Nolvadex D 20mg
Available Dosages
| Description | Nolvadex D 20 mg is used to treat both early and advanced estrogen receptor positive breast cancer in the post and pre-menopausal women. |
|---|---|
| SKU | 1993 |
| Generic For | Nolvadex |
| Strength | 20mg |
| Manufacturer | Astra Zeneca, UK |
| Active Ingredient | Tamoxifen Citrate |
Out Of Stock
Nolvadex D 20mg (Tamoxifen Citrate) for Breast Cancer
Nolvadex D 20 mg (Tamoxifen)
Nolvadex D 20 mg tablets contain the active ingredient Tamoxifen citrate, an antineoplastic nonsteroidal selective estrogen receptor modulator that was discovered in 1967. It is a medicine that is used to prevent breast cancer in women and treat breast cancer in women and men. The drug is also being studied for other types of cancer. Tamoxifen is a type of hormone therapy (also called endocrine therapy).
Nolvadex general information
What is Nolvadex D 20 mg used for?
Nolvadex D 20 mg is used to treat both early and advanced estrogen receptor positive breast cancer in the post and pre-menopausal women. Moreover, it is the most common hormone treatment of male breast cancer. The drug is also approved by the Food and Drug Administration for the prevention of breast cancer in women who are at high risk of developing the disease. It is used in the treatment of patients who have had ductal carcinoma in situ and who have been treated with radiation and surgery.
Nolvadex D is also used:
- To treat mastalgia, desmoid tumors, endometrial cancer, and gynecomastia
- For induction of ovulation
- To treat Precocious puberty in women, secondary to McCune-Albright syndrome
- To reduce the risk in women who has Paget’s disease of the breast
How does Nolvadex D 20 mg work?
Nolvadex D 20 mg contains the active ingredient Tamoxifen, which belongs to a class of medicines, known as anti-oestrogens. The drug works by blocking the activity of estrogen in the breast. In this way, it stops the growth of some breast tumors that needs estrogen to grow.
What are the different doses of Nolvadex D?
Nolvadex D tablets are available to buy online from premiumrxdrugs.com in 20 mg strength. Buy Nolvadex D 20 mg online to grab various exciting offers.
What does Nolvadex 20 mg contain?
The active ingredient is Tamoxifen Citrate. Each Nolvadex D tablet contains 20 mg Tamoxifen.
What are the side effects of Nolvadex D 20 mg?
Like all drugs, Nolvadex D 20 mg tablets can cause side effects, although not everyone gets them. Check with your doctor if any of these common adverse effects persist or become bothersome:
- Pain or reddening around the site of the tumor
- Depression
- Increased bone or tumor pain
- Excessive tiredness
- Weight loss
- Headache
- Thinning of hair
- Nausea
- Loss of sexual ability in men
- Hot flashes
Immediately visit your doctor, if any of these severe adverse effects occur:
- Unusual bruising or bleeding
- Loss of appetite
- Swelling of the eyes, face, lips, tongue
- Fever
- Rash
- Blisters
- Muscle weakness
This is not a complete list of all adverse effects that may occur. If you have any questions about adverse effects, contact your doctor.
What medications interact with Nolvadex D 20 mg?
Nolvadex D interacts with many drugs and produces some serious health effects. Here are the common drugs that may interact with Nolvadex:
- Ropinirole
- Methimazole
- Pioglitazone
- Clozapine
- Cyclophosphamide
- Letrozole
- Cimetidine
- Anti-malaria drugs
- Ticlopidine
- Bromocriptine
- Rifampin
This medication guide does not contain all possible drug interactions. Therefore, before using this drug, tell your doctor about all medicines you use. Keep a list of all medications with you and share with your doctor.
When should Nolvadex D 20 mg not be used?
Nolvadex D 20 mg should not be used if:
- You are allergic to the active ingredient or any of the inactive ingredients of this medicine
- You are pregnant or plan to become pregnant
- You are breastfeeding. However, it is not known if Nolvadex D passes into mother’s milk
How should Nolvadex be taken?
- Nolvadex D is available in the form of a tablet. You can take it with or without food. Swallow the tablet with a glass full of water.
- To treat breast cancer in Adults: The recommended dose is 20 mg to 40 mg. Greater than 20 mg should be given in divided doses.
- To treat women with ductal carcinoma in situ (DSIC) following breast surgery and radiation: 20 mg daily for five years is the preferred dose.
- To reduce the risk of developing breast cancer in women at high risk of breast cancer: The recommended dose is 20 mg every day for five years.
- To treat breast cancer in adults-palliative: The recommended dose is 10 to 20 mg two times daily.
- Do not skip doses or stop using Nolvadex D tablets suddenly. Stopping the medicine suddenly may make your condition worse.
- You should only take the number of tablets that you have been told. Visit your nearest medical center immediately, if you think that you have taken too many Nolvadex D tablets by mistake.
- The dosage regimen may differ from the information contained in this document. In the case of any confusion, please consult your doctor.
How long should you take Nolvadex D 20 mg?
Continue taking Nolvadex D 20 mg tablets for as long as your doctor recommends.
Missed dose of Nolvadex D 20 mg
Take the missed dose as soon as you remember. Leave the missed dose if it is almost time for your next dose. Do not take an extra dose to make up the missed one. Try to take the drug at the same time each day as this will reduce the chance of missing the dose.
How should Nolvadex D 20 mg be stored?
- It should be stored at room temperature.
- Keep it out of the reach of children and away from pets. Avoid exposure to light, moisture, and heat.
- Do not place it in the bathroom or near a sink.
- Do not take any medicine after the expiry date, which is mentioned on the carton.
What is Tamoxifen Citrate and what condition does it treat?
Tamoxifen Citrate is a selective estrogen receptor modulator (SERM) primarily prescribed to treat and prevent certain types of breast cancer. Available as Nolvadex D 20mg, this hormone therapy medication blocks estrogen receptors in breast tissue, making it effective for estrogen-receptor-positive breast cancers. Doctors prescribe this anti-estrogen drug for early-stage and advanced breast cancer treatment, as well as risk reduction in high-risk patients. The active ingredient works by interfering with estrogen's ability to stimulate cancer cell growth, offering both therapeutic and preventive benefits for hormone-sensitive breast malignancies.
How does Tamoxifen Citrate work in the body?
Tamoxifen Citrate works by selectively blocking estrogen receptors in breast tissue while acting like estrogen in other parts of the body. When you take Nolvadex D 20mg, the active ingredient competes with natural estrogen for binding sites on cancer cells. By occupying these receptors, this SERM medication prevents estrogen from attaching and triggering cell division. This hormone-blocking action essentially starves estrogen-dependent tumours of the signals they need to grow and multiply. The selective nature of this breast cancer medicine means it provides anti-estrogen effects where needed while maintaining beneficial estrogen-like activity in bones and the cardiovascular system.
How long does Nolvadex D 20mg take to work?
Nolvadex D 20mg reaches peak blood levels within four to seven hours after taking a dose, though therapeutic effects develop gradually over weeks to months. While Tamoxifen Citrate begins blocking estrogen receptors immediately, measurable improvements in tumour markers or cancer progression typically require eight to twelve weeks of consistent use. This SERM medication builds up in your system over time, with steady-state concentrations achieved after approximately four weeks of daily dosing. Response timelines vary based on cancer stage, individual metabolism, and treatment goals. Most patients continue this hormone therapy for five to ten years as part of their comprehensive breast cancer treatment protocol.
When and how should I take Nolvadex D 20mg?
Take Nolvadex D 20mg once or twice daily as prescribed by your oncologist, with or without food. Most patients find morning dosing convenient for this hormone therapy, though you can take Tamoxifen Citrate at any consistent time that suits your routine. Swallow the tablet whole with water—don't crush or chew it. If your doctor prescribes a twice-daily regimen, space doses approximately twelve hours apart. Consistency matters more than timing; taking this breast cancer medication at the same time daily maintains stable drug levels. Always follow your prescription exactly and inform your healthcare provider about all medications you're taking to avoid interactions.
Is Nolvadex D 20mg safe for long-term use?
Nolvadex D 20mg is considered safe for extended use, with most breast cancer patients taking Tamoxifen Citrate for five to ten years under medical supervision. Long-term studies of this SERM medication show sustained benefits that outweigh risks for appropriate candidates. Your oncologist will monitor you regularly through blood tests, eye examinations, and gynaecological assessments to catch any potential complications early. While this hormone therapy carries some risks with prolonged use—including endometrial changes and blood clot formation—these remain relatively uncommon. The protective benefits against breast cancer recurrence typically justify continued treatment for the full recommended duration in eligible patients.
Can I take Nolvadex D 20mg with other medicines?
Nolvadex D 20mg can interact with various medications, so disclosure of all drugs and supplements is essential. Tamoxifen Citrate metabolism involves liver enzymes that certain antidepressants, particularly SSRIs like fluoxetine and paroxetine, may inhibit, potentially reducing effectiveness. Blood thinners like warfarin combined with this SERM medication increase bleeding risk and require careful monitoring. Some chemotherapy agents, hormone therapies, and even herbal supplements can alter how your body processes this breast cancer treatment. Rifampicin and certain antifungals also affect Tamoxifen levels. Your pharmacist at PremiumRxDrugs can screen for interactions when you order, providing an additional safety check.
How does Nolvadex D 20mg compare to similar medicines in its class?
Nolvadex D 20mg remains the gold-standard SERM for premenopausal breast cancer patients, though several alternatives exist within hormone therapy. Compared to aromatase inhibitors like letrozole or anastrozole, Tamoxifen Citrate works differently—blocking estrogen receptors rather than reducing estrogen production. Aromatase inhibitors suit postmenopausal women better, while this selective estrogen receptor modulator benefits premenopausal patients and those with contraindications to aromatase-blocking drugs. Raloxifene, another SERM medication, offers similar receptor-blocking action but is approved primarily for prevention rather than active treatment. Nolvadex typically causes fewer joint problems than aromatase inhibitors, making it preferable for patients prone to arthralgia.
Is the generic Tamoxifen Citrate as effective as branded versions?
Generic Tamoxifen Citrate contains the identical active ingredient as branded Nolvadex D 20mg and delivers equivalent therapeutic effects for breast cancer treatment. Regulatory authorities in the USA, UK, Australia, and Canada require generic hormone therapies to demonstrate bioequivalence—meaning they work in your body exactly as the brand-name SERM medication does. Both versions block estrogen receptors with the same efficacy, following strict pharmaceutical manufacturing standards. The primary difference lies in price rather than performance, with generic options offering substantial savings. Whether you choose branded Nolvadex or generic Tamoxifen from PremiumRxDrugs, you receive the same cancer-fighting selective estrogen receptor modulator your oncologist prescribed.
Why do patients choose PremiumRxDrugs for Nolvadex D 20mg?
Patients choose PremiumRxDrugs for Nolvadex D 20mg because of competitive pricing on both branded and generic Tamoxifen Citrate without compromising medication authenticity. This licensed pharmacy sources all hormone therapy medications directly from manufacturers, eliminating counterfeit risks that plague unregulated suppliers. The combination of discreet packaging, reliable worldwide shipping with free delivery options, and easy prescription management creates a seamless experience for long-term breast cancer treatment. Having served customers for over ten years across the USA, UK, Australia, and Canada, PremiumRxDrugs has built trust through consistent quality and service. Their straightforward reorder system particularly benefits patients on multi-year SERM medication protocols.
What are the common side effects of Tamoxifen Citrate?
Common side effects of Tamoxifen Citrate include hot flashes, night sweats, and vaginal discharge or dryness, affecting many patients taking this SERM medication. Some people experience nausea, fatigue, or mood changes while on this hormone therapy. Menstrual irregularities occur frequently in premenopausal women, sometimes leading to temporary or permanent changes in periods. Joint pain, headaches, and slight weight fluctuations are also reported with this breast cancer treatment. Most side effects remain mild to moderate and often diminish after the first few months. More serious but less common reactions include blood clots, stroke symptoms, or vision changes, which require immediate medical attention if they occur.
Who should avoid taking Tamoxifen Citrate?
Women who are pregnant, planning pregnancy, or breastfeeding should not take Tamoxifen Citrate, as this hormone therapy can harm developing babies. Patients with a history of blood clots, deep vein thrombosis, pulmonary embolism, or stroke face increased risks with this SERM medication and may need alternative breast cancer treatments. Those with known hypersensitivity to the active ingredient should avoid this selective estrogen receptor modulator entirely. Women requiring concurrent treatment with certain anticoagulants may face complications. Patients with severe liver impairment need careful evaluation before starting this medication. Your oncologist will review your complete medical history, including clotting disorders and cardiovascular conditions, to determine if this hormone therapy suits your situation.
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