Premarin Vaginal Cream Usage

by | Aug 17, 2021 | Women Health | 0 comments

Premarin vaginal cream is a solution for women who experience symptoms of atrophic vaginitis, including vaginal dryness, itching, irritation, itching, and painful sex. The cream is a vaginal estrogen that has been shown to relieve these symptoms and improve the quality of life of these women.

Possible uses of Premarin  vaginal cream

Premarin vaginal cream is commonly prescribed to postmenopausal women to improve the quality of the vagina in atrophic vaginitis that occurs most often after menopause. The vaginal condition also makes intercourse painful. Premarin cream is the perfect topical preparation for soothing the symptoms of atrophic vaginitis that includes burning sensation, irritation, itching and dryness in and around the vagina. It is the treatment of choice in women. If these genital symptoms are troubling you, it could be your reduced estrogen level in the tissues around the genital area. Such symptoms usually respond to estrogen-based topical cream like Premarin.

The working mechanism of Premarin vaginal cream

The topical formulation contains conjugated estrogens cream as the main ingredient. It supplies estrogen directly into the vaginal tissues and provides relief from the vaginal symptoms of menopause such as itching, irritation, and dryness. The topical formulation can be used every day for three weeks, followed by a week off.

Dosage & Directions for use

You should follow the dosage regimen prescribed by your physician. Estrogen preparation should be used at the lowest dose possible for the treatment of atrophic vaginitis symptoms only as long as needed. Be in touch with your physician so that he/she will be able to know whether you still need treatment or not. Do not share premarin cream uses with others, even if they have the same vaginal symptoms. It may not be suitable for them and may harm them. For applying the solution, firstly remove the cap, gently squeeze the tube to force sufficient prescribed dose to come out and use on the vaginal opening or the affected area around your vagina. Wash your hands before and after applying the solution.

Side effects

The side effects of Premarin vaginal cream may include:

  • Joint pain, leg pain
  • Breast pain
  • Leaking of milk from the nipple
  • Bleeding, spotting, changes in menstrual flow, painful periods
  • Hair loss
  • Inflammation of the vagina, vaginal itching, and discharge
  • Weight changes
  • Mood changes, irritability
  • Change in libido
  • Headaches
  • Dizziness
  • Nausea accompanied by vomiting
  • Abdominal pain, bloating
  • Itching, rash, hives, acne

If any of these unwanted effects occur and affect you severely, inform your physician.

Drug interactions

Tell your physician if you are taking any medication including prescription, non-prescription, supplements, or herbal products. Certain remedies such as St. John’s Wort, medications to treat high blood pressure, diabetes, sleep disorders, tuberculosis, seizures, anxiety, and pain may affect the way how to conjugate estrogen works. You should also inform your physician if you use latex or rubber diaphragms or cervical caps.


Completely avoid the topical preparation if you have a history of breast cancer or undiagnosed abnormal genital bleeding. Discontinue using this estrogen formulation if the loss of vision, cholestatic jaundice, or hypercalcemia occurs. This cream may increase the risk of blood clots in the large veins in postmenopausal women taking combined estrogen and progestin preparation.  

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