Pentids 400mg
Available Dosages
| Description | |
|---|---|
| SKU | 478 |
| Generic For | Penicillin G |
| Strength | 400mg |
| Active Ingredient | Penicillin G Potassium |
Out Of Stock
Pentids 400mg (Penicillin G Potassium) – Affordable Penicillin G Alternative
Pentids 400mg is an oral prescription medicine prescribed for treating a variety of bacterial infections. It is effective in treating infections of the throat, nasal sinuses, respiratory tract, rheumatoid fever, skin and soft tissue, and sexually transmitted diseases like syphilis.
Pentids contains the active ingredient Penicillin G, an antibiotic used to treat many bacterial infections. It works by inhibiting the growth of bacteria that cause the infection. When taken as advised by the healthcare specialist, it usually makes you feel better quite quickly. You must continue taking the tablet as instructed, even when you feel better, to ensure that all bacteria are destroyed and do not become resistant. For treatment of syphilis (a serious bacterial infection that can affect multiple parts of the body), Pentids tablets kill the bacteria and prevent them from spreading and causing long-term complications. Early treatment with Penicillin G supports faster recovery and reduces the risk of serious health problems. When it comes to preventing rheumatic fever caused by the bacterium Streptococcus, antibiotic therapy helps relieve inflammation and prevent disease recurrence.
Tell the healthcare specialist before consuming Pentids 400mg if you are hypersensitive to the drug or its components. Also inform them about any liver diseases, kidney diseases, fever, or asthma, history of allergies (you have allergies to food, medicines, and other substances), taking contraceptives or being below the age of 16 years if you are a woman of childbearing potential. You should discuss the positives and negatives of taking Penicillin G during pregnancy. Breastfeeding women are advised not to take Penicillin G as it may pass into the breast milk and harm the nursing baby. Suppose your doctors have told you that you have an intolerance to some sugars. This medication may cause dizziness. Do not drive or use machinery while taking Penicillin G, as these activities may require a high degree of mental attention. Avoid consuming Pentids if you are taking any of the following medicines: Oxytetracycline, Probenecid, Tetracycline, Typhoid Vaccine Live, Minocycline, Methotrexate, Mycophenolate, Lymecycline, BCG Vaccine Live, Doxycycline, Demeclocycline.
Like other medicines, Pentids 400mg may cause adverse effects. Seek medical attention if you develop nausea, pain in the stomach, headache, white patches inside your mouth, vomiting, etc.
The adverse reactions of Pentids can also be dangerous. Visit the doctor immediately in the following situations.
- Decreased urination
- Severe skin rashes
- Confusion
- Weakness
- Watery diarrhoea
- Agitation
- Easy bruising/bleeding
- Behavioural changes
If any of these side effects persist or worsen, seek immediate medical help. Seeking medical help may enable your provider to provide supportive treatments or adjust your dosage.
How to use it? (infographics and instructions)
The drug is available as tablets. You may take the drug one hour before or two hours before meals. Swallow the medicine with plenty of water. Take the tablet exactly as prescribed by the doctor. Do not alter the dosage plan. In general, the dose regimen varies from patient to patient and depends on the patient's age, weight, and condition. The paediatric dose of Penicillin G depends primarily on the patient's weight. The doctor may prescribe the medication based on the pediatric patient's body weight. Take the medicine regularly to get the best results. To help you remember, take the tablets at the same time each day.
In some cases, the condition may worsen when the medicine is stopped suddenly. Your dose may need to be slowly decreased immediately, in the case of an overdose of Pentids. You may experience:
- Appearance of rashes on the skin
- Change in the behaviour
- Confusion
- Decreased urination
Take the tablets for as long as your healthcare provider recommends.
Missed Dose - If you have forgotten a dose, take it as soon as you remember and resume your usual dosing schedule. If the next dose is due soon, leave the forgotten dose and take the next one. Do not double the dose to make up for the forgotten dose.
Precautions
Tell the healthcare specialist before consuming Pentids if you are hypersensitive to the drug or its components. Also inform them about any liver diseases, kidney diseases, fever, or asthma, history of allergies (you have allergies to food, medicines, and other substances), taking contraceptives or being below the age of 16 years if you are a woman of childbearing potential. You should discuss the positives and negatives of taking Penicillin G during pregnancy. Breastfeeding women are advised not to take Penicillin G as it may pass into the breast milk and harm the nursing baby. Suppose your doctors have told you that you have an intolerance to some sugars. This medication may cause dizziness. Do not drive or use machinery while taking Penicillin G, as these activities may require a high degree of mental attention. Avoid consuming Pentids if you are taking any of the following medicines: Oxytetracycline, Probenecid, Tetracycline, Typhoid Vaccine Live, Minocycline, Methotrexate, Mycophenolate, Lymecycline, BCG Vaccine Live, Doxycycline, Demeclocycline.
What is Pentids 400mg used for?
Pentids 400mg contains penicillin G (benzylpenicillin potassium) at double the standard tablet strength. This higher dose is used for treating streptococcal infections that require a stronger antibiotic effect — such as moderate-to-severe strep throat infections — and for long-term preventive therapy against rheumatic fever in adults and older children who need a higher daily dose. It is particularly useful when the infection needs a more robust response or when a lower dose has not provided adequate protection.
Who should not take Pentids 400mg?
Pentids 400mg is contraindicated in anyone with a known penicillin allergy or a documented allergy to any beta-lactam antibiotic. People with severe kidney impairment should use it with caution and may require a dose adjustment, as penicillin G is cleared from the body through the kidneys. If you have a history of anaphylaxis (a severe, whole-body allergic reaction) to any medication, always inform your prescriber before starting any antibiotic. Do not use leftover antibiotics or take someone else's prescription.
What is the standard dose of Pentids 400mg?
For acute streptococcal infections, the typical adult dose is one tablet (400mg) taken two to three times a day for 10 days. For ongoing preventive therapy against rheumatic fever, the dosing schedule is determined by the doctor based on the individual's age, cardiac involvement, and risk level. Always follow the dosing instructions given by your doctor precisely — taking the full course (for acute treatment) or never missing doses (for preventive use) is essential for the medicine to work as intended.
Should Pentids 400mg be taken with or without food?
Penicillin G is best absorbed on an empty stomach — take Pentids 400mg at least 30 minutes before eating or 1–2 hours after a meal for maximum absorption into the bloodstream. If the tablet causes stomach irritation when taken on an empty stomach, a small, light snack can reduce discomfort, but try to avoid heavy meals close to the time of each dose. Take the tablet with a full glass of water and try to take it at the same time(s) each day to maintain consistent levels in your body.
Can children take Pentids 400mg?
Yes — Pentids 400mg can be used in older children and teenagers, particularly those requiring higher doses for rheumatic fever prevention or treatment of streptococcal infections. The dose for children is based on body weight, and the doctor will confirm whether the 400mg strength is appropriate. Younger children may use the 200mg strength or a liquid formulation. For long-term preventive treatment, the dose and schedule are specifically tailored by the doctor to the child's weight, age, and medical history.
Is Pentids 400mg safe during pregnancy?
Penicillin G is one of the better-studied antibiotics in pregnancy and is considered relatively safe when prescribed by a doctor. It is used in pregnancy for treating certain bacterial infections, including strep-related ones. Small amounts pass into breast milk, but at usual doses this is not considered harmful to a nursing infant. If you are pregnant or breastfeeding and require antibiotic treatment, your doctor will assess whether penicillin G is the most appropriate choice for your situation.
How does Pentids 400mg differ from Pentids 200mg?
Both Pentids 200mg and 400mg contain the same antibiotic — penicillin G (benzylpenicillin potassium) — but at different strengths. The 400mg tablet contains twice the dose per tablet. Your doctor will prescribe the appropriate strength based on your weight, the severity of the infection, and your specific treatment plan. For acute infections requiring a stronger dose or for larger adults needing higher prophylactic (preventive) doses, the 400mg tablet is more convenient as fewer tablets may be needed per day.
Can I drink alcohol while taking Pentids 400mg?
Alcohol does not directly interact with penicillin G in a dangerous way. However, during treatment for an active infection, alcohol is best avoided as it can slow healing and impair immune function. For those on long-term preventive therapy, moderate alcohol consumption is less likely to affect the medication, but it is always wise to discuss this with your doctor. Stay well hydrated with water, especially if you have a fever or are sweating, as dehydration can affect how the antibiotic is processed in the body.
Does Pentids 400mg interact with other medications?
Penicillin G can interact with a small number of other medicines. It may increase the level of methotrexate in the blood, raising the risk of methotrexate side effects. Probenecid (used for gout) slows the removal of penicillin G from the kidneys, which can increase its levels in the body — sometimes used intentionally under medical supervision. Penicillin G may also slightly reduce the effectiveness of combined oral contraceptive pills. Always inform your doctor and pharmacist of all medicines you are taking before starting this antibiotic.
Why is penicillin G still used when newer antibiotics are available?
Despite being one of the oldest antibiotics, penicillin G remains effective and is specifically recommended for Group A Streptococcus infections — including the treatment and prevention of rheumatic fever — because Streptococcus has, remarkably, not developed significant resistance to penicillin after decades of use. For these specific indications, it remains the recommended first-line treatment in international guidelines. Its long safety record, low cost, and proven effectiveness mean it continues to play an important role in infectious disease medicine.
What are the common side effects of penicillin G (benzylpenicillin)?
Common side effects of penicillin G tablets include nausea, stomach discomfort, diarrhoea, and an unpleasant taste in the mouth. Taking the tablet with a small amount of water on an empty stomach (rather than a full meal) as recommended can help minimise digestive upset. Some people develop oral or vaginal thrush (caused by yeast overgrowth when the natural bacterial balance is disrupted by the antibiotic) during prolonged courses. Skin rashes are reported in some individuals and should be reported to your doctor.
What side effects of penicillin G require urgent medical attention?
Seek emergency care immediately for any signs of a severe allergic reaction: widespread hives or itchy rash, swelling of the face, lips, tongue, or throat, difficulty breathing, dizziness, or rapid heartbeat. Anaphylaxis (a life-threatening allergic reaction) is the most serious risk with penicillin antibiotics. Severe diarrhoea — especially if watery, bloody, or accompanied by severe cramps — during or after the antibiotic course may indicate a C. difficile gut infection and needs prompt medical assessment. Report any unexpected or worsening symptoms to your doctor without delay.
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