Zocon DT 100 mg
| SKU | 428 |
|---|---|
| Generic For | Diflucan |
| Strength | 100 mg |
| Manufacturer | FDC |
| Active Ingredient | Fluconazole |
| Pack Size | Qty | Price Per Pill or Unit | Price | Cart | |
|---|---|---|---|---|---|
| 32 Tablet/s | US$ 0.94 | US$ 30.0029%US$ 42.00 | |||
|
|||||
| 64 Tablet/s | US$ 0.94 | US$ 60.0029%US$ 84.00 | |||
|
|||||
| 128 Tablet/s | US$ 0.78 | US$ 100.0031%US$ 145.00 | |||
|
|||||
Zocon DT 100mg – Affordable Diflucan Alternative for Fungal & Yeast Infections
Zocon DT 100 mg is a clinically approved antifungal medication that is formulated to treat various types of fungal infections. It is effective in preventing fungal infections in people who are undergoing bone marrow transplantation. The active component of the medicine is Fluconazole, which falls into the category of medications known as triazole antifungal. The medicinal ingredient is primarily fungistatic, however, it may exert fungicidal action against certain organisms specifically Cryptococcus. The safety and efficacy of the drug have been established in treating infections caused by candida and various other types of fungi.
What is Zocon DT used for?
Zocon DT is indicated for:
- Skin infections
- Vaginal infections
- Urinary tract infections
- Cryptococcal meningitis
- Pneumonia
The pharmaceutical product is specifically for the prevention of infections in patients whose immune system is very weak.
Your physician may prescribe this anti-fungal agent for other conditions that have not been listed here.
How does Zocon DT work?
The ingredient present in the antifungal medication prevents the growth of the fungi and yeast that are responsible for causing infection.
What medications interact with Zocon DT?
Following is a list of drugs that can interact with your anti-fungal drug:
- Warfarin
- Rifabutin
- Isoniazid
- Rifampin
- Tacrolimus
- Zidovudine
- Theophylline
- Buspirone
- Benzodiazepines
- Rifabutin
- Nisoldipine
- Losartan
- Tricyclic antidepressants
- Tolbutamide
- Alfentanil
- Tofacitinib
- Amphotericin b
- Voriconazole
When should Zocon DT not be used?
Do not take this 100 mg tablet if you are allergic to the active or inactive ingredients present in the formulation.
Exercise caution in the situations given below:
- Renal impairment
- Underlying liver disorder
- Geriatrics
- Pregnancy to avoid congenital effects
- Lactation
How long should Zocon DT be used?
Use Fluconazole 100 mg as long as it is recommended to you. Do not stop in between during the treatment. If the condition still does not improve after this time, talk to your physician.
Missed dose of Zocon DT
Remember to take the dose of your anti-fungal medication on time. If you miss a dose, take it as soon as you remember with a full glass of water. If it is time for the next dose (scheduled dose), then avoid taking it and take the next dose on time.
How should Zocon DT be stored?
- Keep it out of the reach of children and away from pets
- Do not freeze it. Store at room temperature
What are the side effects of Zocon DT?
The possible side effects associated with Zocon DT are:
- Dizziness
- Seizures
- Headache
- Hypertriglyceridemia
- Hypokalemia
- Stevens-johnson syndrome
- Abdominal discomfort
- Nausea
- Hepatotoxicity
- Diarrhea
- Vomiting
- Allergic reactions including anaphylaxis
How should Zocon DT be used?
To treat your fungal infections, you must take this antifungal medication once a day with or without food.
Esophageal candidiasis
To treat adults, 200 mg is the suggested dose. Your physician may increase your dose to 100 mg once daily for at least 14 days. The maximum recommended dose is 400 mg and must administer depending on the health condition.
To treat Children above 14 days, the initial suggested dose is 6 mg, then your physician may increase it 3 to 12 mg/kg a day for at least 21 days.
Oropharyngeal candidiasis
For the treatment of adults, 200 mg is the preferred dose; your physician may increase your dose up to 100 mg a day for at least 14 days.
To treat children above 14 days, the initial suggested dose is 6 mg/kg, and then it may increase to 3mg/kg/day for 21 days. To know about the dose regimen for neonates, please discuss with your physician.
Cryptococcal meningitis
For patients suffering from cryptococcal meningitis, 400 mg once daily is the preferred dose. The dose may increase to 200 to 800 mg once a day for at least 10 to 12 week.
200 mg once daily should be taken for suppressive therapy.
For the treatment of children- The initial suggested dose is 12 mg/kg a day. Your dose may be increased by up to 6 to 12 mg/kg daily for at least 10 to 12 weeks. 6 mg/kg daily is the suggested dose for suppressive therapy.
Systemic Candidiasis
Your physician may recommend 400 mg as an initial dose these patients. Your dose may increase to 200 to 800 mg daily a day for about one month.
To treat children with systematic candidiasis, 6 to 12 mg/kg daily is the dose that needs to take for 28 days.
Vaginal candidiasis
For females suffering from vaginal candidiasis, the usual dose is 150 mg daily for three days then weekly for six months.
To prevent Candidiasis after bone marrow transplant
The treatment for adults may start with the dose of 400 mg once that a patient needs to take daily and continue for seven days.
Children patients must take 10 to 12 mg/kg daily. The maximum recommended dose is 600 mg daily.
When should Zocon DT not be used?
The antifungal agent is not suitable for patients who have ever developed an allergic reaction to any of the ingredients of the medication. The symptoms may include trouble breathing, itching, reddening of the skin, etc.
What is Zocon DT 100mg used for?
Zocon DT 100mg contains fluconazole 100mg in a dispersible tablet (DT) formulation. Fluconazole is a triazole antifungal used for: oropharyngeal and oesophageal candidiasis (thrush), vaginal candidiasis, cryptococcal meningitis (maintenance therapy), mucocutaneous candidiasis, tinea infections (ringworm, tinea versicolor), and systemic fungal infections in immunocompromised patients. The 100mg dose treats oropharyngeal candidiasis (200mg loading + 100mg daily for 14 days), oesophageal candidiasis, and non-genital mucosal candida infections. The dispersible formulation is convenient for patients with swallowing difficulty.
How does fluconazole in Zocon DT 100mg work against fungal infections?
Fluconazole inhibits the cytochrome P450 enzyme lanosterol 14-alpha-demethylase — the key fungal enzyme in ergosterol biosynthesis. Ergosterol is the equivalent of cholesterol in fungal cell membranes — it maintains membrane integrity and function. Without ergosterol, the fungal cell membrane becomes permeable and dysfunctional, inhibiting fungal growth (fungistatic) and ultimately causing cell death (fungicidal at higher concentrations). Fluconazole has excellent oral bioavailability (>90%), penetrates tissues including the CNS exceptionally well, and has a long half-life (30 hours) enabling once-daily dosing.
How should Zocon DT 100mg be dissolved and taken?
Zocon DT 100mg is a dispersible tablet — dissolve in approximately 5–10ml of water, stir, and drink immediately. It can also be swallowed whole. Take with or without food (bioavailability is not significantly affected by food). The dispersible formulation is designed for patients who have difficulty swallowing tablets. For oral candidiasis: 200mg loading dose on day 1 (two 100mg DTs), then 100mg once daily for 13 more days (14 days total). Maintain consistent daily dosing. Complete the full course even if symptoms resolve earlier — incomplete treatment allows fungal recurrence.
What drug interactions affect Zocon DT 100mg?
Fluconazole is a potent CYP2C9 and CYP3A4 inhibitor — interactions are clinically significant even at 100mg. Major interactions: warfarin (INR increases dramatically — reduce warfarin by 30–50% and monitor INR daily); phenytoin (levels increase significantly); sulfonylureas (glibenclamide, glipizide — hypoglycaemia risk); ciclosporin and tacrolimus (levels increase — renal toxicity risk); statins (simvastatin/lovastatin levels increase markedly — rhabdomyolysis risk; switch to fluvastatin or rosuvastatin); QT-prolonging drugs (additive risk); rifampicin (reduces fluconazole levels by 25%). Always review co-medications before prescribing fluconazole.
Is Zocon DT 100mg safe in patients with renal impairment?
Fluconazole is primarily renally excreted as unchanged drug. Dose adjustment is required: eGFR >50: standard dose 100mg once daily; eGFR 11–50: 50% dose reduction (50mg once daily, or 100mg every 48 hours); haemodialysis patients: full 100mg dose after each dialysis session. Fluconazole is not significantly nephrotoxic itself — dose adjustment prevents drug accumulation causing hepatotoxicity and QT prolongation. Monitor renal function in patients with impairment. Hepatotoxicity is the key safety concern — monitor LFTs monthly in patients on extended courses.
How does Zocon DT 100mg compare to itraconazole for oral candidiasis?
Fluconazole 100mg daily and itraconazole 200mg daily are both triazole antifungals effective for oropharyngeal candidiasis. Fluconazole advantages: superior bioavailability, simpler dosing, better CNS penetration, and more predictable pharmacokinetics. Itraconazole advantages: broader spectrum covering Aspergillus and some dermatophytes that fluconazole misses. For oropharyngeal candidiasis, fluconazole is the preferred first-line triazole — established efficacy, better tolerability, and more predictable drug levels. Fluconazole-resistant Candida (C. krusei inherently resistant; C. glabrata often resistant) require itraconazole, voriconazole, or echinocandin alternatives.
Is Zocon DT 100mg the same as Diflucan 100mg?
Yes. Zocon DT 100mg and branded Diflucan 100mg both contain fluconazole 100mg in bioequivalent formulations (Zocon DT is dispersible tablet vs. Diflucan's standard tablet but both deliver equivalent fluconazole exposure). Zocon DT is the generic alternative providing the same antifungal therapy at significantly lower cost.
Can I order Zocon DT 100mg from PremiumRxDrugs for international delivery?
Yes. PremiumRxDrugs.com ships Zocon DT 100mg to the USA, UK, Australia, and many other countries. Our genuine manufacturer-verified antifungal medications, competitive pricing, and free worldwide shipping on qualifying orders make us a reliable international source for fluconazole therapy.
What side effects does Zocon DT 100mg cause?
Common: nausea, abdominal discomfort, headache, and rash. Hepatotoxicity (rare at standard doses — elevated LFTs in ~2% of patients, symptomatic hepatitis much rarer; more common with prolonged high-dose therapy). QT prolongation (risk increases with drug interactions — ECG monitoring if combined with QT-prolonging drugs). Stevens-Johnson syndrome (very rare — stop immediately if severe skin reaction). Adrenal effects (theoretical at high doses — fluconazole inhibits cortisol synthesis mildly). Report any yellow skin/eyes, severe rash, or cardiac symptoms immediately. Side effects are generally mild at 100mg daily dosing.
What monitoring is required during extended Zocon DT 100mg therapy?
For standard 14-day courses: no special monitoring required in otherwise healthy patients. For extended or repeated courses: LFTs before and monthly during therapy — fluconazole hepatotoxicity is dose and duration-dependent; renal function — dose adjustment as above; ECG if combined with QT-prolonging drugs; drug interaction review at each prescription (fluconazole's CYP2C9/3A4 inhibition affects many common medications). In immunocompromised patients (HIV, transplant) on long-term fluconazole prophylaxis: resistance surveillance — Candida speciation and susceptibility testing if breakthrough infection occurs.
What is the correct storage for Zocon DT 100mg dispersible tablets?
Store Zocon DT 100mg tablets in a cool, dry place below 25°C away from direct sunlight and moisture. Keep the container tightly closed. Dispersible tablets are more sensitive to humidity than standard tablets — moisture can affect the disintegration properties. Do not store in the bathroom or near a kitchen sink. Keep out of reach of children. Check the expiry date before use. If a tablet appears discoloured, crumbled, or does not disperse properly in water, discard and use a fresh tablet. Opened blister packs should be used promptly. The dissolved suspension must be taken immediately after preparation — do not store prepared suspension.
Login
Sign Up
Login
Sign Up