weakness, dizziness, and in severe cases, a life-threatening adrenal crisis. Your doctor will gradually reduce your dose over time if you need to stop. Always follow their instructions carefully.

Can I buy Hisone (hydrocortisone tablets) online from PremiumRxDrugs?

Yes, Hisone 5mg and 20mg (hydrocortisone tablets) are available at PremiumRxDrugs.com. PremiumRxDrugs is a licensed pharmacy with over 10 years of experience providing genuine, manufacturer-sourced medicines to customers worldwide. We understand that hormone replacement medicines need to be reliable and authentic — and that is exactly what we deliver. Enjoy worldwide shipping, discreet packaging, and free shipping on qualifying orders.

Can hydrocortisone tablets affect blood sugar levels?

Yes, hydrocortisone — like all corticosteroid medicines — can raise blood sugar levels. This is because cortisol is a hormone that naturally causes the liver to release more glucose into the blood. In people with diabetes, hydrocortisone may make blood sugar harder to control and may require adjustments to diabetes medication. Even in people without diabetes, high doses over a long period can sometimes trigger 'steroid-induced diabetes'. Regular blood sugar monitoring is important for anyone on long-term steroid treatment.

Hisone 5mg