A Ret .025% Gel

A Ret Gel 0.025% (Tretinoin .025 gel )    

A-Ret .025% gel contains Tretinoin, a carboxylic acid form of vitamin A, a first-generation topical retinoid. It is commonly used to treat acne and keratosis pilaris (a harmless skin condition that causes rough, dry patches and tiny bumps, usually on the cheeks, upper arms, buttocks, and thighs). Tretinoin is on the WHO list of essential medicines.

A-Ret .025 gel is indicated for topical use in treating acne vulgaris, blackheads, papules, and pustules predominate. It is not recommended as monotherapy for acne conglobata.

Tretinoin 0.025, a metabolite of retinol, is structurally and pharmacologically related to vitamin A, which regulates cell growth and regenerates the outer layer of the skin. It makes the surface layer of the skin thinner and pores less likely to become blocked, reducing the occurrence of blackheads, whiteheads, and pimples.

How to use?

• A Ret gel should be applied daily to the skin areas where lesions appear. Clean the area before you apply the gel, and pat dry with a soft cotton cloth. Use enough quantity to cover the entire affected area lightly. Don't forget to wash your hands properly after the application.
• Don't let this topical medication contact the delicate parts of your face like eyes, nose, or lips. Wash them thoroughly with water if they are exposed to the medication accidentally.
• After using the medicine, a temporary feeling of warmth or slight stinging may occur. Reducing the application frequency or discontinuing the treatment is necessary in this case. The frequency of application may be increased, or treatment may be resumed when the patient can tolerate the treatment. If you have any doubts, please ask your physician.
• The frequency and concentration of the drug should be closely monitored by careful observation of the therapeutic response and skin tolerance. During the initial days of the treatment, an apparent exacerbation of inflammatory lesions may occur. It may be caused due to the action of the drug or previously seen lesions, which should not be considered a reason to discontinue the treatment.
• Therapeutic results should be seen after two to three weeks, but more than six weeks of the treatment may be required before definite beneficial effects are noticed.
• Once an adequate result has been achieved, it may be possible to maintain the improvement with less frequent drug applications.
• Patients treated with A-Ret gel acne treatment may use cosmetics, but the affected area to be treated should be cleansed thoroughly before the medicine is applied.
• If the gel is applied excessively, no rapid or better results will be obtained, and marked redness, peeling of the skin, and discomfort may occur. Please consult your physician in case of an accidental overdose.
• Use A-Ret gel tretinoin 0.025 as long as it is recommended to you. Do not stop during the treatment. Call your physician if the acne still does not improve after this time.

Precaution and warning

Concomitant topical medication, abrasive soaps and cleansers, cosmetics that have a strong drying effect, and products with high concentrations of astringents, alcohol, spices, or lime should be used cautiously because of the possible drug interaction with ARet gel. Particular caution should be taken while using preparations containing keratolytic agents such as benzoyl peroxide, salicylic acid, or sulfur with Tretinoin.

A Ret gel 0.025% should not be used in patients with hypersensitivity to Tretinoin or any ingredients in this formulation. Do not use this formulation on sunburned, wind-burned, irritated, dry, peeled, or scaly skin or wounds. Apply it only after the area of the condition is completely healed. While using A Ret gel, your skin may become sensitive to sunlight and UV radiation. Therefore, you must avoid unnecessary exposure to sunlight and artificial UV rays (tanning beds or sunlamps). Wear good sunscreen and protective clothing if you venture out in the sun.

Side Effects

A-Ret gel is well tolerated after nightly application. Side effects have been limited to mild irritation, peeling, and erythema, especially in the early stage of treatment. Some patients may experience temporary warmth or slight stinging after application.

If immoderate reactions occur, the frequency of application may be reduced, or treatment discontinued temporarily till the reactions become less intense. The frequency or dose may then be adjusted to a level the patient can tolerate. Transitory hypopigmentation or hyperpigmentation has been reported with the repeated topical use of the drug. Some individuals have also been reported to have heightened susceptibility to sunlight during the treatment with tretinoin A-Ret gel.